Angiogenesis and hereditary hemorrhagic telangiectasia: Rendu-Osler-Weber disease

Acta Haematologica

Volumn 106, Issue 4, 2001, Pages 214-219

  Sabbà, Carlo ^a   Cirulli, Anna ^a   Rizzi, Rita ^a   Pasculli, Giovanna ^a   Gallitelli, Mauro ^a   Specchia, Giorgina ^a   Liso, Vincenzo ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

Angiogenesis; Rendu Osler Weber disease; Telangiectasia

Indexed keywords

CANCER GROWTH FACTOR; ENDOGLIN; VASCULOTROPIN;

ANGIODYSPLASIA; ANGIOGENESIS; ARTICLE; BLEEDING; DIABETES MELLITUS; DISEASE SEVERITY; GENETIC DISORDER; HUMAN; INFLAMMATORY DISEASE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RENDU OSLER WEBER DISEASE; SIGNAL TRANSDUCTION;

ACTIVIN RECEPTORS, TYPE I; ACTIVIN RECEPTORS, TYPE II; ANIMALS; ANTIGENS, CD; ENDOTHELIAL GROWTH FACTORS; GROWTH SUBSTANCES; HUMANS; LYMPHOKINES; NEOVASCULARIZATION, PATHOLOGIC; RECEPTORS, CELL SURFACE; TELANGIECTASIA, HEREDITARY HEMORRHAGIC; TRANSFORMING GROWTH FACTOR BETA; VASCULAR CELL ADHESION MOLECULE-1; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0035706585     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000046618     Document Type: Article

References (48)

1. Mechanism of angiogenesis
2. Angiogenesis in cancer, vascular rheumatoid and other disease
3. Clinical applications of research on angiogenesis
4. Positive and negative regulation of angiogenesis: From cell biology to the clinic
5. Hereditary hemorrhagic telangiectasia
6. Age-related clinical profile of hereditary hemorrhagic telangiectasia in an epidemiologically recruited population
7. Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1
8. Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2
9. Hereditary haemorrhagic telangiectasia with extensive liver involvement is not caused by either HHT1 or HHT2
10. Transforming growth factor-beta: Vasculogenesis, angiogenesis, and vessel wall integrity
11. Inherited diseases of the vasculature
12. Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions
13. Antibody-directed targeting of the vasculature of solid tumors
14. Irradiation induces upregulation of E9 protein (CD105) in human vascular endothelial cells
15. A monoclonal antibody detects heterogeneity in vascular endothelium of tumours and normal tissues
16. Endoglin is an accessor protein that interacts with the signaling receptor complex of multiple members of transforming growth factor-β superfamily
17. Genetic abnormalities in hereditary hemorrhagic telangiectasia
18. Mutant endoglin in hereditary hemorrhagic telangiectasia type 1 is transiently expressed intracellularly and is not a dominant negative
19. Defective angiogenesis in mice lacking endoglin
20. A murine model of hereditary hemorrhagic telangiectasia
21. Characterization of endoglin and identification of novel mutations in hereditary hemorrhagic telangiectasia
22. Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors
23. Activin receptor-like kinases: A novel subclass of cell-surface receptors with predicted serine/threonine kinase activity
24. A novel type I receptor serine-threonine kinase predominantly expressed in the adult central nervous system
25. Assignment of transforming growth factor beta1 and beta3 and a third new ligand to the type I receptor ALK-1
26. SMADs: Mediators and regulators of TGF-beta signaling
27. A transforming growth factor beta type I receptor that signals to activate gene expression
28. Type I receptor serine-threonine kinase preferentially expressed in pulmonary blood vessels
29. Expression of ALK-1, a type 1 serine/threonine kinase receptor, coincides with sites of vasculogenesis and angiogenesis in early mouse development
30. Specific binding of endocrine transforming growth factor-beta 1 to vascular endothelium
31. Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis
32. Blood vessel formation: What is its molecular basis?
33. Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knockout mice
34. Transforming growth factor-beta 3 is required for secondary palate fusion
35. Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction
36. Hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations: Issues in clinical management and review of pathogenic mechanisms
37. Genetic and molecular pathogenesis of hereditary hemorrhagic telangiectasia
38. Biphasic effect of transforming growth factor-beta 1 on in vitro angiogenesis
39. Assignment of transforming growth factor beta1 and beta3 and a third new ligand to the type I receptor ALK-1
40. Physiological consequences of loss of plasminogen activator gene function in mice
41. Hereditary hemorrhagic telangiectasia: A model for blood vessel growth and enlargement
42. Ultrastructure and three-dimensional organization of the telangiectases of hereditary hemorrhagic telangiectasia
43. Expression of vascular endothelial growth factor in pediatric and adult cerebral arteriovenous malformations: An immunocytochemical study
44. Tie endothelial cell-specific receptor tyrosine kinase is upregulated in the vasculature of arteriovenous malformations
45. The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells
46. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
47. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
48. Endoglin expression is reduced in normal vessels but still detectable in arteriovenous malformations of patients with hereditary hemorrhagic telangiectasia type 1