Interleukin-10 inhibits spontaneous colony-forming unit-granulocyte- macrophage growth from human peripheral blood mononuclear cells by suppression of endogenous granulocyte-macrophage colony-stimulating factor release

Blood

Volumn 89, Issue 4, 1997, Pages 1147-1153

  Oehler, Leopold ^b   Foedinger, Manuela ^b   Koeller, Markus ^b   Kollars, Marietta ^b   Reiter, Elisabeth ^b   Bohle, Barbara ^b   Skoupy, Sonja ^b   Fritsch, Gerhard ^b   Lechner, Klaus ^b   Geissler, Klaus ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CD3 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; METHYLCELLULOSE; NEUTRALIZING ANTIBODY;

ARTICLE; CELL GROWTH; CELL INTERACTION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DOSE RESPONSE; GRANULOCYTE; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOPATHOGENESIS; MACROPHAGE FUNCTION; MONONUCLEAR CELL; PERIPHERAL VASCULAR SYSTEM; PRIORITY JOURNAL;

EID: 0031055375     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v89.4.1147     Document Type: Article

References (36)

1. Metcalf D: The molecular control of cell division, .differentiation commitment and maturation in haematopoietic cells. Nature 339:27, 1989
2. Chervenick PA, LoBuglio: Human blood monocytes: Stimulators of granulocyte and mononuclear colony formation in vitro. Science 178:164, 1972
3. Broxmeyer HE, Williams DE: The production of myeloid cells and their regulation during health and disease. Crit Rev Oncol Hematol 8:173, 1988
4. Ferrero D, Tarella C, Badoni R, Caracciolo D, Bellone G, Pileri A, Gallo E: Granulocyte-macrophage colony-stimulating factor requires interaction with accessory cells or granulocyte-colony stimulating factor for full stimulation of human myeloid progenitors. Blood 73:402, 1989
5. Schreier MH, Iscove NN: Haematopoietic growth factors are released in cultures of H-2-restricted helper T cells, accessory cells and specific antigen. Nature 287:228, 1980
6. Bagby GC, Vasiliki, Rigas D, Bennett RM, Vandenbark AA, Garewal HS: Interaction of lactoferrin, monocytes, and T lymphocyte subsets in the regulation of steady-state granulopoiesis in vitro. J Clin Invest 68:56, 1981
7. Schibler KR, Li Y, Ohls RK, Nye NC, Durham MC, White W, Liechty KW, Trong Le, Christensen RD: Possible mechanisms accounting for the growth factor independence of hematopoietic progenitors from umbilical cord blood. Blood 84:3679, 1994
8. Geissler K, Hinterberger W, Bettelheim P, Haas O, Lechner K: Colony growth characteristics in chronic myelomonocytic leukemia. Leuk Res 12:373, 1988
9. Estrov Z, Grunberger T, Chan HSL, Freedman MH: Juvenile chronic myelogenous leukemia: Characterization of the/disease using cell cultures. Blood 67:1382, 1986
10. Murohashi I, Tohda S, Suzuki T, Nagata K, Yamashita Y, Nara N: Autocrine growth mechanisms of the progenitors of blast cells in acute myeloblastic leukemia. Blood 74:35, 1989
11. Fiorentino DF, Bond MW, Mosmann TR: Two types of mouse helper T cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 170:2081, 1989
12. De Waal Malefyt R, Abrams J, Bennet B, Figdor C, de Vries J: IL-10 inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes. J Exp Med 174:1209, 1991
13. Miltenyi S, Müller W, Weichel W, Radbruch A: High gradient magnetic cell separation with MACS. Cytometry 11:231, 1990
14. + myeloid progenitors using CD45-RA analysis. Blood 81:2301, 1993
15. Chomczynski P, Sacchi N: Single-step method of RNA isola-tion by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
16. Mitterbauer G, Foedinger M, Scherrer R, Knoebel P, Jaeger U, Laczika K, Schwarzinger I, Gaiger A, Geissler K, Greinix H, Kahls P, Linkesch W, Lechner K, Mannhalter Ch: PCR-monitoring of minimal residual leukemia after conventional chemotherapy and bone marrow transplantation in BCR-ABL positive acute lymphoblastic leukemia. Br J Haematol 89:937, 1995
17. Russel ME, Adamd DH, Wyner LR, Yamashita Y, Halnon NJ, Karnovsky MJ: Early and persistent induction of monocyte che-moattractant protein in rat cardiac allografts. Proc Natl Acad Sci USA 90:6086, 1993
18. Khoury SJ, Gallon L, Chen W, Betres K, Russel ME, Hancock WW, Carpenter CB, Sayegh MH, Weiner HL: Mechanism of acquired thymic tolerance in experimental autoimmune encephalomyelitis: Thymic dentritic-enriched cells induce specific peripheral T cell unresponsiveness in vivo. J Exp Med 182:357, 1995
19. Miyatake S, Otsuka T, Yokota T, Lee F, Arai K: Structure of the chromosomal gene tor granulocyte-macrophage colony stimulating factor: Comparison of the mouse and human genes. EMBO J 4:2561, 1985
20. Ding L, Shevach EM: IL-10 inhibits mitogen-induced T cell proliferation by selectively inhibiting macrophage costimulatory function. J Immunol 148:3133, 1992
21. Gazzinelli RT, Oswald IP, James SL, Sher A: IL-10 inhibits parasite killing and nitrogen oxide production by INF-γ activated macrophages. J Immunol 148:1792, 1992
22. Oswald I, Gazzinelli RT, Sher A, James SL: IL-10 synergizes with IL-4 and transforming growth factor-β to inhibit macrophage cytotoxic activity. J Immunol 148:3578, 1992
23. Howard M, Muchamel T, Andrade S, Menon S: Interleukin-10 protects mice from lethal endotoxemia. J Exp Med 177:1205, 1993
24. Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W: Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75:263, 1993
25. Ruscetti FW, Chervenick PA: Release of colony-stimulating activity from thymus-derived lymphocytes. J Clin Invest 55:520, 1975
26. Geissler D, Konwalinka G, Peschl C, Grünewald K, Odavic R, Braunsteiner H: A regulatory role of activated T lymphocytes on human megakaryocytopoiesis in vitro. Br J Haematol 60:233, 1984
27. Boyum A: Separation of white blood cells. Nature 204:793, 1964
28. Buchmeier NA, Schreiber RD: Requirement of endogenous interferon-γ production for resolution of Listeria monocytogenes infection. Proc Natl Acad Sci USA 82:7404, 1985
29. Chikkappa G, Phillips PG: Regulation of normal human blood neutrophilic, macrophagic, and eosinophilic committed stem cell proliferation by autologous blood T lymphocyte subsets. Blood 63:356, 1984
30. Broxmeyer HE, DeSousa M, Smithyman A, Ralph P, Hamilton J, Kurland JI, Bognacki J: Specificity and modulation of the action of lactoferrin, a negative feedback regulator of myelopoiesis. Blood 55:324, 1980
31. Ganser A, Carlo-Stella C, Greher J, Volkers B, Hoelzer D: Effect of recombinant interferons alpha and gamma on human bone marrow-derived megakaryocytic progenitor cells. Blood 70:1173, 1987
32. Lu L, Foa P, Chillemi F, Shen RN, Lin ZH, Carow C, Broxmeyer HE: Suppressive biological activity of a synthetic pentapeptide on highly enriched human and murine marrow hematopoietic progenitors: Synergism with recombinant human tumor necrosis factor-alpha and interfcron-gamma. Exp Hematol 17:935, 1989
33. + stem cells. Exp Hematol 22:136, 1994
34. Taga K, Mostowski H, Tosato G: Human interleukin-10 can directly inhibit T-cell growth. Blood 81:2964, 1993
35. + T cell clones and resting T cells. J Immunol 150:4754, 1993
36. Geissler K, Öhler L, Födinger M, Virgolini I, Leimer M, Kabrna E, Kollars M, Skoupy S, Bohle B, Rogy M, Lechner K: Interleukin-10 inhibits growth and granulocyte/macrophage colonystimulating factor production in chronic myelomonocytic leukemia cells. J Exp Med 184:1377, 1996