메뉴 건너뛰기




Volumn 79, Issue 5, 2001, Pages 507-511

Valency or wählency: Is the epitope diversity of the B-cell response regulated or chemically determined?

Author keywords

Affinity; Antibody; Antigen valency; Fc receptors

Indexed keywords

ANTIBODY; EPITOPE; FC RECEPTOR;

EID: 0035570946     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1711.2001.01021.x     Document Type: Article
Times cited : (8)

References (48)
  • 6
    • 84991249698 scopus 로고
    • The precipitin reaction between type III pneumococcus polysaccharide and homologous antibody. III: A quantitative study and a theory of the reaction mechanism
    • (1935) J. Exp. Med. , vol.61 , pp. 563-591
    • Heidelberger, M.1    Kendall, F.E.2
  • 8
    • 0020041776 scopus 로고
    • The binding of human immunoglobulin G1 monomer and small, covalently cross-linked polymers of immunoglobulin G1 to human peripheral blood monocytes and polymorphonuclear leukocytes
    • (1982) J. Clin. Invest. , vol.69 , pp. 1-8
    • Kurlander, R.J.1    Batker, J.2
  • 10
    • 0030657786 scopus 로고    scopus 로고
    • Neutrophil Fcgamma and complement receptors involved in binding soluble IgG immune complexes and in specific granule release induced by soluble IgG immune complexes
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2514-2523
    • Voice, J.K.1    Lachmann, P.J.2
  • 19
    • 0017345038 scopus 로고
    • 125I-labelled C1q and C1q binders and their use in the measurement of plasma C1q concentrations
    • (1977) Immunology , vol.32 , pp. 191-198
    • Hughes-Jones, N.C.1
  • 22
    • 0025732287 scopus 로고
    • The effect of antibody isotype and antigenic epitope density on the complement-fixing activity of immune complexes: A systematic study using chimaeric anti-NIP antibodies with human Fc regions
    • (1991) Clin. Exp. Immunol. , vol.84 , pp. 1-8
    • Lucisano Valim, Y.M.1    Lachmann, P.J.2
  • 30
    • 0031409779 scopus 로고    scopus 로고
    • An antigen valence theory to explain the evolution and organization of the humoral immune response
    • (1997) Immunol. Cell Biol. , vol.75 , pp. 604-618
    • Hodgkin, P.D.1
  • 33
    • 0026770035 scopus 로고
    • Comparison of immune responses to a native viral antigen and a synthetic peptide derived from it: Implications for vaccine development
    • (1992) Vaccine , vol.10 , pp. 814-816
    • Kumar, A.1    Kaul, S.2    Manivel, V.3    Rao, K.V.4
  • 37
    • 0025781883 scopus 로고
    • Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions
    • (1991) J. Immunol. , vol.147 , pp. 1720-1729
    • Sanz, I.1
  • 38
    • 0022354306 scopus 로고
    • Intrinsic and extrinsic factors in protein antigenic structure
    • (1985) Science , vol.229 , pp. 932-940
    • Berzofsky, J.A.1
  • 40
    • 0031203904 scopus 로고    scopus 로고
    • B cell responses to a peptide epitope: III. Differential T helper cell thresholds in recruitment of B cell fine specificities
    • (1997) J. Immunol. , vol.159 , pp. 1077-1085
    • Agarwal, A.1    Rao, K.V.2
  • 42
    • 0032100706 scopus 로고    scopus 로고
    • Affinity dependence of the B cell response to antigen: A threshold, a ceiling, and the importance of off rate
    • (1998) Immunity , vol.8 , pp. 751-759
    • Batista, F.D.1    Neuberger, M.S.2
  • 44
    • 0014610099 scopus 로고
    • Regulation of antibody formation by serum antibody. I. Removal of specific antibody by means of immuno-adsorption
    • (1969) J. Exp. Med. , vol.130 , pp. 1175-1186
    • Graf, M.W.1    Uhr, J.W.2
  • 45
    • 0015170714 scopus 로고
    • Regulation of the immune response. V. An analysis of the function of the Fc portion of antibody in suppression of an immune response with respect to interaction with components of the lymphoid system
    • (1971) Immunology , vol.21 , pp. 967-981
    • Chan, P.L.1    Sinclair, N.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.