메뉴 건너뛰기




Volumn 73, Issue 3, 1999, Pages 372-382

MMP-2 and TIMP-2 expression correlates with poor prognosis in cervical carcinoma - A clinicopathologic study using immunohistochemistry and mRNA in situ hybridization

Author keywords

CIN; Immunohistochemistry; MMP 2; MRNA in situ hybridization; MT1 MMP; Patient survival; Squamous cell carcinoma; TIMP 2; Uterine cervix

Indexed keywords

GELATINASE A; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

EID: 0033019235     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.1999.5381     Document Type: Article
Times cited : (114)

References (50)
  • 1
    • 0021079540 scopus 로고
    • Tumor invasion and the extracellular matrix
    • Liotta L A, Rao C N, Barsky S H. Tumor invasion and the extracellular matrix. Lab Invest. 49:1983;636-649.
    • (1983) Lab Invest , vol.49 , pp. 636-649
    • Liotta, L.A.1    Rao, C.N.2    Barsky, S.H.3
  • 2
    • 0028675819 scopus 로고
    • Tumor and stromal expression of matrix metalloproteinases and their role in tumor progression
    • Crawford, H, C, Matrisian, L, N: Tumor and stromal expression of matrix metalloproteinases and their role in tumor progression. Invasion Metastasis14:234-245, 1994-1995.
    • (1994) Invasion Metastasis , vol.14 , pp. 234-245
    • Crawford, H.C.1    Matrisian, L.N.2
  • 4
    • 0026896029 scopus 로고
    • The matrix-degrading metalloproteinases
    • Matrisian L M. The matrix-degrading metalloproteinases. Bioessays. 14:1992;455-463.
    • (1992) Bioessays , vol.14 , pp. 455-463
    • Matrisian, L.M.1
  • 5
    • 0026425631 scopus 로고
    • Tumor invasion and metastasis: An imbalance of positive and negative regulation
    • Liotta L A, Stetler-Stevenson W G. Tumor invasion and metastasis: an imbalance of positive and negative regulation. Cancer Res. 51:1991;5054-5059s.
    • (1991) Cancer Res , vol.51
    • Liotta, L.A.1    Stetler-Stevenson, W.G.2
  • 7
    • 0028292599 scopus 로고
    • Tumor cell invasion, matrix metalloproteinases, and the dogma
    • Furcht L T, Skubitz A PN, Fields G B. Tumor cell invasion, matrix metalloproteinases, and the dogma. Lab Invest. 70:1994;781-783.
    • (1994) Lab Invest , vol.70 , pp. 781-783
    • Furcht, L.T.1    Skubitz, A.P.2    Fields, G.B.3
  • 8
    • 0030136756 scopus 로고    scopus 로고
    • Dynamics of matrix turnover during pathologic remodeling of the extracellular matrix
    • Stetler-Stevenson W G. Dynamics of matrix turnover during pathologic remodeling of the extracellular matrix. Am J Pathol. 148:1996;1345-1350.
    • (1996) Am J Pathol , vol.148 , pp. 1345-1350
    • Stetler-Stevenson, W.G.1
  • 9
    • 0031297456 scopus 로고    scopus 로고
    • Control of matrix metalloproteinase activity in cancer
    • Jones J L, Walker R A. Control of matrix metalloproteinase activity in cancer. J Pathol. 183:1997;377-379.
    • (1997) J Pathol , vol.183 , pp. 377-379
    • Jones, J.L.1    Walker, R.A.2
  • 10
    • 0028347399 scopus 로고
    • Immunohistochemical localization of matrix metalloproteinase 2 and its specific inhibitor TIMP-2 in neoplastic tissues with monoclonal antibodies
    • Hoyhtya M, Fridman R, Komarek D, Porter J K, Stetler- Stevenson W G, Liotta L A, Liang C M. Immunohistochemical localization of matrix metalloproteinase 2 and its specific inhibitor TIMP-2 in neoplastic tissues with monoclonal antibodies. Int J Cancer. 56:1994;500-505.
    • (1994) Int J Cancer , vol.56 , pp. 500-505
    • Hoyhtya, M.1    Fridman, R.2    Komarek, D.3    Porter, J.K.4    Stetler- Stevenson, W.G.5    Liotta, L.A.6    Liang, C.M.7
  • 12
    • 0025262040 scopus 로고
    • Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue
    • Monteagudo C, Merino M J, San J J, Liotta L A, Stetler-Stevenson W G. Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue. Am J Pathol. 136:1990;585-592.
    • (1990) Am J Pathol , vol.136 , pp. 585-592
    • Monteagudo, C.1    Merino, M.J.2    San, J.J.3    Liotta, L.A.4    Stetler-Stevenson, W.G.5
  • 13
    • 0028178968 scopus 로고
    • Expression and activity of MMPs and their regulators in ovarian cancer
    • Naylor M S, Stamp G WH, Davies B, Balkwill F R. Expression and activity of MMPs and their regulators in ovarian cancer. Int J Cancer. 58:1994;50-56.
    • (1994) Int J Cancer , vol.58 , pp. 50-56
    • Naylor, M.S.1    Stamp, G.W.2    Davies, B.3    Balkwill, F.R.4
  • 15
    • 0027497835 scopus 로고
    • Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer
    • Pyke C, Ralfkiaer E, Tryggvason K, Dano K. Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer. Am J Pathol. 142:1993;359-365.
    • (1993) Am J Pathol , vol.142 , pp. 359-365
    • Pyke, C.1    Ralfkiaer, E.2    Tryggvason, K.3    Dano, K.4
  • 16
    • 0028024812 scopus 로고
    • Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy
    • Polette M, Gilbert N, Stas I, Nawrocki B, Noel A, Remacle A, Stetler-Stevenson W M, Birembaut P, Foidart M. Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy. Virchows Arch. 424:1994;641-645.
    • (1994) Virchows Arch , vol.424 , pp. 641-645
    • Polette, M.1    Gilbert, N.2    Stas, I.3    Nawrocki, B.4    Noel, A.5    Remacle, A.6    Stetler-Stevenson, W.M.7    Birembaut, P.8    Foidart, M.9
  • 19
    • 0028854873 scopus 로고
    • Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma
    • Nuovo G J, MacConnel P B, Simsir A, Valea F, French D L. Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma. Cancer Res. 55:1995;267-275.
    • (1995) Cancer Res , vol.55 , pp. 267-275
    • Nuovo, G.J.1    MacConnel, P.B.2    Simsir, A.3    Valea, F.4    French, D.L.5
  • 20
    • 0030020982 scopus 로고    scopus 로고
    • The 72-kDa metalloproteinase immunostaining in cervical carcinoma: Relationship with lymph nodal involvement
    • Garzetti G G, Ciavattini A, Lucarini G, Goteri G, Romanini C, Biagini G. The 72-kDa metalloproteinase immunostaining in cervical carcinoma: relationship with lymph nodal involvement. Gynecol Oncol. 60:1996;271-276.
    • (1996) Gynecol Oncol , vol.60 , pp. 271-276
    • Garzetti, G.G.1    Ciavattini, A.2    Lucarini, G.3    Goteri, G.4    Romanini, C.5    Biagini, G.6
  • 21
    • 0029119363 scopus 로고
    • Analysis of expression of matrix metalloproteinase-2 and -9 in squamous cell carcinoma by in situ hybridization
    • Miyajima Y, Nakano R, Morimatsu M. Analysis of expression of matrix metalloproteinase-2 and -9 in squamous cell carcinoma by in situ hybridization. Ann Otol Rhinol Laryngol. 104:1995;674-684.
    • (1995) Ann Otol Rhinol Laryngol , vol.104 , pp. 674-684
    • Miyajima, Y.1    Nakano, R.2    Morimatsu, M.3
  • 22
    • 0026464485 scopus 로고
    • Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study
    • Shima I, Sagaguri Y, Kusukawa J, Yamana H, Fujita H, Kakegawa T, Morimatsu M. Production of matrix metalloproteinase-2 and metalloproteinase-3 related to malignant behavior of esophageal carcinoma. A clinicopathologic study. Cancer. 70:1992;2747-2753.
    • (1992) Cancer , vol.70 , pp. 2747-2753
    • Shima, I.1    Sagaguri, Y.2    Kusukawa, J.3    Yamana, H.4    Fujita, H.5    Kakegawa, T.6    Morimatsu, M.7
  • 23
    • 0028838487 scopus 로고
    • Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT1-MMP) and with lymph node metastasis
    • Tokuraku M, Sato H, Murakami S, Okada Y, Watanabe Y, Seiki M. Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT1-MMP) and with lymph node metastasis. Int J Cancer. 64:1995;355-359.
    • (1995) Int J Cancer , vol.64 , pp. 355-359
    • Tokuraku, M.1    Sato, H.2    Murakami, S.3    Okada, Y.4    Watanabe, Y.5    Seiki, M.6
  • 24
    • 0027469921 scopus 로고
    • Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma
    • Brown P D, Bloxidge R E, Stuart N S, Gatter K C, Carmichael J. Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma. J Natl Cancer Inst. 85:1995;574-578.
    • (1995) J Natl Cancer Inst , vol.85 , pp. 574-578
    • Brown, P.D.1    Bloxidge, R.E.2    Stuart, N.S.3    Gatter, K.C.4    Carmichael, J.5
  • 25
    • 0029831503 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 (72 kD type IV collagenase) expression occurs in the early stage of human melanocytic tumour progression and may have prognostic value
    • Vaisanen A, Tuominen H, Kallioinen M, Turpeenniemi-Hujanen T. Matrix metalloproteinase-2 (72 kD type IV collagenase) expression occurs in the early stage of human melanocytic tumour progression and may have prognostic value. J Pathol. 180:1996;283-289.
    • (1996) J Pathol , vol.180 , pp. 283-289
    • Vaisanen, A.1    Tuominen, H.2    Kallioinen, M.3    Turpeenniemi-Hujanen, T.4
  • 26
    • 0025033983 scopus 로고
    • Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor clines and human tumor tissues
    • Stetler-Stevenson W G, Brown P D, Onisto M, Levy A T, Liotta L A. Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor clines and human tumor tissues. J Biol Chem. 265:1990;13933-13938.
    • (1990) J Biol Chem , vol.265 , pp. 13933-13938
    • Stetler-Stevenson, W.G.1    Brown, P.D.2    Onisto, M.3    Levy, A.T.4    Liotta, L.A.5
  • 27
    • 0025944065 scopus 로고
    • The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity
    • Murphy G, Houbrechts A, Cockett M I, Williamson R A, O'Shea M, Docherty A JP. The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity. Biochemistry. 30:1991;8097-8102.
    • (1991) Biochemistry , vol.30 , pp. 8097-8102
    • Murphy, G.1    Houbrechts, A.2    Cockett, M.I.3    Williamson, R.A.4    O'Shea, M.5    Docherty, A.J.6
  • 28
    • 0006506596 scopus 로고
    • Human 72 kDa type IV collagenase forms a complex with a tissue inhibitor of metallproteinase designated TIMP-2
    • Goldberg G I, Marmer B L, Grant G A, Eisen A Z, Wilhelm S, He C. Human 72 kDa type IV collagenase forms a complex with a tissue inhibitor of metallproteinase designated TIMP-2. Proc Natl Acad Sci USA. 86:1989;8207-8211.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 8207-8211
    • Goldberg, G.I.1    Marmer, B.L.2    Grant, G.A.3    Eisen, A.Z.4    Wilhelm, S.5    He, C.6
  • 29
    • 0026903364 scopus 로고
    • The matrix metalloproteinases and their inhibitors
    • Murphy G, Docherty A JP. The matrix metalloproteinases and their inhibitors. Am J Respir Cell Mol Biol. 7:1992;120-125.
    • (1992) Am J Respir Cell Mol Biol , vol.7 , pp. 120-125
    • Murphy, G.1    Docherty, A.J.2
  • 30
    • 0028907318 scopus 로고
    • Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease
    • Strongin A Y, Collier I, Bannikov G, Marmer B L, Grant G A, Goldberg G I. Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease. J Biol Chem. 270:1995;5331-5338.
    • (1995) J Biol Chem , vol.270 , pp. 5331-5338
    • Strongin, A.Y.1    Collier, I.2    Bannikov, G.3    Marmer, B.L.4    Grant, G.A.5    Goldberg, G.I.6
  • 31
    • 0027172634 scopus 로고
    • Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2
    • Strongin A Y, Marmer B L, Grant G A, Goldberg G I. Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TIMP-2. J Biol Chem. 268:1993;14033-14039.
    • (1993) J Biol Chem , vol.268 , pp. 14033-14039
    • Strongin, A.Y.1    Marmer, B.L.2    Grant, G.A.3    Goldberg, G.I.4
  • 32
    • 0025831950 scopus 로고
    • Tissue inhibitor of metalloproteinases-2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes
    • Ward R V, Atkinson S J, Slocombe P M, Docherty A J, Reynolds J J, Murphy G. Tissue inhibitor of metalloproteinases-2 inhibits the activation of 72 kDa progelatinase by fibroblast membranes. Biochym Biophys Acta. 1079:1991;242-246.
    • (1991) Biochym Biophys Acta , vol.1079 , pp. 242-246
    • Ward, R.V.1    Atkinson, S.J.2    Slocombe, P.M.3    Docherty, A.J.4    Reynolds, J.J.5    Murphy, G.6
  • 33
    • 0028935326 scopus 로고
    • Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas
    • Okada A, Bellocq J P, Rouyer N, Chenard M P, Rio M C, Chambon P, Basset P. Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. Proc Natl Acad Sci USA. 92:1995;2730-2734.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2730-2734
    • Okada, A.1    Bellocq, J.P.2    Rouyer, N.3    Chenard, M.P.4    Rio, M.C.5    Chambon, P.6    Basset, P.7
  • 35
    • 0030030957 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression and synthetic matrix metalloproteinase-2 inhibitor binding in ovarian carcinomas and tumor cell lines
    • Afzal S, Lalani E N, Foulkes W D, Boyce B, Tickle S, Cardillo M R, Baker T, Pignatelli M, Stamp G WH. Matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression and synthetic matrix metalloproteinase-2 inhibitor binding in ovarian carcinomas and tumor cell lines. Lab Invest. 74:1996;406-421.
    • (1996) Lab Invest , vol.74 , pp. 406-421
    • Afzal, S.1    Lalani, E.N.2    Foulkes, W.D.3    Boyce, B.4    Tickle, S.5    Cardillo, M.R.6    Baker, T.7    Pignatelli, M.8    Stamp, G.W.9
  • 36
    • 0030951910 scopus 로고    scopus 로고
    • Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas
    • Ueno H, Nakamura H, Inoue M, Imai K, Noguchi M, Sato H, Seiki M, Okada Y. Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Res. 57:1997;2055-2060.
    • (1997) Cancer Res , vol.57 , pp. 2055-2060
    • Ueno, H.1    Nakamura, H.2    Inoue, M.3    Imai, K.4    Noguchi, M.5    Sato, H.6    Seiki, M.7    Okada, Y.8
  • 37
    • 0030922614 scopus 로고    scopus 로고
    • Implication of collagen type I-induced membrane type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma
    • Gilles C, Polette M, Seiki M, Birembaut P, Thompson E W. Implication of collagen type I-induced membrane type 1-matrix metalloproteinase expression and matrix metalloproteinase-2 activation in the metastatic progression of breast carcinoma. Lab Invest. 76:1997;651-660.
    • (1997) Lab Invest , vol.76 , pp. 651-660
    • Gilles, C.1    Polette, M.2    Seiki, M.3    Birembaut, P.4    Thompson, E.W.5
  • 39
    • 0028148301 scopus 로고
    • Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence
    • Visscher D W, Hoyhtya M, Ottosen S K, Liang C M, Sarkar F H, Crissman J D, Fridman R. Enhanced expression of tissue inhibitor of metalloproteinase-2 (TIMP-2) in the stroma of breast carcinomas correlates with tumor recurrence. Int J Cancer. 59:1994;339-344.
    • (1994) Int J Cancer , vol.59 , pp. 339-344
    • Visscher, D.W.1    Hoyhtya, M.2    Ottosen, S.K.3    Liang, C.M.4    Sarkar, F.H.5    Crissman, J.D.6    Fridman, R.7
  • 40
    • 0013639560 scopus 로고    scopus 로고
    • FIGO Staging for Carcinoma of the Cervix Uteri
    • J. Rosai. St. Louis: Mosby
    • Rosai J. FIGO Staging for Carcinoma of the Cervix Uteri. Rosai J. Ackerman's Surgical Pathology. 1996;1367 Mosby, St. Louis.
    • (1996) Ackerman's Surgical Pathology , pp. 1367
    • Rosai, J.1
  • 41
    • 0026321330 scopus 로고
    • Automated molecular pathology: One-hour in-situ DNA hybridization
    • Parks C S, Brigati D J, Manahan L J. Automated molecular pathology: one-hour in-situ DNA hybridization. J Histotechnol. 14:1991;219-229.
    • (1991) J Histotechnol , vol.14 , pp. 219-229
    • Parks, C.S.1    Brigati, D.J.2    Manahan, L.J.3
  • 42
    • 0026709418 scopus 로고
    • Complete one-hour immunocytochemistry based on capillary action
    • Reed J A, Manahan L J, Parks C S, Brigati D J. Complete one-hour immunocytochemistry based on capillary action. Biotechniques. 13:1992;434-443.
    • (1992) Biotechniques , vol.13 , pp. 434-443
    • Reed, J.A.1    Manahan, L.J.2    Parks, C.S.3    Brigati, D.J.4
  • 43
    • 0030969422 scopus 로고    scopus 로고
    • Correlation of metastasis-related gene expression with metastatic potential in human prostate carcinoma cells implanted in nude mice using an in situ messenger RNA hybridization technique
    • Greene G F, Kitadai Y, Pettaway C A, von Eschenbach A C, Bucana C D, Fidler I J. Correlation of metastasis-related gene expression with metastatic potential in human prostate carcinoma cells implanted in nude mice using an in situ messenger RNA hybridization technique. Am J Pathol. 150:1997;1571-1582.
    • (1997) Am J Pathol , vol.150 , pp. 1571-1582
    • Greene, G.F.1    Kitadai, Y.2    Pettaway, C.A.3    Von Eschenbach, A.C.4    Bucana, C.D.5    Fidler, I.J.6
  • 44
    • 0021740649 scopus 로고
    • A comparison of two immunoperoxidase staining methods based on the avidin-biotin interaction
    • Giorno R. A comparison of two immunoperoxidase staining methods based on the avidin-biotin interaction. Diagn Immunol. 2:1984;161-166.
    • (1984) Diagn Immunol , vol.2 , pp. 161-166
    • Giorno, R.1
  • 45
    • 0018307692 scopus 로고
    • The use of avidin-biotin interaction in immunoenzymatic techniques
    • Guesdon J L, Ternynck T, Avrameas S. The use of avidin-biotin interaction in immunoenzymatic techniques. J Histochem Cytochem. 27:1979;1131-1139.
    • (1979) J Histochem Cytochem , vol.27 , pp. 1131-1139
    • Guesdon, J.L.1    Ternynck, T.2    Avrameas, S.3
  • 46
    • 0032981670 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinase-9 in squamous cell carcinoma of the uterine cervix-clinicopathologic study using immunohistochemistry and mRNA in situ hybridization
    • Davidson B, Goldberg I, Kopolovic J, Lerner-Geva L, Gotlieb W H, Weis B, Ben-Baruch G, Reich R. Expression of matrix metalloproteinase-9 in squamous cell carcinoma of the uterine cervix-clinicopathologic study using immunohistochemistry and mRNA in situ hybridization. Gynecol Oncol. 72:1999;380-386.
    • (1999) Gynecol Oncol , vol.72 , pp. 380-386
    • Davidson, B.1    Goldberg, I.2    Kopolovic, J.3    Lerner-Geva, L.4    Gotlieb, W.H.5    Weis, B.6    Ben-Baruch, G.7    Reich, R.8
  • 48
    • 0029806982 scopus 로고    scopus 로고
    • Dual over-expression pattern of membrane-type metalloproteinase-1 in cancer and stromal cells in human gastrointestinal carcinoma revealed by in situ hybridization and immunoelectron microscopy
    • Ohtani H, Motohashi H, Sato H, Seiki M, Nagura H. Dual over-expression pattern of membrane-type metalloproteinase-1 in cancer and stromal cells in human gastrointestinal carcinoma revealed by in situ hybridization and immunoelectron microscopy. Int J Cancer. 68:1996;565-570.
    • (1996) Int J Cancer , vol.68 , pp. 565-570
    • Ohtani, H.1    Motohashi, H.2    Sato, H.3    Seiki, M.4    Nagura, H.5
  • 49
    • 0031022581 scopus 로고    scopus 로고
    • Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma
    • Yoshizaki T, Sato H, Maruyama Y, Murono S, Furukawa M, Park C, Seiki M. Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma. Cancer. 79:1997;139-144.
    • (1997) Cancer , vol.79 , pp. 139-144
    • Yoshizaki, T.1    Sato, H.2    Maruyama, Y.3    Murono, S.4    Furukawa, M.5    Park, C.6    Seiki, M.7
  • 50
    • 0029103339 scopus 로고
    • Expression of membrane-type matrix metalloproteinase in human gastric carcinomas
    • Nomura H, Sato H, Seiki M, Mai M, Okada Y. Expression of membrane-type matrix metalloproteinase in human gastric carcinomas. Cancer Res. 55:1995;3263-3266.
    • (1995) Cancer Res , vol.55 , pp. 3263-3266
    • Nomura, H.1    Sato, H.2    Seiki, M.3    Mai, M.4    Okada, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.