IL-10 inhibits granulocyte-macrophage colony-stimulating factor-dependent human monocyte survival at the early stage of the culture and inhibits the generation of macrophages

Journal of Immunology

Volumn 167, Issue 7, 2001, Pages 3619-3625

  Hashimoto, S I ^a   Komuro, I ^a   Yamada, M ^a   Akagawa, K S ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 0035478332     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.7.3619     Document Type: Article

References (38)

1. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cylokine production by Thl clones
2. Interleukin 10 (IL-10) inhibits cylokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
3. Macrophage deactivation by interleukin 10
4. IL-10 stimulates monocyle FeγR surface expression and cytotoxicity activity: Distinct regulation of antibody-dependent cellular cytotoxicity by IFN-γ IL-4, and IL-10
5. Interleukin-10 drives human monocytes to CD16 positive macrophages
6. Interleukin 10, a novel B cell stimulatory factor: Unresponsiveness of X chromosome linked immunodeficiency B cells
7. IL10, a novel growth cofactor for mature and immature T cells
8. Interleukin 10: A novel stimulatory factor for masl cells and their progenitors
9. IL-10 inhibits apoptolic cell death in human T cells starved of IL-2
10. Interleukin-10 prevents, spontaneous death of germinal center B cell by induction of the bcl-2 protein
11. Enhancement of macrophage-colony stimulating factor-induced growth and differentiation of human monocytes by interleukin-10
12. Suppression of HIV replication in human monocyte-derived macrophages induced by granulocyte/macrophage colony-stimulating factor
13. + dendritic cells and tartrate-resistant acid phosphatase-positive osteoclast-like multinucleated giant cells form human monocytes
14. Comparison of the effects of IL-3, granulocyte-macrophage colony-stimulating factor, and macrophage colony stimulating factor in supporting monocyte differentiation in culture: Analysis of macrophage antibody-dependent cellular cytotoxicity
15. A simple method for counting adherent cells: Application to cultured human monocytes, macrophages and multinucleated giant cells
16. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
17. Gene induction by γ-irradiation leads to DNA fragmentation in lymphocyte
18. Quantitative analysis of the two macrophage colony-stimulating factor mRNA expressed in a human stromat cell line by reverse transcription polymera chain reaction (RT-PCR)
19. Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoplotic cell death
20. JAK2 associates with the β chain of the receptor for granulocyte macrophage colony-stimulating factor, and its activation requires the membrane-proximal region
21. Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through STAT5 homologs
22. Signal transduction by the high-affinity GM-CSF receptor: Two distinct cytoplasmic regions of the common β subunit responsible for different signaling
23. Suppression of apoptotic death in hematopoietic cells by signaling through the IL-3/GM-CSF
24. 694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription
25. Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers th prolactin response
26. Interleukin-10 inhibits spontaneous colony-forming unit-granulocyte-macrophoge growth from human peripheral blood mononuclear cells by suppression of endogenous granulocyte-macrophage colony-stimulating factor release
27. Colony-stimulating factor I-induced STAT1 and STAT3 activation is accompanied by phosphorylation of Tyk2 in macrophages and Tyk2 and JAK1 in fibroblasts
28. IL-10 induces the tyrosine phosphorylation of tyk2 and Jak and the differential assembly of STAT1 and STAT3 complexes in human T cells and monocytes
29. IFN-g and IL-10 inhibit induction of IL-1 receptor type 1 and type 11 gene expression by IL-4 and IL-13 in human monocytes
30. αταρκ are involved in IL-10-mediated selective repression of TNF-α-induced activation and maturation of human peripheral blood monocyle-derived dendritie cells
31. Cylokinespecific activation of distinct mitogen-acrivated protein kinase subtype cascades in human neutrophils stimulated by granulocyte-colony-stimulating factor, granulocyle-macrophage colony-stimulating factor, and tumor necrosis factor-α
32. Monocyte deactivation by interleukin 10 via inhibition of tyrosine kinase activity and the ras signaling pathway
33. KB) activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms
34. Critical role of Lyn kinase in inhibition of neutrophil apoptosis by granulocyte-macrophage colony-stimulating factor
35. Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils
36. Expression of the macrophage-specific colony-stimulating factor in human monocytes treated with granulocytemacrophage colony-stimulating factor
37. Production of macrophage colony-stimulating factor (M-CSF) by human monocytes is differentially regulated by GMCSF. TNFα, and IFN-γ
38. IL-10 contributes to development of macrophage suppressor activities by macrophage colony-stimulating factor, but not by granulocyte-macrophage colony-stimulating factor