Feasibility of assessment of promoter methylation of the CD44 gene in serum of prostate cancer patients

Molecular Urology

Volumn 5, Issue 4, 2001, Pages 199-203

  Vis, A N ^a   Oomen, M ^a   Schroder F H ^a   Van Der Kwast, T H ^a  

^a JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HERMES ANTIGEN;

ARTICLE; CANCER DIAGNOSIS; CLINICAL ARTICLE; COLON MUCOSA; CONTROLLED STUDY; CPG ISLAND; DIAGNOSTIC PROCEDURE; DNA METHYLATION; FEASIBILITY STUDY; HUMAN; MALE; MEASUREMENT; METASTASIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CANCER; PROSTATE EPITHELIUM; PROTEIN BLOOD LEVEL; RECTUM MUCOSA; TUMOR SUPPRESSOR GENE;

EID: 0035676838     PISSN: 10915362     EISSN: None     Source Type: Journal    
DOI: 10.1089/10915360152745894     Document Type: Article

References (23)

1. Decreased levels of CD44 protein and mRNA in prostate carcinoma: Correlation with tumor grade and ploidy
2. CD44 and CD44v6 downregulation in clinical prostatic carcinoma: Relation to Gleason grade and cytoarchitecture
3. Prognostic value of cell cycle proteins p27 (kip1) and MIB-1, and the cell adhesion protein CD44s in surgically treated patients with prostate cancer
4. The prognostic value of CD44 isoforms in prostate cancer patients treated by radical prostatectomy
5. Expression and prognostic value of CD44 standard and variant v3 and v6 isoforms in prostate cancer
6. Correlation of p34cdc2 cyclin-dependent kinase overexpression, CD44s downregulation, and HER-2/neu oncogene amplification with recurrence in prostatic adenocarcinomas
7. Decreased expression of CD44 in metastatic prostate cancer
8. CD44 is a metastasis suppressor gene for prostatic cancer located on human chromosome 11p13
9. Down-regulation of CD44 expression in human prostatic carcinoma cell lines is correlated with DNA hypermethylation
10. Methylation of the CD44 metastasis suppressor gene in human prostate cancer
11. Silencing of CD44 expression in prostate cancer by hypermethylation of the CD44 promoter region
12. E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas
13. Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
14. Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients
15. Detection of aberrant p16 methylation in the plasma and serum of liver cancer patients
16. Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
17. Microsatellite alterations in serum DNA of head and neck cancer patients
18. X chromosome imprinting and inactivation in the early mammalian embryo
19. Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
20. CpG island methylator phenotype in colorectal cancer
21. Analysis of anomalous CD44 gene expression in human breast, bladder, and colon cancer and correlation of observed mRNA and protein isoforms
22. Normal human tissues, in addition to some tumors, express multiple different CD44 isoforms
23. Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression