B Cell Responses to a Peptide Epitope: I. The Cellular Basis for Restricted Recognition

Journal of Immunology

Volumn 157, Issue 7, 1996, Pages 2779-2788

  Agarwal, Anshu ^a   Sarkar, Surojit ^a,b   Nazabal, Consuelo ^a,c   Balasundaram, G ^a   Rao, Kanury V S ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY ICGEB   (India)

^b LUPIN LIMITED   (India)

^c CENTER FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Cuba)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MONOCLONAL ANTIBODY; OLIGOPEPTIDE;

AMINO ACID SEQUENCE; ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; B LYMPHOCYTE; BAGG ALBINO MOUSE; BIOSYNTHESIS; COMPARATIVE STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE REARRANGEMENT; IMMUNOLOGY; MOLECULAR GENETICS; MOUSE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; B-LYMPHOCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; FEMALE; IMMUNODOMINANT EPITOPES; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES;

EID: 0030266699     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. Paige, C. J., and G. E. Wu. 1989. The B cell repertoire. FASEB J. 3:818.
2. Bona, C. A. 1992. Expression of V gene families during ontogeny and establishment of B cell repertoire. Int. Rev. Immunol. 8:83.
3. Nossal, G. J. V. 1992. The molecular and cellular basis of affinity maturation in the antibody response. Cel. 68:1.
4. Nossal, G. J. V. 1994. Differentiation of the secondary B lymphocyte repertoire: the germinal center reaction. Immunol. Rev. 137:173.
5. Jacob, J., K. Ramtin, and G. Kelsoe. 1991. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations. J. Exp. Med. 173:1165.
6. George, J., and L. Claflin. 1992. Selection of B cell clones and memory B cells. Semin. Immunol. 4:11.
7. Butcher, E. C., R. V. Rouse, R. L. Coffmann, C. N. Nottenberg, R. R. Hardy, and I. L. Weissman. 1982. Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation. J. Immunol. 129:2698.
8. Havran, W. L., D. L. DiGuisto, and J. Cambier. 1984. mIgM:mIgD ratios on B cells: mean mIgD exceeds mIgM by 10-fold on most splenic B cells. J. Immunol. 132:1712.
9. Jacob, J., J. Przylepa, C. Miller, and G. Kelsoe. 1993. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells. J. Exp. Med. 178: 1293.
10. +, B cells from antibody secreting and memory B cell pathways in the C57B1/6 immune response to NP. Eur. J. Immunol. 22: 3001.
11. Kuppers, R., M. Zhao, M. Hansmann, and K. Rajewsky. 1993. Tracing B cell development in human germinal centers by molecular analysis of single cells picked from histological sections. EMBO J. 12:4955.
12. McHeyzer-Williams, M. G., M. J. McLean, P. A. Lalor, and G. J. V. Nossal. 1993. Antigen-driven B cell differentiation in vivo. J. Exp. Med. 178:295.
13. Neuberger, M. S., and C. Milstein. 1995. Somatic hypermutation. Curr. Opin. Immunol. 7:248.
14. Liu., Y.-L., G. D. Johnson, J. Gordon, and I. C. M. MacLennan. 1992. Germinal centers in T-cell-dependent antibody responses. Immunol. Today 13:17.
15. Leanderson, T., E. Kallenberg, and D. Gray. 1992. Expansion, selection and maturation of antibody-specific B cells in germinal centers. Immunol. Rev. 126: 47.
16. Zeigner, M., G. Steinhauser, and C. Berek. 1994. Development of antibody in single germinal centers: selective expansion of high-affinity variants. Eur. J. Immunol. 24:2393.
17. Kelsoe, G. 1995. The germinal center reaction. Immunol. Today 16:324.
18. Berek, C., and C. Milstein. 1988. The dynamic nature of the antibody repertoire. Immunol. Rev. 105:5.
19. Makela, O., and M. Kaartinen. 1988. Genetic control of early antibody responses. Immunol. Rev. 105:85.
20. Rudikoff, S. 1988. Antibodies to β(1,6)-D-galactan: proteins, idiotypes and genes. Immunol. Rev. 105:97.
21. Stenzel-Poore, M. P., U. Bruderer, and M. B. Rittenberg. 1988. The adaptive potential of the memory response: clonal recruitment and recognition. Immunol. Rev. 105:113.
22. Dyson, J. H., and P. E. Wright. 1995. Antigenic peptides. FASEB J. 9:37.
23. Merrifield, R. B. 1986. Solid phase synthesis. Science 232:341.
24. Stewart, J. M., and J. D. Young. 1984. Solid Phase Peptide Synthesis, 2nd Ed. Pierce Chemical Co., Rockford, IL.
25. Atherton, E., and R. C. Sheppard. 1989. Solid Phase Peptide Synthesis: A Practical Approach. IRL Press, Oxford, U.K.
26. Geysen, H. M., S. J. Rodda, T. J. Mason, G. Tribbick, and P. G. Schoofs. 1987. Strategies for epitope analysis using peptide synthesis. J. Immunol. Methods 102: 259.
27. Coligon, J. E., A. M. Kruisbeck, D. M. Margolies, E. M. Shevach, and W. M. Stoker. 1991. Current Protocols in Immunology. John Wiley and Sons, New York, p. 25.
28. Neurath, A. R., and S. B. H. Kent. 1988. The pre-S region of hepadna virus envelope protein. Adv. Virus Res. 34:64.
29. Sinigaglia, F., M. Guttinger, J. Kilgus, D. M. Doran, H. Matile, H. Etlinger, A. Trzeciak, D. Gillessen, and J. R. L. Pink. 1988. A malaria T cell epitope recognized in association with most mouse and human MHC class II molecules. Nature 336:778.
30. Panina-Bordignon, P. A. Tan, A. Termijtelen, S. Demotz, G. P. Corradin, and A. Lanzavecchia. 1989. Universally immunogenic T cell epitopes: promiscuous binding to human class II and promiscuous recognition by T cells. Eur. J. Immunol. 19:2237.
31. Rao, K. V. S., and A. R. Nayak. 1990. Enhanced immunogenicity of a sequence derived from hepatitis B virus surface antigen in a composite peptide that includes the immunostimulatory region from human interleukin-1. Proc. Natl. Acad. Sci. USA 87:5519.
32. Kironde, F. A. S., K. V. S. Rao, S. Shah, A. Kumar, and N Sahoo. 1991. Towards the design of heterovalent anti-malaria vaccines: a hybrid immunogen capable of eliciting immune responses to epitopes of circumsporozoite antigen from two different species of the malaria parasite, Plasmodium. Immunology 74:323.
33. Dyson, J. H., and P. E. Wright. 1991. Defining solution conformations of small linear peptides. Annu. Rev. Biophys. Biophys. Chem. 20:519.
34. Vijayakrishnan, L., V. Kumar, J. N. Agrewala, G. C. Mishra, and K. V. S. Rao. 1994. Antigen-specific early primary humoral responses modulate immunodominance of B cell epitopes. J. Immunol. 153:1613.
35. Rossi, F., B. Guilbert, C. Tonnelli, T. Terynck, F. Fumoux, S. Avrameas, and D. Kazatchkine. 1990. Idiotypic interactions between normal human polyspecific IgG and natural IgM antibodies. Eur. J. Immunol. 20:2089.
36. Schwartz, R. S., and B. D. Stollar. 1994. Heavy-chain directed B cell maturation: continuous clonal selection beginning at the pre-B cell stage. Immunol. Today 15:27.
37. Melchers, F., A. Rolink, U. Grawunder, T. H. Winkler, H. Karasuyama, P. Ghia, and J. Anderson. 1995. Positive and negative selection events during B lymphopoiesis. Curr. Opin. Immunol. 7:214.
38. Ross, P. D., and S. Subramaniam. 1981. Thermodynamics of protein association reactions: forces contributing to stability. Biochemistry 20:3096.
39. Ito, W., Y. Iba, and Y. Kurosawa. 1993. Effects of substitutions of closely related amino acids at the contact surface in an antigen-antibody complex on thermodynamic parameters. J. Biol. Chem. 268:16639.
40. Braden, B. C., and R. J. Poljak. 1995. Structural features of the reactions between antibodies and protein antigens. FASEB J. 9:9.
41. Foote, J., and C. Milstein. 1991. Kinetic maturation of an immune response. Nature 352:530.
42. Vora, K. A., and T. Manser. 1995. Altering the antibody repertoire via transgene homologous recombination: evidence for global and clone-autonomous regulation of antigen-driven B cell differentiation. J. Exp. Med. 181:271.
43. Mamula, M. J., and C. A. Janeway. 1993. Do B cells drive the diversification of immune responses? Immunol. Today 14:151.