Rejection of mouse cardiac allografts by costimulation in trans

Journal of Immunology

Volumn 167, Issue 3, 2001, Pages 1174-1178

  Mandelbrot, D A ^a   Kishimoto, K ^a   Auchincloss H , Jr ^a   Sharpe, A H ^a   Sayegh, M H ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; GRAFT REJECTION; HEART GRAFT; IMMUNE RESPONSE; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0035421871     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.167.3.1174     Document Type: Article

References (20)

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3. T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo
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5. From TCR engagement to T cell activation: A kinetic view of T cell behavior
6. Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells
7. Activation of CD4+ T cells by delivery of the B7 costimulatory signal on bystander antigen-presenting cells (trans-costimulation)
8. The role of "indirect" recognition in initiating rejection of skin grafts from major histocompatibility complex class II-deficient mice
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10. B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation
11. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan destruction, revealing a critical negative regulatory role of CTLA-4
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13. In vivo use of monoclonal antibodies against murine T cell antigens
14. + cells stimulated indirectly, cause rejection of "major histocompatibility complex-deficient" skin grafts
15. Allogeneic non-T spleen cells restore the responsiveness of normal T cell clones stimulated with antigen and chemically modified antigen-presenting cells
16. B7 but not ICAM-1 costimulation prevents the induction of human alloantigen specific tolerance
17. A cell culture model for T lymphocyte clonal anergy
18. B7/CD28 but not LFA-3/CD2 interactions can provide 'third-party' co-stimulation for human T-cell activation
19. Quantifying the frequency of alloreactive T cells in vivo: New answers to an old question
20. High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: Mechanisms of selection of the self-reactive repertoire