Association of clonal T-cell large granular lymphocyte disease and paroxysmal nocturnal haemoglobinuria (PNH): Further evidence for a pathogenetic link between T cells, aplastic anaemia and PNH

British Journal of Haematology

Volumn 115, Issue 4, 2001, Pages 1010-1014

  Karadimitris, Anastasios ^a,b   Li, Ke ^a   Notaro, Rosario ^a,d   Araten, David J ^a   Nafa, Khedoudja ^a   Thertulien, Raymond ^a   Ladanyi, Marc ^a   Stevens, Ann E ^c   Rosenfeld, Calvin S ^a   Roberts, Irene A G ^b   Luzzatto, Lucio ^a,d  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF GENOA   (Italy)

Author keywords

Paroxysmal nocturnal haemoglobinuria; T cell clones; T cell large granular lymphocyte disease

Indexed keywords

CYCLOPHOSPHAMIDE; T LYMPHOCYTE RECEPTOR;

ADULT; ANTIGENICITY; APLASTIC ANEMIA; ARTICLE; BETA CHAIN; CASE REPORT; DISEASE ASSOCIATION; FEMALE; GENE SEQUENCE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LYMPHOCYTE CLONE; LYMPHOCYTE PROLIFERATION; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PATHOGENESIS; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

ADULT; ANEMIA, APLASTIC; CELL DIVISION; CLONE CELLS; COCULTURE TECHNIQUES; FEMALE; GENE REARRANGEMENT, BETA-CHAIN T-CELL ANTIGEN RECEPTOR; HEMATOPOIETIC STEM CELLS; HEMOGLOBINURIA, PAROXYSMAL; HUMANS; LEUKEMIA, T-CELL; POLYMERASE CHAIN REACTION; T-LYMPHOCYTES;

EID: 0035673393     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.03172.x     Document Type: Article

References (23)

1. Pure red cell aplasia. Lymphocyte inhibition of erythropoiesis
2. Myelodysplastic syndrome and aplastic anemia: Distinct entities or diseases linked by a common pathophysiology?
3. Oligoclonality of CD8+ T cells in health and disease: Aging, infection, or immune regulation?
4. Circulating hematopoietic progenitor cells in first trimester fetal blood
5. Clinical spectrum of clonal proliferations of T-large granular lymphocytes: A T-cell clonopathy of undetermined significance?
6. CD30 (Ki-1)-positive malignant lymphomas: Clinical, immunophenotypic, histologic, and genetic characteristics and differences with Hodgkin's disease
7. Lymphoproliferative disease of granular T lymphocytes presenting as aplastic anemia
8. Pure red-cell aplasia associated with clonal expansion of granular lymphocytes expressing killer-cell inhibitory receptors
9. Determination of neutrophil antigen gene frequencies in five ethnic groups by polymerase chain reaction with sequence-specific primers
10. The cellular pathogenesis of paroxysmal nocturnal haemoglobinuria
11. Abnormal T-cell repertoire is consistent with immune process underlying the pathogenesis of paroxysmal nocturnal hemoglobinuria
12. Current concepts: Large granular lymphocyte leukemia
13. Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients
14. Anergy and apoptosis in CD8+ T cells from HIV-infected persons
15. Haematological response of patients with myelodysplastic syndrome to antithymocyte globulin is associated with a loss of lymphocyte-mediated inhibition of CFU-GM and alterations in T-cell receptor Vbeta profiles
16. Clinical characteristics predict response to antithymocyte globulin in paroxysmal nocturnal haemoglobinuria
17. Paroxysmal nocturnal haemoglobinuria
18. Coincident myelodysplastic syndrome and T-cell large granular lymphocytic disease: Clinical and pathophysiological features
19. The lymphoproliferative disease of granular lymphocytes: Updated criteria for diagnosis
20. Analysis of TCR rearrangements using inverse-PCR
21. The problem of clonality in aplastic anemia. Dr Dameshek's riddle, restated
22. The treatment of severe acquired aplastic anemia
23. Characterization of T-cell repertoire of the bone marrow in immune-mediated aplastic anemia evidence for the involvement of antigen-driven T-cell response in cyclosporine-dependent aplastic anemia