Altering the fine specificity of an anti-Legionella single chain antibody by a single amino acid insertion

Journal of Immunological Methods

Volumn 251, Issue 1-2, 2001, Pages 137-149

  McCarthy, Barry J ^a   Hill, Amanda S ^a  

^a CSIRO   (Australia)

Author keywords

Complementarity determining region; Legionella; Salt bridge; scFv; Site directed mutagenesis

Indexed keywords

ASPARTIC ACID; IMMUNOGLOBULIN HEAVY CHAIN; MONOCLONAL ANTIBODY; RECOMBINANT ANTIBODY;

AMINO ACID SEQUENCE; ANTIBODY SPECIFICITY; ARTICLE; COMPLEMENTARITY DETERMINING REGION; IMMUNOGLOBULIN VARIABLE REGION; LEGIONELLA; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BASE SEQUENCE; BLOTTING, WESTERN; CLONING, MOLECULAR; COMPLEMENTARITY DETERMINING REGIONS; DNA PRIMERS; DNA, RECOMBINANT; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; GENE EXPRESSION; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; LEGIONELLA PNEUMOPHILA; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; MUTAGENESIS, SITE-DIRECTED; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

LEGIONELLA;

EID: 0035342475     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(00)00319-7     Document Type: Article

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