Promiscuous antigen presentation by the nonclassical MHC Ib Qa-2 is enabled by a shallow, hydrophobic groove and self-stabilized peptide conformation

Structure

Volumn 9, Issue 12, 2001, Pages 1213-1224

  He, Xiao Lin ^a   Tabaczewski, Piotr ^b   Ho, Joseph ^a   Stroynowski, Iwona ^b   Garcia, K Christopher ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Immune recognition; MHC; Nonclassical; Structure; X ray crystallography

Indexed keywords

AMINO ACID; HISTIDINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE; PROTEIN QA 2; RIBOSOME PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIGEN PRESENTATION; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CRYSTAL STRUCTURE; GENE STRUCTURE; HYDROPHOBICITY; IMAGE ANALYSIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

ANIMALS; ANTIGEN PRESENTATION; CRYSTALLOGRAPHY, X-RAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENES, MHC CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS I; HYDROGEN BONDING; MICE; MICE, INBRED C57BL; MODELS, MOLECULAR; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPLEEN;

MURINAE;

EID: 0035659338     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00689-X     Document Type: Article

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