Regulation of Ins(1,4,5)P3 receptor isoforms by endogenous modulators

Trends in Pharmacological Sciences

Volumn 22, Issue 11, 2001, Pages 580-586

  Thrower, Edwin C ^a   Hagar, Robert E ^a,b   Ehrlich, Barbara E ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CALMODULIN; CALMODULIN INHIBITOR; INOSITOL TRISPHOSPHATE; NUCLEOTIDE; RECEPTOR;

AMINO TERMINAL SEQUENCE; CALCIUM SIGNALING; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CYTOSOL; DEPHOSPHORYLATION; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; RECEPTOR BINDING; REVIEW; SEQUENCE HOMOLOGY;

ANIMALS; CALCIUM CHANNELS; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; PHOSPHORYLATION; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

EID: 0035499903     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(00)01809-5     Document Type: Review

References (59)

1. Expression of inositol trisphosphate receptors
2. Conservation of localization patterns of IP(3) receptor type 1 in cerebellar Purkinje cells across vertebrate species
3. Mapping of the atp-binding sites on inositol 1,4,5-trisphosphate receptor type 1 and type 3 homotetramers by controlled proteolysis and photoaffinity labeling
4. Structural and functional characterization of inositol 1,4,5-trisphosphate receptor channel from mouse cerebellum
5. 2+-binding domains in the type 1 inositol 1,4,5-trisphosphate receptor
6. Molecular properties of inositol 1,4,5-trisphosphate receptors
7. Inositol 1,4,5-trisphosphate receptor is phosphorylated by cyclic AMP-dependent protein kinase at serines 1755 and 1589
8. Calmodulin mediates calcium-dependent inactivation of the cerebellar type 1 inositol 1,4,5-trisphosphate receptor
9. FKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domain
10. 2+ wave trigger zone of the pancreatic acinar cells
11. 2+ signaling patterns in nonpigmented ciliary epithelia
12. Differential cellular expression of isoforms of inositol 1,4,5-triphosphate receptors in neurons and glia in brain
13. Isoform-specific function of single inositol 1,4,5-trisphosphate receptor channels
14. Type III InsP3 receptors stay open in the presence of increased calcium
15. 2+ activation
16. 2+ entry, and proliferation of A7r5 vascular smooth muscle cells
17. ATP modulates the function of inositol 1,4,5-trisphosphate-gated channels at two sites
18. Striated scallop muscle relaxation: Fast force transients produced by photolysis of Diazo-2
19. Calcium flux mediated by purified inositol 1,4,5-trisphosphate receptor in reconstituted lipid vesicles is allosterically regulated by adenine nucleotides
20. Effects of adenine nucleotides on inositol 1,4,5-trisphosphate-induced calcium release in vascular smooth muscle cells
21. Regulation of the type III InsP(3) receptor by InsP(3) and ATP
22. 2+ release from pituitary microsomal fractions
23. Differential modulation of inositol 1,4,5-trisphosphate receptor type 1 and type 3 by ATP
24. 3- and calcium-gated channels from endoplasmic reticulum of cerebellum
25. 3 receptor channels
26. 2+ channels of sarcoplasmic reticulum from frog skeletal muscle
27. 3-stimulated Ca mobilization in hepatocytes
28. 2+ release
29. 2+ liberation from intracellular stores
30. 2+ spiking in single smooth muscle cells
31. 2+ release from cerebellar microsomes
32. 2+ dependence of inositol 1,4,5-trisphosphate-induced Ca release in smooth muscle cells of the guinea pig Taenia caeci
33. 2+] on the cytosolic face of the inositol (1,4,5)-trisphosphate receptor at the single channel level
34. Characterization of a membrane protein from brain mediating the inhibition of inositol 1,4,5-trisphosphate receptor binding by calcium
35. 2+/calmodulin
36. Single-channel function of recombinant type 2 inositol 1,4,5-trisphosphate receptor
37. Multiple mechanisms of regulation of the inositol 1,4,5-trisphosphate receptor by calcium
38. Single-channel properties in endoplasmic reticulum membrane of recombinant type 3 inositol trisphosphate receptor
39. Functional properties of the type-3 InsP3 receptor in 16HBE14o-bronchial mucosal cells
40. Calmodulin-binding proteins in a cloned rat insulinoma cell line
41. The calmodulin-binding domain in the mouse type 1 inositol 1,4,5-trisphosphate receptor
42. Direct association of ligand-binding and pore domains in homo- and heterotetrameric inositol 1,4,5-trisphosphate receptors
43. 3 receptor-dependent calcium signaling
44. 2+ inhibition
45. Isolation, characterization and localization of the inositol 1,4,5-trisphosphate receptor protein in Xenopus laevis oocytes
46. The physiologic concentration of inositol 1,4,5-trisphosphate in the oocytes of Xenopus laevis
47. Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites
48. A new class of synaptic response involving calcium release in dendritic spines
49. Progressive disruption of acinar cell calcium signaling is an early feature of cerulein-induced pancreatitis in mice
50. Calcium signalling: How do IP3 receptors work?
51. Agonist-dependent phosphorylation of the inositol 1,4,5-trisphosphate receptor. A possible mechanism for agonist-specific calcium oscillations in pancreatic acinar cells
52. 2+ signals
53. Inositol trisphosphate receptor - Phosphorylation by protein kinase-C and calcium calmodulin-dependent protein kinases in reconstituted lipid vesicles
54. Phosphorylation of inositol 1,4,5-trisphosphate receptors by cAMP-dependent protein kinase. Type I, II, and III receptors are differentially susceptible to phosphorylation and are phosphorylated in intact cells
55. 2+ flux
56. Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor
57. Functional properties of recombinant type I and type III inositol 1,4,5-trisphosphate receptor isoforms expressed in COS-7 cells
58. Regulation of the inositol 1,4,5-trisphosphate receptor by tyrosine phosphorylation
59. The inositol 1,4,5-trisphosphate (InsP3) receptor