Epistasis and its possible effects on transmission disequilibrium tests

Annals of Human Genetics

Volumn 65, Issue 6, 2001, Pages 565-575

  Wilson, S R ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONTROLLED STUDY; COVARIANCE; DATA ANALYSIS; DISEASE PREDISPOSITION; ENVIRONMENTAL FACTOR; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ANALYSIS; GENETIC DISORDER; GENETIC EPISTASIS; GENETIC MODEL; HUMAN; HYPOTHESIS; MALE; METHODOLOGY; PENETRANCE; POPULATION GENETICS; PRIORITY JOURNAL; PROBABILITY; STATISTICAL ANALYSIS;

EID: 0035717139     PISSN: 00034800     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1469-1809.2001.6560565.x     Document Type: Article

References (12)

1. Bickeböller, H. & Clerget-Darpoux, F. (1995). Statistical properties of the allelic and genotypic transmission/disequilibrium test for fallelic markers. Genet. Epidemiol. 12, 865-870.
2. Bierut, L. J., Rice, J. P., Kdenberg, H. J., Goate, A., Foroud, T., Cloninger, G. R., Begleiter, H., Comically, P. M., Crowe, R. R., Hesselbrock, V., Li, T. K., Nurnberger, J. I. Jr, Porjesz, B., Schuckit, M. A. & Reich, T. (2000). Family-based study of the association of the dopamine D2 receptor gene (DRD2) with habitual smoking. Am. J. Med. Genet. 90, 299-302.
3. Dong, J. (1998). Simpson's paradox. In: Armitage, P. and Colton, T. Encyclopedia of Biostatistics, J. Wiley (Chichester), pp. 4108-4110.
4. Ewens, W. J. (1999). Statistical methods in human genetics. In: Statistics in Genetics: IMA Volume 112 in Mathematics and its Applications Halloran, M. K. and Geisser, S. (eds), pp. 147-104.
5. Hartl, D. L. & Maruyama, T. (1968). Phenogram enumeration: The number of regular genotype-phenotype correspondences in genetic systems. J. Theoret. Biol. 20, 129-103.
6. Huang, J. & and Jiang, V. (1999). Linkage detection adaptive to linkage disequilibrium: The diseqilibrimn maximum-likelihood-binomial test for affeeted-sibship data. Am. J. Hum. Genet. 65, 1741-1759.
7. Lunetta, K. L., Faraone, S. V., Biererman, J. & Laird, N. M. (2000). Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions. Am. J. Hum. Genet. 66, 605-614.
8. McCullagh, P. & Nelder, J. A. (1989). Generalized Linear Models, 2nd edn, Chapman & Hall, London.
9. Morris, A. & Whittaker, J. (1999). Generalization of the extended transmission disequilibrium test to two unlinked disease loci. In: Goldin, L., Amos, C. I., Chase, G. A., Goldstein, A. M., Jarvik, G. P., Martinez, M. M., Suarez, B. K., Weeks, D. W., Wijsinan, E. M., and MacCluer, J. W. Genetic Analysis Workshop 11: Analysis of genetic and environmental factors in common diseases. Genet. Epidemiol., 17 (Suppl. 1), S661-S666.
10. Muller-Myhsok, B. & Abel, L. (1997). Genetic analysis of complex diseases. Science 275, 1328-1329.
11. Persico, A. M., Militerni, R., Bravaccio, C., Schneider, C., Melmed, R., Conciatori, M., Damiani, V., Baldi, A. & Keller, F. (2000). Lack of association between serotonin transporter gene promoter variants and autistic disorder in two ethnically distinct samples. Am. J. Med. Genet. 96, 123-127.
12. Zhao, H. (1999). The interpretation of the parameters in the Transmission/ Disequilibrium test. Am. J. Hum. Genet. 64, 326-328.