Effects of sulphonylureas on the volume-sensitive anion channel in rat pancreatic β-cells

British Journal of Pharmacology

Volumn 125, Issue 4, 1998, Pages 874-878

  Best, L ^a   Benington, S ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Anion channel; Pancreatic cell; Sulphonylurea; Volume regulation

Indexed keywords

4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; ANION CHANNEL; GLIBENCLAMIDE; MEGLITINIDE; MEMBRANE LIPID; PROTON; SULFONYLUREA; TAURINE; TOLBUTAMIDE;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTRIC ACTIVITY; ION CONDUCTANCE; NONHUMAN; PANCREAS ISLET BETA CELL; PATCH CLAMP; PRIORITY JOURNAL; PROTON TRANSPORT; RAT;

ANIMALS; ANIONS; BENZAMIDES; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EVOKED POTENTIALS; GLYBURIDE; HYPOGLYCEMIC AGENTS; ION CHANNELS; ION TRANSPORT; ISLETS OF LANGERHANS; RATS; SULFONYLUREA COMPOUNDS; TAURINE; TOLBUTAMIDE;

EID: 0031758017     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702148     Document Type: Article

References (15)

1. AGUILAR-BRYAN, L., NICHOLS, C.G., WECHSLER, S.W., CLEMENT, J.P., BOYD, A.E., GONZALEZ, G., HERRERA-SOSA, H., NGUY, K., BRYAN, J. & NELSON, D.A. (1995). Cloning of the β-cell high-affinity sulfonylurea receptor: A regulator of insulin secretion. Science, 268, 423-429.
2. ASHCROFT, F.M. & RORSMAN, P. (1989). Electrophysiology of the pancreatic β-cell. Prog. Biophys. Molec. Biol., 54, 87-143.
3. BEST, L., MILEY, H.E. & YATES, A.P. (1996a). Activation of an anion conductance and β-cell depolarization during hypotonically-induced insulin release. Exp. Physiol., 81, 927-933.
4. BEST, L., SHEADER, E.A. & BROWN, P.D. (1995). A volume-activated anion conductance in insulin-secreting cells. J. Physiol., 489P, 64P.
5. BEST, L., SHEADER, E.A. & BROWN, P.D. (1996b). A volume-activated anion conductance in insulin-secreting cells. Pflugers Arch., 431, 363-370.
6. 3H glibenclamide in pancreatic islet cells. Diabetologia 29, 259-261.
7. DOROSHENKO, P., PENNER, R. & NEHER, E. (1991). Novel chloride conductance in the membrane of bovine chromaffin cells activated by intracellular GTPγS. J. Physiol., 436, 711-724.
8. HENQUIN, J.C. (1990). Established, unsuspected and novel pharmacological insulin secretagogues. In New Antidiabetic Drugs, ed. Bailey, C.J. & Flatt, P.R. pp. 93-106. London: Smith-Gordon.
9. KINARD, T.A. & SATIN, L.S. (1995). An ATP-sensitive Cl channel current that is activated by cell swelling, cAMP and glyburide in insulin-secreting cells. Diabetes, 44, 1461-1466.
10. MANOLOPOULOS, V.G., VOETS, T., DECLERQ, P.E., DROOGMANS, G. & NILIUS, B. (1997). Swelling-activated efflux of taurine and other organic osmolytes in endothelial cells. Am. J. Physiol., 273, C214-C222.
11. OKADA, Y. (1997). Volume expansion-sensing outward-rectifier Cl channel: fresh start to the molecular identity and volume sensor. American Journal of Physiology 273, C755-C789.
12. SEHLIN, J. (1978). Interrelationships between chloride fluxes in pancreatic islets and insulin release. Am. J. Physiol., 235, E501-E508.
13. + channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents. J. Gen. Physiol., 100, 573-591.
14. TSENG, G.-N. (1992). Cell swelling increases membrane conductance of canine cardiac cells: evidence for a volume-sensitive Cl channel. Am. J. Physiol., 262, C1056-C1068.
15. WANGEMANN, P., WITTNER, M., DI STEFANO, A., ENGLERT, H.C., LANG, H.J., SCHLATTER, E. & GREGER, R. (1986). Cl channel blockers in the thick ascending limb of the loop of Henle. Structure activity relationships. Pflugers Arch., 407, S128-S141.