Role of T cells in development of chronic pancreatitis in male Wistar Bonn/Kobori rats: Effects of tacrolimus

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 281, Issue 6 44-6, 2001, Pages

  Yamada, Tamaki ^a,c   Hashimoto, Takashi ^a   Sogawa, Mitsue ^b   Kobayashi, Sawako ^b   Kaneda, Kenji ^a   Nakamura, Soichi ^a   Kuno, Atsushi ^a   Sano, Hitoshi ^a   Ando, Tomoaki ^b   Kobayashi, Shinya ^a   Aoki, Shigeru ^a   Nakazawa, Takahiro ^a   Ohara, Hirotaka ^a   Nomura, Tomoyuki ^b   Takashi, J O H ^a   Itoh, Makoto ^a  

^a NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^b OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Kawasumi   (Japan)

Author keywords

Acinar cells; Apoptosis; Autoimmune pancreatitis; Corticosteone

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; TACROLIMUS;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; CELL FUNCTION; CELL INFILTRATION; CELL PROTECTION; CHRONIC PANCREATITIS; CONNECTIVE TISSUE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DOSE RESPONSE; DRUG EFFECT; HUMAN; MACROPHAGE; MALE; MONOCYTE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; RAT STRAIN; T LYMPHOCYTE;

EID: 0035662128     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.2001.281.6.g1397     Document Type: Article

References (37)

1. IL-1 alpha, IL-gamma, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4+ T lymphocytes
2. Chronic pancreatitis, HLA and autoimmunity
3. Lymphocyte subsets and HLA-DR expression in normal and chronic pancreatitis
4. The effect of FK506 on cyclophosphamide-induced diabetes in the NOD mouse model
5. The role of Fas in autoimmune diabetes
6. Immunomodulator therapy in inflammatory disease
7. HLA antigens in chronic pancreatitis
8. Intrathymic islet cell transplantation reduces beta-cell autoimmunity and prevents diabetes in NOD/Lt mice
9. Assessment of leukocyte involvement during ischemia and perfusion of intestine
10. An immunosuppressant compound, FK-506, prevents the progression of autoimmune myocarditis in rats
11. Apoptosis of acinar cells is involved in chronic pancreatitis in WBN/Kob rats: Role of glucocorticoids
12. Protective effects of gabexate mesilate on acute pancreatitis induced by tacrolimus (FK506) in rats in which the pancreas was stimulated by caerulein
13. Autoimmune pancreatitis as a new clinical entity
14. Expression of major histocompatibility antigens in human chronic pancreatitis
15. Elevated apoptosis of peripheral T lymphocytes in diabetic BB rats
16. Lymphocyte-mediated cytotoxicity in vitro and in vivo: Mechanism and significance
17. Spontaneous development of pancreatitis in the MRL/Mp strain of mice by autoimmune mechanism
18. FK-506, a novel immunosuppressant isolated from Streptomyces I
19. FK-506, a novel immunosuppressant isolated from Streptomyces II
20. Prevention of diabetes in BB/Wor rats by intrathymic islet cell injection
21. Neonatal thymectomy prevents spontaneous diabetes mellitus in the BioBreeding/Worcester rat
22. FK506 potentiates steroid-induced T-cell apoptosis
23. Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in non-obese diabetic mice
24. A new diabetic strain of rat with exocrine pancreatic insufficiency
25. Effect of a novel immunosuppressant, FK-506, on autoimmune glomerulonephritis in Brown Norway rats
26. Inhibitory effect of estrogen on the development of diabetic symptoms in male WBN/Kob rats
27. FK-506 prevents diabetes in diabetic-prone BB/Wor rats
28. WBN/Kob rats. A new spontaneously occurring model of chronic pancreatitis
29. Autoimmune-related pancreatitis is associated with autoantibodies and a Th1/Th2-type cellular immune response
30. Differential ability of Th1 and Th2 cells to express Fas ligand and to undergo activation-induced cell death
31. Chronic inflammatory sclerosing pancreas -autonomous pancreatic disorders
32. Tacrolimus limits polymorphonuclear leukocyte accumulation and protects against ischemia-reperfusion injury
33. CD8+ T cell homing to the pancreas in the non-obese diabetic mouse is CD4+ T cell-dependent
34. Comparative studies on the circadian rhythm of corticosterone lipid and cholesterol levels in adrenals and blood of rats
35. T cell-mediated exocrine pancreatic damage in major histocompatibility complex class II-deficient mouse
36. Effects of FK506 on rat thymic microenvironment in thymocyte maturation, proliferation, and mobilization
37. Chronic pancreatitis caused by an autoimmune abnormality