A new level of regulation in transcription elongation?

Trends in Biochemical Sciences

Volumn 26, Issue 12, 2001, Pages 695-697

  Sousa, Rui ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR; NUCLEOTIDE TRIPHOSPHATE; PHOSPHATE; RNA POLYMERASE; UNCLASSIFIED DRUG;

DNA TEMPLATE; GENE CONTROL; GENETIC TRANSCRIPTION; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STRUCTURE; SHORT SURVEY; TIME; TRANSCRIPTION REGULATION;

EID: 0035664079     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(01)02000-X     Document Type: Review

References (22)

1. Allosteric binding of nucleoside triphosphates to RNA polymerase regulates transcription elongation
2. Single molecule study of transcriptional pausing and arrest by E. coli RNA polymerase
3. Shifting RNA polymerase into overdrive
4. Mechanism of intrinsic transcription termination and anti-termination
5. Termination of transcription by Escherichia coli RNA polymerase in vitro. Effect of altered reaction conditions and mutations in the enzyme protein on termination with T7 and T3 deoxyribonucleic acids
6. Mapping and characterization of transcriptional pause sites in the early genetic regions of bacteriophage T7
7. Nonequilibrium mechanisms of transcription termination from observations of single RNA polymerase molecules
8. Pausing by bacterial RNA polymerase is mediated by mechanistically distinct classes of signals
9. Roles of RNA:DNA hybrid stability, RNA structure, and activated site conformation in pausing by human RNA polymerase II
10. Molecular biology. Running the red light
11. RNA polymerase switches between inactivated and activated states by translocating back and forth along the DNA and RNA
12. The RNA:DNA hybrid maintains the register of transcription by preventing back-tracking of RNA polymerase
13. A model for the mechanism of polymerase translocation
14. T7 RNA polymerase elongation complex structure and movement
15. Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 Å resolution
16. Structural basis of transcription: An RNA polymerase II elongation complex at 3.3 Å resolution
17. Transcription by single molecules of RNA polymerase observed by light microscopy
18. Pausing and termination of transcription within the early region of bacteriophage T7 DNA in vitro
19. Structure of a transcribing T7 RNA polymerase initiation complex
20. Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution
21. Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: Structural basis for nucleotide incorporation