Investigation of the dNTP-binding site of HIV-1 reverse transcriptase using photoreactive analogs of dNTP

Biochemistry (Moscow)

Volumn 66, Issue 9, 2001, Pages 999-1007

  Zakharenko, A L ^a   Kolpashchikov, D M ^a   Khodyreva, S N ^a   Lavrik, O I ^a   Menendez Arias L ^b  

^a INSTITUTE OF CHEMICAL BIOLOGY AND FUNDAMENTAL MEDICINE   (Russian Federation)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

DNTP binding; HIV 1 reverse transcriptase; Photosensitizing modification

Indexed keywords

2',3' DIDEOXYURIDINE 5' TRIPHOSPHATE; 2',3'-DIDEOXYURIDINE-5'-TRIPHOSPHATE; 5 (N (2,3,5,6 TETRAFLUORO 4 AZIDOBENZOYL)AMINOPROPENYL 1) 2' DEOXYURIDINE 5' TRIPHOSPHATE; 5-(N-(2,3,5,6-TETRAFLUORO-4-AZIDOBENZOYL)AMINOPROPENYL-1)-2'-DEOXYURIDINE-5'-TRIPHOSPHATE; ALANINE; DEOXYURIDINE PHOSPHATE; DEOXYURIDINE TRIPHOSPHATE; MAGNESIUM; MANGANESE; PYRIMIDINE NUCLEOTIDE; RNA DIRECTED DNA POLYMERASE; TRYPTOPHAN; TYROSINE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CHEMISTRY; ENZYME ACTIVE SITE; GENETICS; KINETICS; METABOLISM; METHODOLOGY; PHOTOAFFINITY LABELING; PHOTOCHEMISTRY; ULTRAVIOLET RADIATION;

ALANINE; AMINO ACID SUBSTITUTION; BINDING SITES; CATALYTIC DOMAIN; DEOXYURACIL NUCLEOTIDES; HIV-1 REVERSE TRANSCRIPTASE; KINETICS; MAGNESIUM; MANGANESE; PHOTOAFFINITY LABELS; PHOTOCHEMISTRY; TRYPTOPHAN; TYROSINE; ULTRAVIOLET RAYS; URACIL NUCLEOTIDES;

EID: 0035437685     PISSN: 00062979     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012373626717     Document Type: Article

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