Our new understanding of pulmonary alveolar proteinosis: What an internist needs to know

Cleveland Clinic Journal of Medicine

Volumn 68, Issue 12, 2001, Pages 977-993

  Mazzone, P ^a   Thomassen, M J ^a   Kavuru, M ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; AMBROXOL; ANTIBIOTIC AGENT; AUTOANTIBODY; CORTICOSTEROID; CYTOKINE ANTIBODY; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEPARIN; INTERLEUKIN 10 ANTIBODY; LUNG SURFACTANT; MUCOLYTIC AGENT; SODIUM CHLORIDE; TRYPSIN;

ADOLESCENT; ADULT; AGED; ANIMAL EXPERIMENT; ANTIBODY DETECTION; AUTOIMMUNE DISEASE; BACTERIAL INFECTION; BONE PAIN; CHILD; CLINICAL FEATURE; DIAGNOSTIC ERROR; DIAGNOSTIC VALUE; ENVIRONMENTAL FACTOR; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPOTENSION; IDIOPATHIC DISEASE; IMMUNOPATHOGENESIS; LUNG ALVEOLUS PROTEINOSIS; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MOUSE; MYALGIA; NONHUMAN; RASH; REVIEW; TREATMENT PLANNING; VIRUS INFECTION;

EID: 0035660012     PISSN: 08911150     EISSN: None     Source Type: Journal    
DOI: 10.3949/ccjm.68.12.977     Document Type: Review

References (51)

1. Pulmonary alveolar proteinosis
2. Pulmonary alveolar proteinosis
3. Pulmonary alveolar proteinosis: Clinical features and outcomes
4. Pulmonary alveolar phospholipoproteinosis: Experience with 34 cases and a review
5. Primary pulmonary alveolar proteinosis. Clinical observation of 68 patients in Japan
6. Morphologic diagnosis of idiopathic pulmonary alveolar lipoproteinosis-revisited
7. Physiologic effects of bronchopulmonary lavage in alveolar proteinosis
8. Pulmonary alveolar proteinosis in four siblings
9. Pulmonary alveolar proteinosis in Israel: Ethnic clustering
10. Pulmonary alveolar proteinosis. Chapter M12
11. Pulmonary alveolar proteinosis: Treatment by massive bronchopulmonary lavage
12. Computed tomography appearances of pulmonary alveolar proteinosis
13. Pulmonary alveolar proteinosis: CT findings
14. Pulmonary alveolar proteinosis: High-resolution, CT, chest radiographic, and functional correlations
15. Pulmonary alveolar proteinosis: Shunt fraction and lactic acid dehydrogenase concentration as aids to diagnosis
16. Clearance and recycling of pulmonary surfactant
17. Effects of proteinosis surfactant proteins on the viability of rat alveolar macrophages
18. Defective lung macrophages in pulmonary alveolar proteinosis
19. Pulmonary alveolar proteinosis: Abnormal in vitro function of alveolar macrophages
20. Macrophage function in pulmonary alveolar proteinosis
21. Pulmonary alveolar proteinosis: Further evaluation of abnormal alveolar macrophages
22. Improvement in alveolar macrophage migration after therapeutic whole lung lavage in pulmonary alveolar proteinosis
23. Pulmonary alveolar proteinosis is a disease of decreased availability of GM-CSF rather than an intrinsic cellular defect
24. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis
25. Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology
26. Surfactant metabolism in transgenic mice after granulocyte macrophage-colony stimulating factor ablation
27. Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice
28. Aerosolized GM-CSF ameliorates pulmonary alveolar proteinosis in GM-CSF deficient mice
29. Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5
30. The pulmonary alveolar proteinosis in granulocyte macrophage colony-stimulating factor/interleukins 3/5 Bc receptor-deficient mice is reversed by bone marrow transplantation
31. Persistence of pulmonary pathology and abnormal lung function in IL-3/GM-CSF/IL-5 common beta receptor-deficient mice despite correction of alveolar proteinosis after BMT
32. Attenuated hematopoietic response to granulocyte-macrophage colony-stimulating factor in patients with acquired pulmonary alveolar proteinosis
33. Exogenous granulocyte-macrophage colony-stimulating factor administration for pulmonary alveolar proteinosis
34. GM-CSF gene expression is normal but protein release is absent in a patient with pulmonary alveolar proteinosis
35. Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression
36. GM-CSF and GM-CSF Bc receptor in adult patients with pulmonary alveolar proteinosis
37. Idiopathic pulmonary alveolar proteinosis as an autoimmune disease with neutralizing antibody against granulocyte/macrophage colony-stimulating factor
38. Serum and lavage lactate dehydrogenase isoenzymes in pulmonary alveolar proteinosis
39. Elevated levels of lung surfactant protein A in sera from patients with idiopathic pulmonary fibrosis and pulmonary alveolar proteinosis
40. Surfactant apoprotein-A concentration in sputum for diagnosis of pulmonary alveolar proteinosis
41. Pulmonary surfactant protein D in sera and bronchoalveolar lavage fluids
42. Spontaneously occurring neutralizing antibodies against granulocyte-macrophage colony-stimulating factor in patients with autoimmune disease
43. Antibody to granulocyte-macrophage colony stimulating factor is a dominant anti-cytokine activity in human IgG preparations
44. Bronchopulmonary lavage in man
45. Alveolar proteinosis treated. Total lung lavage proves successful
46. Advances in the treatment of pulmonary alveolar proteinosis
47. Bronchopulmonary lavage in pulmonary alveolar proteinosis: Chest radiograph observations
48. Pulmonary alveolar proteinosis: Xe-133 scintigraphic findings before and after bronchopulmonary lavage
49. Therapeutic efficacy of granulocyte-macrophage colony-stimulating factor in patients with idiopathic acquired alveolar proteinosis
50. Recurrent alveolar proteinosis following double lung transplantation
51. Pulmonary alveolar proteinosis: Lung transplant or bone marrow transplant