Modulation of angiogenesis and tumorigenicity of human melanocytic cells by vascular endothelial growth factor and basic fibroblast growth factor

Cancer Research

Volumn 61, Issue 19, 2001, Pages 7282-7290

  Graeven, Ullrich ^a   Karpinski, Sonja ^a   Schmiegel, Wolff ^a   Jost, Monika ^c   Rodeck, Ulrich ^c  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b Augusta Kranken Anstalt   (Germany)

^c Thomas Jefferson University   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CYTOKINE; FIBROBLAST GROWTH FACTOR 2; THROMBOSPONDIN 1; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CANCER GROWTH; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE OVEREXPRESSION; GROWTH STIMULATION; HUMAN; HUMAN CELL; MELANOCYTE; MELANOMA; MELANOMA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKIN CARCINOGENESIS;

ANIMALS; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOKINES; MELANOCYTES; MELANOMA; MICE; MICE, SCID; NEOVASCULARIZATION, PATHOLOGIC; TRANSFECTION; TRANSGENES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0035476838     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Melanoma-associated expression of vascular endothelial growth factor and its receptors FLT-1 and KDR
2. Proliferation of human malignant melanomas is inhibited by antisense oligodeoxynucleotides targeted against basic fibroblast growth factor
3. Inhibition of the fibroblast growth factor receptor 1 (FGFR-1) gene in human melanocytes and malignant melanomas leads to inhibition of proliferation and signs indicative of differentiation
4. Expression patterns of placenta growth factor-1 in human melanocytic cell lines
5. Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGF-like growth factor
6. Constitutive expression of multiple growth factor genes by melanoma cells but not normal melanocytes
7. Characterization of tenascin secreted by human melanoma cells
8. In vitro properties of human melanoma cells metastatic in nude mice
9. Expression of plasminogen activators and plasminogen activator inhibitors in cutaneous melanomas of transgenic melanoma-susceptible mice
10. Coordinated expression of the vitronectin receptor and the urokinase-type plasminogen activator receptor in metastatic melanoma cells
11. Melanoma-mediated dissolution of extracellular matrix: Contribution of urokinase-dependent and metalloproteinase-dependent proteolytic pathways
12. CD44/chondroitin sulfate proteoglycan and α2β1 integrin mediate human melanoma cell migration on type IV collagen and invasion of basement membranes
13. Involvement of CD44 in matrix metalloproteinase-2 regulation in human melanoma cells
14. Vascular endothelial growth factor (VEGF) and its receptors
15. Spatial and temporal expression of angiogenic molecules during tumor growth and progression
16. Vascular endothelial growth factor expression in malignant melanoma: Prognostic versus diagnostic usefulness
17. Expression of basic fibroblast growth factor and vascular endothelial growth factor in primary and metastatic melanoma from the same patients
18. Isolation and partial molecular characterization of pituitary fibroblast growth factor
19. Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: An autocrine mechanism contributing to angiogenesis
20. Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
21. Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo
22. Cooperative effect of TNFα, bFGF, and VEGF on the formation of tubular structures of human microvascular endothelial cells in a fibrin matrix. Role of urokinase activity
23. Vascular endothelial growth factor (VEGF)-C synergizes with basic fibroblast growth factor and VEGF in the induction of angiogenesis in vitro and alters endothelial cell extracellular proteolytic activity
24. Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes
25. Transformation of murine melanocytes by basic fibroblast growth factor cDNA and oncogenes and selective suppression of the transformed phenotype in a reconstituted cutaneous environment
26. SV40-transfected human melanocyte sensitivity to growth inhibition by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate
27. Cloning, structure and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
28. Negative regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells via a retinoic acid response element
29. Induction of vascular endothelial growth factor by tumor necrosis factor α in human glioma cells. Possible roles of SP-1
30. Melanoma cell lines express VEGF receptor KDR and respond to exogenously added VEGF
31. Two independent mechanisms essential for tumor angiogenesis: Inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway
32. Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function
33. Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors
34. Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis
35. Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinoma
36. Vascular permeability factor expression influences tumor angiogenesis in human melanoma lines xenografted to nude mice
37. Induction of growth factor RNA expression in human malignant melanoma: Markers of transformation
38. Suppression of autocrine cell proliferation and tumorigenesis of human melanoma cells and fibroblast growth factor transformed fibroblasts by a kinase-deficient FGF receptor 1: Evidence for the involvement of Src-family kinases
39. Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis
40. Tumor growth modulation by sense and antisense vascular endothelial growth factor gene expression: Effects on angiogenesis, vascular permeability, blood volume, blood flow, fluorodeoxyglucose uptake, and proliferation of human melanoma intracerebral xenografts
41. Basic fibroblast growth factor induces a transformed phenotype in normal human melanocytes
42. Molecular mediators of angiogenesis in bladder cancer
43. Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1
44. Vascular channel formation by human melanoma cells in vivo and in vitro: Vasculogenic mimicry