Confirmation of susceptibility gene loci on chromosome 1 in Northern China Han families with type 2 diabetes

Chinese Medical Journal

Volumn 114, Issue 8, 2001, Pages 876-878

  Du, Weinan ^a   Sun, Hongxia ^a   Wang, Heng ^b   Qiang, Boqin ^c   Shen, Yan ^c   Yao, Zhijian ^c   Gu, Jun ^c   Xiong, Momiao ^a   Huang, Wei ^c   Chen, Zhu ^c   Zuo, Jin ^a   Hua, Xiufeng ^d   Gao, Wei ^d   Sun, Qi ^b   Fang, Fude ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^c CHINESE NATIONAL HUMAN GENOME CENTER AT SHANGHAI   (China)

^d YANTAI YUHUANGDING HOSPITAL   (China)

Author keywords

Gene mapping; Genome screening; Microsatellte markers; Susceptibility genes; Type 2 diabetes

Indexed keywords

MICROSATELLITE DNA;

ARTICLE; CHROMOSOME 1; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HUMAN; NON INSULIN DEPENDENT DIABETES MELLITUS;

CHROMOSOMES, HUMAN, PAIR 1; DIABETES MELLITUS, TYPE 2; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LOD SCORE; MICROSATELLITE REPEATS;

EID: 0035436349     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Zhao JY, Wang H, Xiong MM, et al. The localization of type 2 diabetes susceptibility gene loci in northern Chinese Han families. Chin Sci Bull 2000;45:1792-1795.
2. Zhao JY, Wang H, Zuo J, et al. Genotyping and mapping of type 2 diabetes in Chinese. Acta Anatomica Sinica 1999;30:292-298.
3. Kruglyak L, Daly MJ, Reeve-Daly MP, et al. Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 1996;58:1347-1363.
4. Hanis CL, Boerwinkle E, Chankraborty R, et al. A genomewide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nature Genet 1996;13:161-166.
5. Mahtani MM, Widen E, Lehto M, et al. Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families. Nature Genet 1996;14:90-94.
6. Ghosh S, Hauser E, Magnuson VL, et al. A large sample of finnish diabetic sib-pairs reveals no evidence for a non-insulin-dependent diabetes mellitus susceptibility locus at 2qter. J Clin Invest 1998;102:704-709.
7. Ghosh S, Watanabe R, Hauser E, et al. Type 2 diabetes: evidence for linkage on chromosome 20 in 716 finnish affected sibpairs. Proc Natl Acad Sci U S A 1999;96:2198-2203.
8. Elbein SC, Hoffman MD, Teng K, et al. A genome-wide search for type 2 diabetes susceptibility genes in Utah Caucasians. Diabetes 1999;48:1175-1182.