A proximal element within the human α2(I) collagen (COL1A2) promoter, distinct from the tumor necrosis factor-α response element, mediates transcriptional repression by interferon-γ

Matrix Biology

Volumn 16, Issue 8, 1998, Pages 447-456

  Higashi, Kiyoshi ^a   Kouba, David J ^a   Song, Ying Jie ^a   Uitto, Jouni ^a   Mauviel, Alain ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Cytokines; Gene expression; Interferon ; Promoter activity; Type I collagen

Indexed keywords

COLLAGEN; CYTOKINE; GAMMA INTERFERON; PYRIMIDINE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CROSS LINKING; DNA PROTEIN COMPLEX; DOWN REGULATION; FIBROBLAST CULTURE; GENE DELETION; GENE EXPRESSION REGULATION; GENE MAPPING; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; SKIN FIBROBLAST; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 0031913727     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(98)90016-6     Document Type: Article

References (34)

1. Abergel, R.P., Chu, M.L., Bauer, F.A. and Uitto, J.: Regulation of collagen gene expression in cutaneous diseases with dermal fibrosis: evidence for pretranslational control. J. Invest. Dermatol. 88: 727-731, 1987.
2. Andrews, N.C. and Faller, D.V.: A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19: 2499, 1991.
3. Bernstein, E.F., Mauviel, A., MacGrath, J., Franck, T., Bolton, L. and Uitto, J.: Wound Healing. In: Textbook of Cutaneous Surgery, ed. by Lask, G. and Moy, R., 1996, pp. 1-22.
4. Boast, S., Su, M.W., Ramirez, F., Sanchez, M. and Avvcdimento, F.V.: Functional analysis of cis-acting DNA sequences controlling transcription of the human type I collagen genes. J. Biol. Chem. 265: 13351-13356, 1990.
5. Broekelmann, T.J., Limper, A.H., Colby, T.V. and McDonald, J.A.: Transforming growth factor-β1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc. Natl. Acd. Sci. USA 88: 6642-6646, 1991.
6. Chodosh, L.A., Carthew, R.W. and Sharp, P.A.: A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor. Mol. Cell. Biol. 6: 4723-4733, 1986.
7. Chung, K.-Y., Agarwal, A., Uitto, J. and Mauviel, A.: An AP-1 binding sequence is essential for regulation of the human α2(I) collagen (COL1A2) promoter activity by transforming growth factor-β. J. Biol. Chem. 271: 3272-3278, 1996.
8. Dignam, J.D., Martin, P.L., Shastry, B.S. and Roeder, R.G.: Eukaryotic gene transcription with purified components. Meth. Enzymol. 101: 582-598, 1983.
9. Duncan, M.R. and Herman, B.: γ-Interferon is the lymphokine and β-interferon the monokine responsible for inhibition of fibroblast collagen production and late but not early fibroblast proliferation. J. Exp. Med. 162:516-527, 1985.
10. Galera, P., Park, R.W., Ducy, P., Mattei, M.G. and Karsenty, G.: c-Krox binds to several sites in the promoter of both mouse type I collagen genes. Structure/function study and developmental expression analysis. J. Biol. Chem. 271: 21331-21339, 1996.
11. Graham, F. and Van der Eb, A.: Transformation of rat cells by DNA of human adenovirus 5. Virology 52: 456-457, 1973.
12. Gorman, C.M., Moffat, L.F. and Howard, B.H.: Recombinant genomes which express chloramphenicol acetyl transferase in mammalian cells. Mol. Cell Biol. 2: 1044-1051, 1982.
13. Hein, R., Behr, J., Hundgen, M., Hunzelmann, N., Meurer, M., Braun-Falco, O., Urbanski, A. and Krieg, T.: Treatment of systemic sclerosis with γ-interferon. Brit. J. Derm. 126: 496-501, 1992.
14. Heino, J. and Heinonen T.: Interleukin-1β prevents the stimulatory effect of transforming growth factor-β on collagen gene expression in human skin fibroblasts. Biochem. J. 271: 827-830, 1990.
15. Ignotz, R.A. and Massagué, J.: Transforming growth factor-β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J. Biol. Chem. 261: 4337-4345, 1986.
16. Ihn, H., Ohnishi, K., Tamaki, T., LeRoy, E.G. and Trojanowska, M.: Transcriptional regulation of the human α2(I) collagen gene. Combined action of upstream stimulatory and inhibitory cis-acting elements. J. Biol. Chem. 271: 26717-26723, 1996.
17. Kähäri, V.-M., Chen, Y.Q., Su, M.W., Ramirez, F. and Uitto, J.: Tumor necrosis factor-α and interferon-γ suppress the activation of human type I collagen gene expression by transforming growth factor-β. J. Clin. Invest. 86: 1489-1495, 1990.
18. Massagué, J.: The transforming growth factor-beta family. Annu. Rev. Cell. Biol. 6: 597-641, 1990.
19. Matrisian, L.M.: Matrix metalloproteinase gene expression. Ann. NY Acad. Sci. 732:42-50, 1994.
20. Mauviel, A.: Cytokine regulation of metalloproteinase gene expression. J. Cell. Biochem. 53: 288-295, 1993.
21. Mauviel, A., Chen, Y.Q., Dong, W., Evans, C.H. and Uitto, J.: Transcriptional interactions of transforming growth factor-β (TGF-β) with pro-inflammatory cytokines. Curr. Biol. 3: 822-831, 1993.
22. Mauviel, A., Chung, K.Y., Agarwal, A., Tamai, K. and Uitto, J. Cell-specific induction of distinct oncogenes of the Jun family is responsible for differential regulation of collagenase gene expression by transforming growth factor-β in fibroblasts and keratinocytes. J. Biol. Chem. 271: 10917-109223, 1996
23. Mauviel, A., Heino, J., Kähäri, V.-M., Hartmann, D.J., Loyau, G. Pujol, J.-P. and Vuorio, E.: Comparative effects of interleukin-1 and tumor necrosis factor-α on collagen production and corresponding procollagen mRNA levels in human dermal fibroblasts. J. Invest. Dermatol. 96: 243-249, 1991.
24. Mauviel, A. and Uitto, J.: The extracellular matrix in wound healing: Role of the cytokine network. Wounds 5: 137-152, 1993.
25. Nakatsukasa, H., Evarts, R.P., Hsia, C.C. and Thorgeirsson, S.S.: Transforming growth factor-beta 1 and type I procollagen transcripts during regeneration and early fibrosis of rat liver. Lab. Invest. 63: 171-180, 1990.
26. Peltonen, J., Kähäri, L., Jaakkola, S., Kähäri, V.M., Varga, J., Uitto, J. and Jimenez, S.A.: Evaluation of transforming growth factor-β and type I procollagen gene expression in fibrotic skin diseases by in situ hybridization. J. Invest. Dermatol. 94: 365-371, 1990.
27. Pierce, G.F. and Mustoe, T.A.: Pharmacologic enhancement of wound healing. Annu. Rev. Med. 46: 467-481, 1993.
28. Pope, J.: Treatment of systemic sclerosis. Curr. Op. Rheum. 5: 792-801, 1993.
29. Prockop, D.J. and Kivirikko, K.I.: Collagens: molecular biology, diseases, and potentials for therapy. Annu. Rev. Biochem. 64: 403-434, 1995.
30. Roberts, A.B., Sporn, M.B., Assoian, R.K., Smith, J.M., Roche, N.S., Wakefield, L.M., Heine, U.I., Liotta, L.A., Falanga, V. and Kehrl, J.H.: Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc. Natl. Acad. Sci. USA 83: 4167-4171, 1986.
31. Rosenbloom, J., Feldman, G., Freundlich, B. and Jimenez, S.: Inhibition of excessive sceroderma fibroblast collagen production by recombinant γ-interferon. Arthritis Rheum. 29: 851-856, 1986.
32. Sambrook, J., Fritsch, E.F. and Maniatis, T.: Molecular Cloning: A laboratory manual, 2nd ed., Cold Spring Harbor Laboratory Press, 1989.
33. Scharffetter, K., Heckmann, M., Hatamochi, A., Mauch, C., Stein, B., Riethmuller, G., Ziegler-Heitbrock, H.W. and Krieg, T.: Synergistic effect of tumor necrosis factor-α and interferon-γ on collagen synthesis of human skin fibroblasts in vitro. Exp. Cell Res. 181: 409-419, 1989.
34. Varga, J., Olsen, A., Herhal, J., Constantine, G., Rosenbloom, J. and Jimenez, S.A.: Interferon-gamma reverses the stimulation of collagen but not fibronectin gene expression by transforming growth factor-beta in normal human fibroblasts. Eur. J. Clin. Invest. 20: 487-493, 1990.