Transcriptional regulation of type I collagen gene

Connective Tissue

Volumn 33, Issue 4, 2001, Pages 285-289

  Ihn, Hironobu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

CCAAT (CBF); Smad; Sp 1; Sp 3; Transforming growth factor (TGF) ; Type I collagen

Indexed keywords

CCAAT BINDING FACTOR; CIS ACTING ELEMENT; COLLAGEN TYPE 1; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ONCOSTATIN M; SMAD PROTEIN; TRANS ACTING FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

FIBROBLAST; FIBROSIS; HUMAN; NONHUMAN; PROTEIN EXPRESSION; REVIEW; TRANSCRIPTION REGULATION;

EID: 0035700593     PISSN: 0916572X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (43)

1. The family of collagen genes
2. Complex and diversified regulatory programs control the expression of vertebrate collagen gene
3. Structurally distinct collagen types
4. Analysis of the promoter region and the N-propeptide domain of the human pro α2(I) collagen gene
5. Functional analysis of cis-acting DNA sequences controlling transcription of the human type I collagen gene
6. Characterization of a GC-rich region containing Sp 1 binding site(s) as a constitutive responsive element of the α2(I) collagen gene in human fibroblasts
7. A nuclear factor I binding site mediates the transcription of a type I collagen promoter by transforming growth factor-β
8. Sp 3 is a transcriptional activator of the human α2(I) collagen gene
9. Competition analysis of the human α2(I) collagen promoter using synthetic oligonucleotides
10. Transcriptional regulation of the human α2(I) collagen gene: Combined action of upstream stimulatory and inhibitory cis-acting elements
11. Selective activation of transcription by a novel CCAAT binding factor
12. Regulation of the human α2(I) collagen gene by sequences adjacent to the CCAAT box
13. Oncostatin M stimulates transcription of the human α2(I) collagen gene via the Sp 1/Sp 3-binding site
14. Conservation of binding sites for regulatory factors in the coordinately expressed α1(I) and α2(I) collagen promoters
15. c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin
16. Cloning and characterization of a transcription factor that binds to the proximal promoters of the two mouse type I collagen genes
17. Transforming growth factor-β stimulates α2(I) collagen gene expression through a cis-acting element that contains an Sp 1-binding site
18. Overlapping pathways mediate the opposing actions of tumor necrosis factor-α and transforming growth factor-β on α2(I) collagen gene transcription
19. Sp 1 is required for the early response of α2(I) collagen to transforming growth factor-β1
20. An AP-1 binding sequence is essential for regulation of the human α2(I) collagen (COL 1 A 2) promoter activity by transforming growth factor-β
21. Stimulation of type I collagen transcription in human skin fibroblasts by TGF-β. Involvement of Smad 3
22. Synergistic cooperation between Sp 1 and Smad 3/Smad 4 mediates transforming growth factor-β1 stimulation of α2(I) collagen gene transcription
23. Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-β involves functional cooperation with p 300/CBP transcriptional coactivators
24. Fli-1 inhibits collagen type I production in dermal fibroblasts via a Sp 1-dependent pathway
25. Nuclear factor-xB mediates TNF-α inhibitory effect on α2(I) collagen gene transcription in human dermal fibroblasts
26. Tumor necrosis factor α inhibits type I collagen synthesis through repressive CCAAT/enhancer binding proteins
27. Tumor necrosis factor-α and interferon-γ suppress the activation of human type I collagen gene expression by transforming growth factor-β1. Evidence for two distinct mechanisms of inhibition at the transcriptional and post-transcriptional levels
28. A proximal element within the human α2(I) collagen (COL 1 A 2) promoter, distinct from the tumor necrosis-α response element, mediates transcriptional repression by interferon-γ
29. Antagonistic regulation of type I collagen gene expression by interferon-γ and transforming growth factor-β. Integration at the level of p 300/CBP transcriptional coactivators
30. Oncostatin M stimulates collagen and glycosaminoglycan production by cultured normal dermal fibroblasts: Insensitivity of sclerodermal and keloidal fibroblasts
31. Sp 1 phosphorylation by serum stimulates the human α2(I) collagen gene expression
32. Transcription factor nuclear factor I and Sp 1 interact with murine collagen α1(1) promoter
33. cKrox binds to several sites in the promoter of both mouse type I collagen genes
34. LAP (NF-IL 6) transactivates the collagen α1(I) gene from a 5′ regulatory region
35. Increased α1(I) procollagen gene expression in tight skin (TSK) mice myocardial fibroblasts is due to a reduced interaction of a negative regulatory sequence with AP-1 transcription factor
36. Binding of upstream stimulatory factor to an E-box in the 3′-flanking region stimulates α1(I) collagen gene transcription
37. Positive regulation of human α1(I) collagen promoter activity by transcription factor Sp 1
38. Increased phosphorylation of transcription factor Sp 1 in scleroderma fibroblasts: Association with increased expression of type I collagen gene
39. Blockade of endogenous transforming growth factor β signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: Association with increased expression of transforming growth factor β receptors
40. Identification of elements in the promoter region of the α1(I) collagen gene involved in its up-regulated expression in systemic sclerosis
41. Regulation of the α2(I) collagen gene transcription in fat-storing cells derived from a cirrhotic liver
42. Activation of Ito cells involves regulation of AP-1 binding proteins and induction of type I collagen gene expression
43. Sp 1 binding activity increased in activated Ito cells