Antagonistic effects of phorbol esters on insulin regulation of insulin-like growth factor-binding protein-1 (IGFBP-1) but not glucose-6-phosphatase gene expression

Biochemical Journal

Volumn 359, Issue 3, 2001, Pages 611-619

  Patel, S ^a   Lochhead, P A ^a   Rena, G ^a   Sutherland, C ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Forkhead; MAP kinase; PKB; Transcription

Indexed keywords

ESTERS; GENES; GROWTH KINETICS; INSULIN; PROTEINS;

PHOSPHORYLATION;

BIOCHEMISTRY;

2 (2 CHLORO 4 IODOANILINO) N CYCLOPROPYLMETHOXY 3,4 DIFLUOROBENZAMIDE; GLUCOSE 6 PHOSPHATASE; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL ESTER; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN BINDING PROTEIN 1; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE SEQUENCE; GENETIC TRANSCRIPTION; INSULIN RESISTANCE; INSULIN RESPONSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; BENZAMIDES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CULTURE MEDIA, SERUM-FREE; CYCLIC AMP; DEXAMETHASONE; DNA-BINDING PROTEINS; ENZYME INHIBITORS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; GLUCOSE-6-PHOSPHATASE; GLYCOGEN SYNTHASE KINASE 3; INSULIN; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE TISSUE PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RIBOSOMAL PROTEIN S6 KINASES; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0035504564     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3590611     Document Type: Article

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