αv integrin expression is a novel marker of poor prognosis in advanced-stage ovarian carcinoma

Clinical Cancer Research

Volumn 7, Issue 12, 2001, Pages 4073-4079

  Goldberg, Iris ^a   Kopolovic, Juri ^a   Gotlieb, Walter H ^a   Ben Baruch, Gilad ^a   Davidson, Ben ^b   Berner, Aasmund ^b   Nesland, Jahn M ^b   Bryne, Magne ^b   Reich, Reuven ^c  

^a SHEBA MEDICAL CENTER   (Israel)

^b UNIVERSITY OF OSLO   (Norway)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CD29 ANTIGEN; CD51 ANTIGEN; LEUKOCYTE ANTIGEN; MESSENGER RNA; BETA1 INTEGRIN; INTEGRIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER STAGING; CLASSIFICATION; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HUMAN; MORTALITY; OVARY TUMOR; PATHOLOGY; PROGNOSIS; STROMA CELL; SURVIVAL; SURVIVAL RATE; TIME; ADVANCED CANCER; CLINICAL ARTICLE; CORRELATION FUNCTION; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE MARKER; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; METASTASIS; OVARY CARCINOMA; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ANALYSIS; SURVIVAL TIME;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD; ANTIGENS, CD29; DISEASE-FREE SURVIVAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMAN; INTEGRIN ALPHAV; MIDDLE AGE; NEOPLASM STAGING; OVARIAN NEOPLASMS; PROGNOSIS; RNA, MESSENGER; STROMAL CELLS; SURVIVAL RATE; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 0035542949     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Integrins
2. Signaling by integrin receptors
3. The role of integrins in tumorigenesis and metastasis
4. Role of integrins and other cell adhesion molecules in tumor progression and metastasis
5. Recent insights into the role of integrins in cancer metastasis
6. Integrins and cancer
7. Biology of tumor cell invasion: Interplay of cell adhesion and matrix degradation
8. Global cancer statistics
9. Prospective on ovarian cancer: Why prevent?
10. Evidence for preferential adhesion of ovarian epithelial carcinoma cells to type I collagen mediated by the α2β1 integrin
11. αvβ3 and vitronectin expression by normal ovarian surface epithelial cells: Role in cell adhesion and cell proliferation
12. Expression and localization of αv integrins and their ligand vitronectin in normal ovarian epithelium and in ovarian carcinoma
13. Expression and function of β1 and αvβ3 integrins in ovarian cancer
14. Localization of the alpha 3 beta 1 integrin in some common epithelial tumors of the ovary and in normal equivalents
15. Expression of αvβ3 integrin is less frequent in ovarian epithelial tumors of low malignant potential in contrast to ovarian carcinomas
16. High levels of MMP-2, MMP-9, MT1-MMP and TIMP-2 mRNA correlate with poor survival in ovarian carcinoma
17. Expression of carbohydrate antigens in advanced-stage ovarian carcinomas and their metastases- a clinicopathologic study
18. E-cadherin complex protein expression and survival in ovarian carcinoma
19. Ets-1 mRNA expression is a novel marker of poor survival in ovarian carcinoma
20. Caveolin-1 expression in advanced-stage ovarian carcinoma-clinicopathologic study
21. Expression of angiogenesis-related genes in ovarian carcinoma. A clinicopathologic study
22. Surface epithelialstromal tumors
23. MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma: A clinicopathologic study using immunohistochemistry and mRNA in situ hybridization
24. Extracellular matrix expression in metastasizing and nonmetastasizing adenocarcinomas of the lung
25. Loss of α-v integrin expression and recurrence in node-negative lung carcinoma
26. Vascular integrin α(v)β3: A new prognostic indicator in breast cancer