A new translational repression element and unusual transcriptional control regulate expression of don juan during Drosophila spermatogenesis

Mechanisms of Development

Volumn 110, Issue 1-2, 2002, Pages 97-112

  Blümer, Nicole ^a   Schreiter, Kay ^b   Hempel, Leonie ^a   Santel, Ansgar ^a   Hollmann, Martin ^b   Schäfer, Mireille A ^b   Renkawitz Pohl, Renate ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Gene regulation; Male germ cell development; Mst98Ca b; RNA binding proteins; Translational repression and activation

Indexed keywords

RNA BINDING PROTEIN;

5' UNTRANSLATED REGION; ARTICLE; ASSAY; CONTROLLED STUDY; CROSS LINKING; DROSOPHILA; ENZYME ACTIVATION; ENZYME REPRESSION; GENE EXPRESSION; GENETIC REGULATION; GENETIC TRANSCRIPTION; MEIOSIS; MORPHOGENESIS; MULTIGENE FAMILY; MUTANT; NONHUMAN; OVARY; PRIORITY JOURNAL; PROTEIN BINDING; RNA TRANSLATION; SPERMATOCYTE; SPERMATOGENESIS; TESTIS; ULTRAVIOLET RADIATION;

DROSOPHILA;

EID: 0035663712     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(01)00577-9     Document Type: Article

References (66)

1. A functional ribonucleoprotein complex forms around the 5′ end of poliovirus RNA
2. Genes encoding Drosophila melanogaster RNA polymerase II general transcription factors: Diversity in TFIIA and TFIID components contributes to gene-specific transcriptional regulation
3. Expression of heat-shock locus hsr-omega in nonstressed cells during development in Drosophila melanogaster
4. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
5. Post-transcriptional control of gene expression during spermatogenesis
6. Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters
7. The downstream core promoter element, DPE, is conserved from Drosophila to humans and is recognized by TAFII60 of Drosophila
8. Overlapping but distinct RNA elements control repression and activation of nanos translation
9. Cytoplasmic polyadenylation elements mediate masking and unmasking of cyclinB1 mRNA
10. Tissue-specific microtubule functions in Drosophila spermatogenesis require the β 2-tubulin isotype-specific carboxy terminus
11. Structural analysis of mutations in the Drosophila β2-tubulin isoform reveal regions in the β-tubulin molecule required for general and tissue-specific functions
12. Spermatogenesis
13. Organisation of regulatory elements in two closely spaced Drosophila genes with common expression characteristics
14. Spatial and temporal pattern of hsp26 expression during normal development
15. Preservation of nuclear RNP antigens in male germ cell development of Drosophila hydei
16. Translational repression: Not just a Puf of smoke
17. Translational regulation of maternal RNA
18. Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase
19. Testis/brain RNA-binding protein attaches translationally repressed and transported mRNAs to microtubules
20. Involvement of a tissue-specific RNA recognition motif protein in Drosophila spermatogenesis
21. Association of RB97D, an RRM protein required for male fertility, with a Y chromosome lampbrush loop in Drosophila spermatocytes
22. Developmental regulation of transcription by a tissue-specific TAF homolog
23. Assembly of ring canals in the male germ line from structural components of the contractile ring
24. Improved predictions of secondary structures for RNA
25. During spermatogenesis β 1, β 2 and β 3 tubulin are cell type specifically expressed but have the potential to coassemble into the axoneme of transgenic flies
26. The Rb97D gene encodes a potential RNA-binding protein required for spermatogenesis in Drosophila
27. Gene regulation in Drosophila spermatogenesis: Analysis of protein binding at the translational control element TCE
28. Patterns of translational regulation in the mammalian testis
29. Functional messenger RNAs are produced by SP6 in vitro transcription of cloned cDNAs
30. Cis-acting regions sufficient for spermatocyte-specific transcriptional and spermatid-specific translational control of the Drosophila melanogaster gene mst(3)gl-9
31. A cluster of four genes selectively expressed in the male germ line of Drosophila melanogaster
32. Multifunctional proteins suggest connections between transcriptional and post-transcriptional processes
33. The Drosophila orb gene is predicted to encode sex-specific germline RNA-binding proteins and has localized transcripts in ovaries and early embryos
34. Coordinate developmental control of the meiotic cell cycle and spermatid differentiation in Drosophila males
35. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promotor
36. Translational control by CPEB: A means to the end
37. A 14 bp sequence directs the testis-specific β2 tubulin gene expression in Drosophila
38. Further sequence requirements for male germ cell expression under the control of the 14 bp promoter element (β 2UE1) of the Drosophila β2 tubulin gene
39. An 18 bp element in the 5′ untranslated region regulates the level of the Drosophila β2 tubulin mRNA during postmeiotic stages of spermatogenesis
40. The DNA/RNA-binding protein, TB-RBP, moves from the nucleus to the cytoplasm and through intercellular bridges in male germ cells
41. The Drosophila don juan (dj) gene encodes a novel sperm specific protein component characterized by an unusual domain of a repetitive amino acid motif
42. Flagellar mitochondrial association of the male-specific Don Juan protein in Drosophila spermatozoa
43. The initiator element of the Drosophila β2 tubulin gene core promoter contributes to gene expression in vivo but is not required for male germ line specific expression
44. A conserved element in the leader mediates post-meiotic translation as well as cytoplasmic polyadenylation of a Drosophila spermatocyte mRNA
45. Expression of a gene duplication encoding conserved sperm tail proteins is translationally regulated in Drosophila melanogaster
46. Translational control in spermatogenesis
47. Genes for male-specific transcripts in Drosophila melanogaster
48. Specific binding of a 47-kilodalton protein to the 3′ untranslated region of rat transition protein 2 messenger ribonucleic acid
49. Cis-acting sequences required for the germ line expression of the Drosophila gonadal gene
50. Mechanisms of translational control in early development
51. Transcription factor IIIA (TFIIIA) in the second decade
52. A specific RNA hairpin loop structure binds the RNA recognition motifs of the Drosophila SR protein B52
53. Recruitment of Nanos to hunchback mRNA by Pumilio
54. Maskin is a CPEB-associated factor that transiently interacts with eIF-4E
55. A non radioactive in situ hybridization method for localization of specific RNAs in Drosophila embryos reveals a translational control of the segmentation gene hunchback
56. The IRE (iron regulatory element) family: Structures which regulate mRNA translation or stability
57. Vectors for Drosophila P-element-mediated transformation and tissue culture transfection
58. Awakening dormant mRNAs
59. The roles of RNA-binding proteins in spermatogenesis and male infertility
60. Coaxial stacking of helixes enhances binding of oligoribonucleotides and improves predictions of RNA folding
61. Translational repressor bruno plays multiple roles in development and is widely conserved
62. Transcriptional and post-transcriptional control mechanisms co-ordinate the onset of spermatid differentiation with meiosis I in Drosophila
63. High affinity interaction of dipteran high mobility group (HMG) proteins 1 with DNA is modulated by COOH-terminal regions flanking the HMG box domain
64. Expression of the dihydroorotate dehydrogenase gene, dhod, during spermatogenesis in Drosophila melanogaster
65. Transcriptional and translational cis-regulatory sequences of the spermatocyte-specific Drosophila janusB gene are located in the 3′ exonic region of the overlapping janusA gene
66. Algorithms and thermodynamics for RNA secondary structure prediction: A practical guide