Polarity, protrusion-retraction dynamics and their interplay during keratinocyte cell migration

Experimental Cell Research

Volumn 270, Issue 2, 2001, Pages 129-137

  Libotte, Thorsten ^a   Kaiser, Hans Wilhelm ^b   Alt, Wolfgang ^a   Bretschneider, Till ^a  

^a UNIVERSITY OF BONN   (Germany)

^b Department of Dermatology ^*  (Germany)

Author keywords

Cell migration; Cell substrate adhesion; Fibronectin; Keratinocytes; Polarity; RGD; Ruffling

Indexed keywords

FIBRONECTIN;

ACCELERATION; ARTICLE; CELL ACTIVITY; CELL ADHESION; CELL KINETICS; CELL MIGRATION; CELL MOTILITY; CELL POLARITY; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; KERATINOCYTE; NEWBORN; PRIORITY JOURNAL;

EID: 0035498839     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2001.5339     Document Type: Article

References (55)

1. Epidermal differentiation: The bare essentials
2. Ultrastructure of the epidermis
3. Cell biology of wound healing
4. Role of integrins in cell adhesion and polarity in normal keratinocytes and human skin pathologies
5. 1 integrin loss from the cell surface
6. Fibronectin fibrillogenesis: A paradigm for extracellular matrix assembly
7. Mechanism of human keratinocyte migration on fibronectin: Unique roles of RGD site and integrins
8. Adhesive recognition sequences
9. Different integrins mediate cell spreading, haptotaxis and lateral migration of HaCaT keratinocytes of fibronectin
10. Activation of human keratinocyte migration on type I collagen and fibronectin
11. Dualistic nature of adhesive protein function: Fibronectin and its biologically active peptide fragments can autoinhibit fibronectin function
12. Analysis of fibronectin receptor function with monoclonal antibodies: Roles in cell adhesion; migration, matrix assembly and cytoskeletal organization
13. Keratinocyte migration is partially supported by the cell-binding domain of fibronectin and is RGDS-dependent
14. Keratinocyte integrins
15. Integrin-ligand binding prop erties govern cell migration speed through cell-substratum ad hesiveness
16. Cell adhesion and motility depend on nanoscale RGD clustering
17. Epidermal growth factor alters fibroblast migration speed and directional persistence reciprocally and in a matrix-dependent manner
18. Neural crest cell locomotion induced by antibodies to β1 integrins
19. Mathematical model for the effects of adhesion and mechanics on cell migration speed
20. Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength
21. Physical and biochemical regulation of integrin release during rear detachment of migrating cells
22. Self-polarization and directional motility of cytoplasm
23. Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages
24. Forces on adhesive contacts affect cell function
25. Integrin and signal transduction pathways: The road taken
26. Adhesion in cell migration
27. Signal transduction in cell-matrix interactions
28. Focal adhesion assembly
29. Selective regulation of integrin-cytoskeleton interactions by the tyrosine kinase
30. Origins of cell polarity
31. Role of p120 Ras-GAP in directed cell movement
32. Integrin-mediated adhesion regulates cell polarity and membrane protrusion through the Rho family of GTPases
33. 5) and their relationship with the cytoskeleton and basement membrane matrix in cultured human keratinocytes
34. Graded fibronectin receptor aggregation in migrating cells
35. The locomotion of fibroblasts in culture: I. Movements of the leading edge
36. The locomotion of fibroblasts in culture: III. Movements of particles on the dorsal surface of the leading lamella
37. Quantifying lamella dynamics of cultured cells by SACED, a new computer-assisted motion analysis
38. Actin-dependent lamellipodia formation and microtubule-dependent tail retraction control directed cell migration
39. Serial cultivation of strains of human epidermal keratinocytes: The formation of keratinizing colonies from single cells
40. Growth of cultured human epidermal cell into multiple epithelia suitable for grafting
41. Calcium regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture
42. Quantitative relationship among integrin-ligand binding, adhesion, and signaling via focal adhesion kinase and extracellular signal-regulated kinase 2
43. Cell attachment activity of fibronectin can duplicated by small synthetic fragments of the molecule
44. Mechanotransduction across cell surface and through the cytoskeleton
45. Role of integrins in cellular response to mechanical stress and adhesion
46. Cellular control lies in the balance of forces
47. Mechanics of fibroblast locomotion: Quantitative analysis of forces and motions at the leading lamellas of fibroblasts
48. Rho GTPases and the actin cytoskeleton
49. Comparison of actin and cell surface dynamics in motile fibroblasts
50. Focal adhesions, contractility, and signaling
51. Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells
52. Spreading and enhanced motility of human keratinocytes on fibronectin
53. The effect of fibronectin on the migration of keratinocytes
54. Cell migration: A physically integrated molecular process