Nucleotide diversity of the TNF gene region in an African village

Genes and Immunity

Volumn 2, Issue 6, 2001, Pages 343-348

  Richardson, A ^d   Sisay Joof, F ^a   Ackerman, H ^d   Usen, S ^a   Katundu, P ^b   Taylor, T ^b   Molyneux, M ^b   Pinder, M ^a   Kwiatkowski, D ^c  

^a MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

^b UNIVERSITY OF MALAWI   (Malawi)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d NONE

Author keywords

Malawi; The Gambia; TNF gene

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; ALLELE; ARTICLE; CHILD; FEMALE; GAMBIA; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENETICS; GENOTYPE; HUMAN; MALAWI; MALE; NEGRO; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; RISK; RURAL POPULATION;

ADOLESCENT; ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; ALLELES; CHILD; CHILD, PRESCHOOL; DNA MUTATIONAL ANALYSIS; FEMALE; GAMBIA; GENE FREQUENCY; GENOTYPE; HUMANS; MALAWI; MALE; ODDS RATIO; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RURAL POPULATION; TUMOR NECROSIS FACTOR-ALPHA; VARIATION (GENETICS);

EID: 0035486994     PISSN: 14664879     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gene.6363789     Document Type: Article

References (29)

1. Complete sequence and gene map of a human major histocompatibility complex. The MHC sequencing consortium [In Process Citation]. Nature 1999; 401: 921-923.
2. McGuire W, Hill AV, Allsopp CE, Greenwood BM, Kwiatkowski D. Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. Nature 1994; 371: 508-510.
3. Cabrera M, Shaw MA, Sharples CJ et al. Polymorphism in tumor necrosis factor genes associated with mucocutaneous leishmaniasis. J Exp Med 1995; 182: 1259-1264.
4. Nadel S, Newport MJ, Booy R, Levin M. Variation in the tumor necrosis factor-alpha gene promoter region may be associated with death from meningococcal disease. J Infect Dis 1996; 174: 878-880.
5. Conway DJ, Holland MJ, Bailey RL et al. Scarring trachoma is associated with polymorphism in the tumor necrosis factor alpha (TNF-alpha) gene promoter and with elevated TNF-alpha levels in tear fluid. Infect Immun 1997; 65: 1003-1006.
6. McGuire W, Knight JC, Hill AV, Allsopp CE, Greenwood BM, Kwiatkowski D. Severe malarial anemia and cerebral malaria are associated with different tumor necrosis factor promoter alleles. J Infect Dis 1999; 179: 287-290.
7. Knight JC, Udalova I, Hill AV et al. A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria. Nat Genet 1999; 22: 145-150.
8. Knight JC, Kwiatkowski D. Inherited variability of tumor necrosis factor production and susceptibility to infectious disease. Proc Assoc Am Physicians 1999; 111: 290-298.
9. Moffatt MF, Cookson WO. Tumour necrosis factor haplotypes and asthma. Hum Mol Genet 1997; 6: 551-554.
10. Fernandez-Arquero M, Arroyo R, Rubio A et al. Primary association of a TNF gene polymorphism with susceptibility to multiple sclerosis. Neurology 1999; 53: 1361-1363.
11. Negoro K, Kinouchi Y, Hiwatashi N et al. Crohn's disease is associated with novel polymorphisms in the 5′-flanking region of the tumor necrosis factor gene. Gastroenterology 1999; 117: 1062-1068.
12. Westendorp RG, Langermans JA, Huizinga TW et al. Genetic influence on cytokine production and fatal meningococcal disease [published erratum appears in Lancet 1997; 349: 656]. Lancet 1997; 349: 170-173.
13. Cargill M, Altshuler D, Ireland J et al. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet 1999; 22: 231-238.
14. Hill AV, Allsopp CE, Kwiatkowski D et al. Common West African HLA antigens are associated with protection from severe malaria. Nature 1991; 352: 595-600.
15. Nedospasov SA, Shakhov AN, Turetskaya RL et al. Tandem arrangement of genes coding for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) in the human genome. Cold Spring Harb Symp Quant Biol 1986; 51: 611-624.
16. Wright S. Systems of mating. Genetics 1921; 6: 111-178.
17. Halushka MK, Fan JB, Bentley K et al. Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. Nat Genet 1999; 22: 239-247.
18. Hill AV, Allsopp CE, Kwiatkowski D et al. Extensive genetic diversity in the HLA class II region of Africans, with a focally predominant allele, DRB1*1304. Proc Natl Acad Sci USA 1992; 89: 2277-2281.
19. Goddard KA, Hopkins PJ, Hall JM, Witte JS. Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations. Am J Hum Genet 2000; 66: 216-234.
20. Kawasaki A, Tsuchiya N, Hagiwara K, Takazoe M, Tokunaga K. Independent contribution of HLA-DRB1 and TNF alpha promoter polymorphisms to the susceptibility to Crohn's disease. Genes Immun 2000; 1: 351-357.
21. Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci USA 1997; 94: 3195-3199.
22. Abraham LJ, Kroeger KM. Impact of the -308 TNF promoter polymorphism on the transcriptional regulation of the TNF gene: relevance to disease. J Leukoc Biol 1999; 66: 562-566.
23. Brinkman BM, Zuijdeest D, Kaijzel EL, Breedveld FC, Verweij CL. Relevance of the tumor necrosis factor alpha (TNF alpha) -308 promoter polymorphism in TNF alpha gene regulation. J Inflamm 1995; 46: 32-41.
24. Stuber F, Udalova IA, Book M et al. -308 tumor necrosis factor (TNF) polymorphism is not associated with survival in severe sepsis and is unrelated to lipopolysaccharide inducibility of the human TNF promoter. J Inflamm 1996; 46: 42-50.
25. Hohjoh H, Tokunaga K. Allele-specific binding of the ubiquitous transcription factor OCT-1 to the functional single nucleotide polymorphism (SNP) sites in the tumor necrosis factor-alpha gene (TNFA) promoter. Genes Immun 2001; 2: 105-109.
26. Udalova IA, Richardson A, Denys A et al. Functional consequences of a polymorphism affecting NF-kappaB p50-p50 binding to the TNF promoter region. Mol Cell Biol 2000; 20: 9113-9119.
27. Higuchi T, Seki N, Kamizono S et al. Polymorphism of the 5′-flanking region of the human tumor necrosis factor (TNF)-alpha gene in Japanese. Tissue Antigens 1998; 51: 605-612.
28. Skoog T, van't Hooft FM, Kallin B et al. A common functional polymorphism (C → A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-alpha) gene associated with reduced circulating levels of TNF-alpha. Hum Mol Genet 1999; 8: 1443-1449.
29. Uglialoro AM, Turbay D, Pesavento PA et al. Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-alpha gene promoter. Tissue Antigens 1998; 52: 359-367.