Topotecan induces caspase-dependent apoptosis in HL-60 cells

Chinese Pharmacological Bulletin

Volumn 17, Issue 6, 2001, Pages 650-653

  Chen, Xie Qun ^a   Wan, You Feng ^a   Cao, Yun Xin ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Caspase; HL 60 cells; Topotecan

Indexed keywords

CASPASE; CASPASE 3; CASPASE 8; CASPASE INHIBITOR; PHOSPHATIDYLSERINE; TOPOTECAN;

APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; SURVIVAL RATE;

EID: 0035680813     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Results of topotecan-based combination therapy in patients with myelodysplastic syndromes and chronic myelomonocytic leukemia
2. Combination of topotecan with cytarabine or etoposide in patients with refractory or relapsed acute myeloid leukemia: Results of a randomized phase I/II study
3. Induction of apoptosis by topotecan: Implications for the treatment of leukemia
4. Review: Biochemical and genetic control of apoptosis: Relevance to normal hematopoiesis and hematological malignancies
5. The biochemistry of apoptosis
6. Comparison of apoptosis in wild-type and Fas-resistant cells: Chemotherapy-induced apoptosis is not dependent on fas/fas ligand interaction
7. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
8. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
9. Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis
10. Molecular ordering of apoptosis induced by anticancer drugs in neuroblastoma cells
11. Anticancer drugs induce caspase-8/FLICE activation and apoptosis in the absence of CD95 receptor/ligand interaction
12. Purified photoproducts of merocyanine 540 trigger cytochrome C release and caspase-8 dependent apoptosis in human leukemia and melanoma cells