Modulation of the multidrug-resistance phenotype by new tropane alkaloid aromatic esters from Erythroxylum pervillei

Journal of Natural Products

Volumn 64, Issue 12, 2001, Pages 1514-1520

  Silva, Gloria L ^a,f   Cui, Baoliang ^a,g   Chávez, Daniel ^a,h   You, Min ^a,i   Chai, Hee Byung ^a   Rasoanaivo, Philippe ^b   Lynn, Sean M ^c   O'Neill, Melanie J ^c   Lewis, Jane A ^c   Besterman, Jeffrey M ^d,j   Monks, Anne ^e   Farnsworth, Norman R ^a   Cordell, Geoffrey A ^a   Pezzuto, John M ^a   Kinghorn, A Douglas ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b INSTITUT MALGACHE DE RECHERCHES APPLIQUÉES   (Madagascar)

^c GLAXOSMITHKLINE   (United Kingdom)

^d GLAXOSMITHKLINE   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

^f UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^g Pure World Botanicals   (United States)

^h TIJUANA INSTITUTE OF TECHNOLOGY   (Mexico)

ⁱ INDIANA UNIVERSITY   (United States)

^j METHYLGENE INC   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; DOXORUBICIN; GLYCOPROTEIN P; PERVILLEINE A; PERVILLEINE B; PERVILLEINE C; PERVILLEINE D; PERVILLEINE E; PERVILLEINE F; TROPANE 3ALPHA,6BETA,7BETA TRIOL 3 PHENYLACETATE; UNCLASSIFIED DRUG; VINBLASTINE;

ADENOCARCINOMA; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; ERYTHROXYLUM PERVILLEI; HUMAN; HUMAN CELL; MOLECULAR MODEL; MULTIDRUG RESISTANCE; PHENOTYPE; PLANT ROOT; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY ANALYSIS; X RAY CRYSTALLOGRAPHY;

ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CRYSTALLOGRAPHY, X-RAY; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG SCREENING ASSAYS, ANTITUMOR; ERYTHROXYLACEAE; ESTERS; FEMALE; HUMANS; MADAGASCAR; MEDICINE, TRADITIONAL; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OVARIAN NEOPLASMS; P-GLYCOPROTEINS; PLANT ROOTS; PLANTS, MEDICINAL; SPECTROPHOTOMETRY, INFRARED; STEREOISOMERISM; TROPANES; TUMOR CELLS, CULTURED;

ERYTHROXYLUM;

EID: 0035684289     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np010295+     Document Type: Article

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