Endothelin blockade in angiotensin II hypertension: Prevention and treatment studies in the rat

Clinical and Experimental Pharmacology and Physiology

Volumn 28, Issue 12, 2001, Pages 1100-1103

  Ficai, Sylvia ^a   Herizi, Abderraouf ^a   Mimran, Albert ^a   Jover, Bernard ^a  

^a UNIV MONTPELLIER   (France)

Author keywords

Cardiac hypertrophy; Endothelin antagonist; Hypertension

Indexed keywords

ANGIOTENSIN; BOSENTAN; ENDOTHELIN RECEPTOR ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY WALL; BLOOD PRESSURE; BODY WEIGHT; CALCULATION; CAROTID ARTERY; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE COURSE; DISEASE DURATION; DRUG INFUSION; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; HYPERTENSION; HYPOTHESIS; NONHUMAN; OSMOTIC PUMP; RAT;

ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; BODY WEIGHT; CAROTID ARTERIES; HYPERTENSION; MALE; MYOCARDIUM; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ENDOTHELIN; SULFONAMIDES;

EID: 0035684464     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2001.03568.x     Document Type: Conference Paper

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3. Angiotensin II induces fibronectin expression associated with cardiac fibrosis in the rat
4. Endothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensin II-induced hypertrophy in cultured rat cardiomyocytes
5. Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle
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14. Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist
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16. Effect of an endothelin antagonist on hemodynamic responses to angiotensin II
17. Endothelin-1 is involved in norepinephrine-induced ventricular hypertrophyin vivo. Acute effects of bosentan, an orally active, mixed endothelin ETA and ETB receptor antagonist
18. Effect of chronic treatment of adult spontaneously hypertensive rats with an endothelin receptor antagonist
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