In vivo and in vitro effects of lysine clonixinate on nitric oxide synthase in LPS-treated and untreated rat lung preparations

Nitric Oxide - Biology and Chemistry

Volumn 5, Issue 2, 2001, Pages 150-157

  Franchi, A M ^a   Di Girolamo, G ^b   Farina, M ^a   De los Santos, A R ^c   Marti M L ^c   Gimeno, M A F ^a  

^a Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c HOSPITAL DE CLÍNICAS JOSÉ DE SAN MARTÍN   (Argentina)

Author keywords

Indomethacin; iNOS; Lysine clonixinate; Rat lung

Indexed keywords

CLONIXIN LYSINE; INDOMETACIN; NITRIC OXIDE SYNTHASE; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT; WESTERN BLOTTING;

ANIMALIA;

EID: 0035707116     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1006/niox.2000.0325     Document Type: Article

References (25)

1. Selectivity of nonsteroidal anti-inflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
2. Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozyme by aspirin and other nonsteroidal anti-inflammatory drugs
3. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
4. Nitric oxide synthase: Aspects concerning structure and catalysis
5. The emerging multifaceted roles of nitric oxide
6. Nonsteroidal anti-inflammatory drugs inhibit expression of the inducible nitric oxide synthase gene
7. Gastrointestinal blood loss induced by three different nonsteroidal anti-inflammatory drugs
8. Lysine clonixinate versus aspirin in the treatment of gonarthrosis
9. Effects of lysine clonixinate on cyclooxygenase I and II in rat lung and stomach preparations
10. 2 production by vascular smooth muscle cells
11. Regulation of prostacyclin synthesis by the release of endogenous nitric oxide in response to bacterial lipopolysaccharide
12. Regulation of prostaglandin production by nitric oxide in rat smooth muscle myometrial cells
13. Role of nitric oxide in eicosanoid synthesis and uterine motility in estrogen-treated rat uterus
14. Ibuprofen: Effect on inducible nitric oxide synthase
15. Nitric oxide I. Physiological chemistry of nitric oxide and its metabolites: Implications in inflammation
16. Altered immune responses in mice lacking inducible nitric oxide synthase
17. Gases as biological messengers: Nitric oxide and carbon monoxide in the brain
18. Alzheimer's disease with nonsteroidal anti-inflammatory and histamine blocking drugs
19. Do nonsteroidal anti-inflammatory drugs decrease the risk of Alzheimer's disease? The Rotterdam study
20. The advent of highly selective inhibitors of cyclooxygenase. A review
21. Ex vivo effects of lysine clonixinate on cyclooxygenase in rat lung and stomach preparations
22. Efecto del clonixinato de lisina y la indometacina sobre la actividad de la lipoxigenasa y la ciclooxigenasa de colon aislado de pacientes con neoplasias
23. Efecto del clonixinato de lisina sobre la lipoxigenasa y la ciclooxigenasa en vesículas biliares de pacientes con litiasis
24. Nitric oxide activated cyclooxygenase enzymes
25. 2 release from the hypothalamus