The impact of different flavonoid classes on colonic CI- secretion in rats

Biochemical Pharmacology

Volumn 62, Issue 8, 2001, Pages 1145-1151

  Cermak, Rainer ^a   Vujicic, Zoran ^a   Scharrer, Erwin ^a   Wolfram, Siegfried ^b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF KIEL   (Germany)

Author keywords

CI ; Colon; Flavonoids; Flavonols; Plant polyphenols; Secretion

Indexed keywords

CARBON; CATECHIN; CYANIDIN CHLORIDE; ERIODICTYOL; FLAVAN DERIVATIVE; FLAVANOID; FLAVANOL DERIVATIVE; FLAVANONE DERIVATIVE; FUNCTIONAL GROUP; GALANGIN; GENISTEIN; GLYCOSIDE; HYDROXYL GROUP; ISOQUERCITRIN; ISORHAMNETIN; KAEMPFEROL; LUTEOLIN; METHYL GROUP; MYRICETIN; OXYGEN DERIVATIVE; QUERCETIN DERIVATIVE; RUTOSIDE; SPIRAEOSIDE; TAMARIXETIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CHEMICAL BOND; CHEMICAL REACTION; COLON SECRETION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; MALE; NONHUMAN; PLANT; PRIORITY JOURNAL; RAT; SHORT CIRCUIT CURRENT; STRUCTURE ACTIVITY RELATION;

ANIMALS; CHLORIDES; COLON; FLAVANONES; FLAVONOIDS; ISOFLAVONES; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0035501482     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00758-4     Document Type: Article

References (26)

1. Review of the biology of quercetin and related bioflavonoids
2. Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine
3. Dietary flavonoids: Intake, health effects and bioavailability
4. Plant polyphenols in cancer and heart disease: Implications as nutritional antioxidants
5. The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
6. The relative antioxidant activities of plant-derived polyphenolic flavonoids
7. Flavonoids as antioxidants: Determination of radical scavenging efficiencies
8. Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance
9. Dietary flavonol quercetin induces chloride secretion in rat colon
10. - secretion in rat distal colon by genistein, a protein tyrosine kinase inhibitor
11. - secretion in the murine trachea and colon
12. Effect of genistein on native epithelial tissue from normal individuals and CF patients and on ion channels expressed in Xenopus oocytes
13. 2+-calmodulin
14. 14C]quercetin in the ACI rat
15. Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties
16. Dietary quercetin is recovered in rat plasma as conjugated derivates of isorhamnetin and quercetin
17. Bioavailability and metabolism of the flavonol quercetin in the pig
18. Part of quercetin absorbed in the small intestine is conjugated and further secreted in the intestinal lumen
19. Plasma kinetics and urinary excretion of the flavanones naringenin and hesperetin in humans after ingestion of orange juice and grapefruit juice
20. Intestinal absorption of luteolin and luteolin 7-O-β-glucoside in rats and humans
21. The small intestine can both absorb and glucuronidate luminal flavonoids
22. β-Glucosidase activity in the rat small intestine toward quercetin monoglucosides
23. Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver β-glucosidase activity
24. Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase
25. Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissues
26. Epicatechin and catechin are O-methylated and glucuronidated in the small intestine