Non-receptor protein tyrosine kinases and phosphatases in human platelets

Thrombosis and Haemostasis

Volumn 76, Issue 5, 1996, Pages 640-650

  Jackson, Shaun P ^a   Schoenwaelder, Simone M ^a   Yuan, Yuping ^a   Salem, Hatem H ^a   Cooray, Prasad ^a  

^a BOX HILL HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN; CELL SURFACE RECEPTOR; ENZYME; PHOSPHATASE; PROTEIN TYROSINE KINASE;

CONTROLLED STUDY; ENZYME STRUCTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW; THROMBOCYTE;

EID: 0029911291     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0038-1650637     Document Type: Review

References (151)

1. Parsons JT, Parsons SJ. Protein-tyrosine kinases, oncogenes, and cancer. Important Adv Oncol 1993; 3-17.
2. Fantl WJ, Johnson DE, Williams LT. Signalling by receptor tyrosine kinases. Annu Rev Biochem 1993; 62: 453-81.
3. Ullrich A, Schlessinger J. Signal transduction by receptors with tyrosine kinase activity. Cell 1990; 61: 203-12.
4. Cantley LC, Auger KR, Carpenter C, Duckworth B, Graziani A, Kapeller R, Soltoff S. Oncogenes and signal transduction. Cell 1991; 64: 281-302.
5. c-src family of protein-tyrosine kinases: Structure, regulation and function. Crit Rev Oncogen 1992; 3: 401-46.
6. Rudd CE, Janssen O, Prasad KVS, Raab M, da Silva A, Telfer JC, Yamamoto M. src-related protein tyrosine kinases and their surface receptors. Biochim Biophys Acta 1993; 1155: 239-66.
7. Vassbotn FS, Havnen OK, Heldin CH, Holmsen H. Negative feedback regulation of human platelets via autocrine activation of the platelet-derived growth factor alpha-receptor. J Biol Chem 1994; 269: 13874-9.
8. Fischer EH, Charbonneau H, Tonks NK. Protein tyrosine phosphatases: A diverse family of intracellular and transmembrane enzymes. Science 1991; 253: 401-6.
9. Feng G, Pawson T. Phosphotyrosine phosphatases with SH2 domains: regulators of signal transduction. Trends Genet 1994; 10: 54-8.
10. Sun H, Tonks NK. The coordinated action of protein tyrosine phosphatases and kinases in cell signaling. TIBS 1994; 19: 480-5.
11. c-src-specific tyrosine kinase activity. Proc Natl Acad Sci 1986; 83: 852-6.
12. Golden A, Brugge JS. Thrombin treatment induces rapid changes in tyrosine phosphorylation in platelets. Proc Natl Acad Sci USA 1989; 86: 901-5.
13. Ferrell JE, Martin GS. Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in platelets. Proc Natl Acad Sci USA 1989; 86: 2234-38.
14. Bachelot C, Cano E, Grelac F, Saleun S, Druker BJ, Lévy-Toledano S, Fischer S, Rendu F. Functional implications of tyrosine protein phosphorylation in platelets. Biochem J 1992; 284: 923-8.
15. Nakamura S, Yamamura H. Thrombin and collagen induce rapid phosphorylation of a common set of cellular proteins on tyrosine in human platelets. J Biol Chem 1989; 264: 7089-91.
16. Jackson SP, Schoenwaelder SM, Yuan Y, Rabinowitz I, Salem HH, Mitchell CA. Adhesion receptor activation of phosphatidylinositol 3-kinase. J Biol Chem 1994; 269: 27093-9.
17. Razdan K, Hellums JD, Kroll MH. Shear-stress-induced von Willebrand factor binding to platelets causes the activation of tyrosine kinase(s). Biochem J 1994; 302: 681-6.
18. c-src, phospholipase C, inositol-lipid, and diacylglycerol kinases with the cytoskeletons of thrombin-stimulated platelets. J Biol Chem 1991; 266: 15705-9.
19. Guinebault C, Payrastre B, Racaud-Sultan C, Mazarguil H, Breton M, Mauco G, Plantavid M, Chap H. Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85α with actin filaments and focal adhesion kinase. J Cell Biol 1995; 129: 831-42.
20. syk to the cytoskeleton in thrombin-stimulated platelets. J Biol Chem 1994; 269: 32796-9.
21. 3 through cytoskeletal reorganisation and tyrosine phosphorylation in human platelets. J Biol Chem 1995; 270: 11927-34.
22. Law DA, Nannizzi-Alaimo L, Phillips DR. Outside-in integrin signal transduction. J Biol Chem 1996; 271: 10811-5.
23. Vostal JG, Shulman NR. Vinculin is a major platelet protein that undergoes calcium-dependent tyrosine phosphorylation. Biochem J 1993; 294: 675-80.
24. Daniel JL, Dangelmaier C, Smith JB. Evidence for a role for tyrosine phosphorylation of phospolipase Cγ2 in collagen-induced platelet cytosolic calcium mobilisation. Biochem J 1994; 302: 617-22.
25. FAK in platelets. J Cell Biol 1992; 119: 905-12.
26. Rendu F, Eldor A, Grelac F, Bachelot C, Gazit A, Gilon C, Levy-Toledano S, Levitzki A. Inhibition of platelet activation by tyrosine kinase inhibitors. Biochem Pharmacol 1992; 44: 881-8.
27. Salari H, Duronio V, Howard SL, Demos M, Jones K, Reany A, Hudson AT, Pelech SL. Erbstatin blocks platelet activating factor-induced protein-tyrosine phosphorylation, phosphoinositide hydrolysis, protein kinase C activation, serotonin secretion and aggregation of rabbit platelets. FEBS Letts 1990; 263: 104-8.
28. Gaudette DC, Holub BJ. Effect of genistein, a tyrosine kinase inhibitor, on U46619-induced phosphoinositide phosphorylation in human platelets. Biochem Biophys Res Commun 1990; 170: 238-42.
29. 2-medialed human platelet responses. Mol Pharmacol 1990; 39: 475-80.
30. Asahi M, Yanagi S, Ohta S, Inazu T, Sakai K, Takeuchi F, Taniguchi T, Yamamura H. Thrombin-induced human platelet aggregation is inhibited by protein-tyrosine kinase inhibitors, ST638 and genistein. FEBS Letts 1992; 309: 10-4.
31. 2. Biochem Biophys Res Comm 1990; 170: 259-63.
32. Lerea KM, Tonks NK, Krebs EG, Fischer EH, Glomset JA. Vanadate and molybdate increase tyrosine phosphorylation in a 50-kilodalton protein and stimulate secretion in electropermeabilised platelets. Biochem 1989; 28: 9286-92.
33. Shattil SJ, Ginsberg MH, Brugge JS. Adhesive signalling in platelets. Curr Opin Cell Biol 1994; 6: 695-704.
34. Clark EA, Shattil SJ, Brugge JS. Regulation of protein tyrosine kinases in platelets. Trends Biochem Sci 1994; 19: 464-9.
35. Clark EA, Brugge JS. Tyrosine phosphorylation in platelets. Potential roles in intracellular signal transduction. Trends Cardiovasc Med 1993; 3: 218-27.
36. Soriano P, Montgomery C, Geske R, Bradley A. Targeted disruption of c-src proto-oncogene leads to osteopetrosis mice. Cell 1991; 64: 693-702.
37. fyn. Cell 1992; 70: 751-763.
38. fyn mutant mice display differential signalling in thymocytes and peripheral T cells. Cell 1992; 70: 741-50.
39. Hibbs ML, Tarlinton DM, Armes J, Grail D, Hodgson G, Maglitto R, Stacker SA, Dunn AR. Multiple defects in the immune system of lyn-deficient mice, culminating in autoimmune disease. Cell 1995; 83: 301-11.
40. Superti-Furga G, Courtneidge SA. Structure-function relationships in src family and related protein tyrosine kinases. Bioessays 1995; 17: 321-30.
41. Pawson T, Schlessinger J. SH2 and SH3 domains. Curr Biol 1993; 3: 434-42.
42. Kaplan KB, Bibbins KB, Swedlow JR, Arnaud M, Morgan DO, Varmus HE. Association of the amino-terminal half of c-src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527. EMBO J 1994; 13: 4745-56.
43. Weng Z, Thomas SM, Rickles RJ, Taylor JA, Brauer AW, Seidel-Dugan C, Michael WM, Dreyfuss G, Brugge JS. Identification of src, fyn, and lyn SH3-binding proteins: implications for a function of SH3 domains. Mol Cell Biol 1994; 14: 4509-21.
44. c-src myristoylation and membrane association and for cell transformation. Mol Cell Biol 1985; 4: 1834-42.
45. c-src. Nature 1991; 349: 172-5.
46. Cooper JA, Howell B. The when and how of Src regulation. Cell 1993; 73: 1051-4.
47. c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets. Mol Cell Biol 1993; 13: 1863-71.
48. src with Triton X-100-resistant cellular structure correlates with morphological transformation. Proc Natl Acad Sci USA 1987; 84: 2312-6.
49. FAK accompanies cell adhesion to the extracellular matrix: a role in cytoskeletal assembly. J Cell Biol 1992; 119: 893-903.
50. c-src protein tyrosine kinase. FEBS Letts 1990; 262: 1-4.
51. src with Triton X-100-insoluble residue in human blood platelets requires platelet aggregation and actin polymerisation. J Biol Chem 1992; 267: 20075-81.
52. c-src to the cytoskeleton during platelet aggregation. EMBO J 1992; 11: 855-61.
53. Kaplan KB, Swedlow JR, Morgan DO, Varmus HE. c-Src enhances the spreading of src -/- fibroblasts on fibronectin by a kinase-independent mechanism. Genes and Development 1995; 9: 1505-17.
54. FAK, a structurally distinctive protein tyrosine kinase associated with focal adhesions. Proc Natl Acad Sci USA 1992; 89: 5192-6.
55. Kornberg L, Earp HS, Parsons JT, Schaller MD, Juliano RL. Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase. J Biol Chem 1992; 267: 23439-42.
56. Guan J, Shalloway D. Regulation of focal adhesion associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation. Nature 1992; 358: 690-2.
57. FAK, to cellular focal adhesions. J Cell Biol 1993; 123: 993-1005.
58. Schaller MD, Parsons JT. Focal adhesion kinase and associated proteins. Curr Opin Cell Biol 1994; 6: 705-10.
59. Schaller MD, Otey CA, Hildebrand Jd, Parsons JT. Focal adhesion kinase and paxillin bind to peptides mimicking β integrin cytoplasmic domains. J Cell Biol 1995; 130: 1181-7.
60. Hildebrand JD, Schaller MD, Parsons JT. Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase. Mol Biol Cell 1995; 6: 637-47.
61. Chen H, Appeddu PA, Parsons JT, Hildebrand JD, Schaller MD, Guan J. Interaction of focal adhesion kinase with cytoskeletal protein talin. J Biol Chem 1995; 270: 16995-9.
62. Miyamoto S, Teramoto H, Coso OA, Gutkind JS, Burbelo PD, Akiyama SK, Yamada KM. Integrin function: Molecular hierarchies of cytoskeletal and signalling molecules. J Cell Biol 1995; 131: 791-805.
63. Calalb MB, Polte TR, Hanks SK. Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for src family kinases. Mol Cell Biol 1995; 15: 954-63.
64. FAK. Mol Cell Biol 1994; 14: 147-55.
65. src. Mol Cell Biol 1994; 14: 1680-8.
66. FAK. Mol Cell Biol 1995; 15: 2819-27.
67. Schlaepfer DD, Hanks SK, Hunter T, van der Geer P. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 1994; 372: 786-91.
68. FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol Cell Biol 1995; 15: 2635-45.
69. Chen H, Guan J. Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA 1994; 91: 10148-52.
70. Bachelot C, Rameh L, Parsons JT, Cantley LC. Association of phosphatidylinositol 3-kinase, via the SH2 domains of p85, with focal adhesion kinase in polyoma middle T-transformed fibroblasts. Biochim Biophys Acta 1996; 1311: 45-52.
71. Parson JT. Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins. Curr Opin Cell Biol 1996; 8: 146-52.
72. FAK) cleavage and regulation by calpain. Biochem J 1996; 318: 41-7.
73. FAK in platelets requires coordinated signalling through integrin and agonist receptors. J Biol Chem 1994; 269: 14738-45.
74. FAK in platelets adherent to fibrinogen. Blood 1996; 87: 152-61.
75. Avraham H, London R, Fu Y, Ota S, Hiregowdara D, Li J, Jiang S, Pasztor LM, White RA, Groopman JE, Avraham S. Identification and characterisation of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain, Blood 1995; 86 (Suppl. 1): 282a.
76. Avraham S, London R, Fu Y, Ota S, Hiregowdara D, Li J, Jiang S, Pasztor LM, White RA, Groopman JE, Avraham H. Identification and characterisation of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain. J Biol Chem 1995; 270: 27742-51.
77. Sasaki H, Nagura K, Ishino M, Tobioka H, Kotani K, Sasaki T. Cloning and characterisation of cell adhesion kinase β, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily. J Biol Chem 1995; 270: 21206-19.
78. Lev S, Moreno H, Martinez R, Canoll P, Peles E, Musacchio JM, Plowman GD, Rudy B, Schlessinger J. Protein tyrosine kinase PYK2 involved in calcium-induced regulation of ion channel and MAP kinase functions. Nature 1995; 376: 737-45.
79. Syk. A B-cell protein tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex. J Biol Chem 1994; 269: 12310-9.
80. + thymic selection in human lacking ZAP-70 kinase. Cell 1994; 76: 947-58.
81. Negishi I, Mooyama N, Nakayama K, Senju S, Hatakeyama S, Zhang Q, Chan AC, Loh DY. Essential role for ZAP-70 in both positive and negative selection of thymocytes. Nature 1995; 376: 435-8.
82. Syk. J Biol Chem 1994; 269: 12310-19.
83. Kolanus W, Romeo C, Seed B. T cell activation by clustered tyrosine kinases. Cell 1993; 74: 171-83.
84. syk by T-cell antigen receptor/CD3 stimulation. Proc Natl Acad Sci USA 1994; 91: 5301-5.
85. Turner M, Mee PJ, Costello PS, Williams O, Price AA, Duddy LP, Furlong MT, Geahlen RL, Tybulewicz VLJ. Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk. Nature 1995; 378: 298-302.
86. Cheng AM, Rowley B, Pao W, Hayday A, Bolen JB, Pawson T. Syk tyrosine kinase required for mouse viability and B-cell development. Nature 1995; 378: 303-6.
87. Shiue L, Zoller MJ, Brugge JS. Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE. J Biol Chem 1995; 270: 10498-502.
88. Chan AC, Desai DM, Weiss A. The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Annu Rev Immunol 1994; 12: 555-92.
89. 2+ mobilisation in platelets. J Biol Chem 1993; 268, 2277-9.
90. Huang MM, Indik Z, Brass LF, Hoxie JA, Schreiber AD, Brugge JS. Activation of FcgRII induces tyrosine phosphorylation of multiple proteins including FcgRII. J Biol Chem 1992; 267: 5467-73.
91. syk. J Biol Chem 1994; 269: 32435-40.
92. syk noncovalently associate with the low affinity Fcg receptor on human platelets through an immunoreceptor tyrosine-based activation motif. J Biol Chem 1996; 271: 10775-81.
93. Yanaga F, Poole A, Asselin J, Blake R, Schieven GL, Clark EA, Watson SP. Syk interacts with tyrosine-phosphorylated proteins in human platelets activated by collagen and cross-linking of the FcgIIa receptor. Biochem J 1995; 311: 471-8.
94. syk) with phosphatidylinositol 3-kinase are early events during platelet activation. Eur J Biochem 1994; 224: 329-33.
95. 3. J Biol Chem 1994; 269: 28859-64.
96. Clark EA, Trikha M, Markland FS, Brugge JS. Structurally distinct disintegrins contortrostatin and multisquamatin differentially regulate platelet tyrosine phosphorylation. J Biol Chem 1994; 269: 21940-3.
97. Wilks AF, Harpur AG. Cytokine signal transduction and the JAK family of protein tyrosine kinases. Bioessays 1994; 16: 313-20.
98. Wilks AF, Harpur AG, Kurban RR, Ralph SJ, Zurcher G, Ziemiecki A. Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase. Mol Cell Biol 1991; 11: 2057-65.
99. Rodriguez-Linares B, Watson SP. Phosphorylation of JAK2 in thrombin-stimulated human platelets. FEBS Letts 1994; 352: 335-8.
100. Ferrel JE, Martin GS. Platelet tyrosine-specific protein phosphorylation is regulated by thrombin. Mol Cell Biol 1988; 8: 3603-10.
101. Pumiglia KM, Feinstein MB. Thrombin and thrombin receptor agonist peptide induce tyrosine phosphorylation and tyrosine kinases in the platelet cytoskeleton. Biochem J 1993; 294: 253-60.
102. Golden A, Brugge JS, Shattil SJ. Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins. J Cell Biol 1990; 111: 3117-27.
103. Fox JEB, Lipfert L, Clark EA, Reynolds CC, Austin CD, Brugge, JS. On the role of the platelet membrane skeleton in mediating signal transduction. J Biol Chem 1993; 268: 25973-84.
104. src substrate, is a filamentous actin-binding protein enriched in the cell cortex. J Cell Biol 1993; 120: 1417-26.
105. Li RY, Gaits F, Ragab A, Ragab-Thomas JMF, Chap H. Tyrosine phosphorylation of an SH2-containing protein tyrosine phosphatase is coupled to platelet thrombin receptor via a pertusis toxin-sensitive heterodimeric G-protein. EMBO J 1995; 14: 2519-26.
106. FAK. J Cell Biol 1993; 122: 473-83.
107. Fox JEB. The platelet cytoskeleton. Thromb Haemost 1993; 70: 884-93.
108. Plopper GE, McNamee HP, Dike LE, Bojanowski K, Ingber DE. Convergence on integrin and growth factor receptor signaling pathways within the focal adhesion complex. Mol Biol Cell 1995; 6: 1349-65
109. Haimovich B, Lipfert L, Brugge JS, Shattil SJ. Tyrosine phosphorylation and cytoskeletal reorganisation in platelets are triggered by interaction of integrin receptors with their immobilised ligands. J Biol Chem 1993; 268: 15868-77.
110. Miyamoto S, Akiyama SK, Yamada KM. Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science 1995; 267: 883-5.
111. Li RY, Gaits F, Ragab A, Ragad-Thomas JMF, Chap H. Translocation of an SH2-containing protein tyrosine phosphatase (SH-PTP1) to the cytoskeleton of thrombin-activated platelets. FEBS Letts 1994; 343: 89-93.
112. Frangioni JV, Oda A, Smith M, Salzman EW, Neel BG. Calpain-catalysed cleavage and subcellular relocation of protein phosphotyrosine phosphatase 1B (PTP-1B) in human platelets. EMBO J 1993; 12: 4843-56.
113. Charbonneau H, Tonks NK, Walsh KA, Fischer EH. The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase. Proc Natl Acad Sci USA 1988; 85: 7182-6.
114. Frangioni JV, Beahm PH, Shifrin V, Jost CA, Neel BG. The non-transmembrane tyrosine phosphatase PTP-1B localises to the endoplasmic reticulum via its 35 amino acid C-terminal sequence. Cell 1992; 68: 545-60.
115. Flint AJ, Gebbink FGB, Franza BR, Hill DE, Tonks NK. Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation. EMBO J 1993; 12: 1937-46.
116. Schievella AR, Paige LA, Johnson KA, Hill DE, Erikson RL. Protein tyrosine phosphatase 1B undergoes mitosis-specific phosphorylation on serine. Cell Growth Differ 1993; 4: 239-46.
117. Shen S, Bastien L, Posner BI, Chretien P. A protein tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases. Nature 1991; 352: 736-9.
118. Plutzky J, Neel BG, Rosenberg RD. Isolation of a src homology 2-containing tyrosine phosphatase. Proc Natl Acad Sci USA 1992; 89: 1123-7.
119. Yi T, Cleveland JL, Ihle JN. Protein tyrosine phosphatase containing SH2 domains: characterisation, preferential expression in haematopoietic cells, and localisation to human chromosome 12 p12-p13. Mol Cell Biol 1992; 12: 836-46.
120. Matthews RJ, Bowne DB, Flores E, Thomas ML. Characterisation of haematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences. Mol Cell Biol 1992; 12: 2396-405.
121. Adachi M, Fischer EH, Ihle J, Imai K, Jirik F, Neel B, Pawson T, Thomas T, Ullrich A, Zhao Z. Mammalian SH2-containing protein tyrosine phosphatases. Cell 1996; 85: 15.
122. Tsui HW, Siminovitch KA, Souza L, Tsui FWL. Motheaten and viable motheaten mice have viable mutations in the haematopoietic cell phosphatase gene. Nature Genetics 1993; 4: 124-9.
123. Schultz LD, Schweitzer PA, Rajan TV, Yi T, Ihle JN, Matthews RJ, Thomas ML, Beier DR. Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene. Cell 1993; 73: 1445-54.
124. Kozlowski M, Mlinaric-Rascan I, Feng GS, Shen R, Pawson T, Siminovitch KA. Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice. J Exp Med 1993; 178: 2157-63.
125. Yi T, Mui A L, Krystal G, Ihle JN. Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis. Mol Cell Biol 1993; 13: 7577-86.
126. Falet H, Ramos-Morales F, Bachelot C, Fischer S, Rendu F. Association of the protein tyrosine phosphatase PTP1C with the protein tyrosine kinase c-src in human platelets. FEBS Letts 1996; 383: 165-9.
127. Zhao Z, Shen SH, Fischer EH. Stimulation by phospholipids of a protein-tyrosine-phosphatase containing two src homology 2 domains. Proc Natl Acad Sci USA 1993; 90: 4251-5.
128. Freeman RM, Plutzky J, Neel BG. Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew. Proc Natl Acad Sci USA 1992; 89: 11239-43.
129. Feng GS, Hui CC, Pawson T. SH2-containing phosphotyrosine phosphatase as target of protein-tyrosine kinases. Science 1993; 259: 1607-11.
130. Vogel W, Lammers R, Huang J, Ullrich A. Activation of phosphotyrosine phosphatase by tyrosine phosphorylation. Science 1993; 259: 1611-4.
131. Adachi M, Sekiya M, Miyachi T, Matsuno K, Hinoda Y, Imai K, Yachi A. Molecular cloning of a novel protein-tyrosine phosphatase SH-PTP3 with sequence similarity to the src-homology region 2. FEBS Letts 1992; 314: 335-9.
132. Ahmad S, Banville D, Zhao Z, Fischer EH, Shen SH. A widely expressed human protein-tyrosine phosphatase containing src homology 2 domains. Proc Natl Acad Sci USA 1993; 90: 2197-201.
133. Lechleider RJ, Freeman RM Jr, Neel BG. Tyrosyl phosphorylation and growth factor receptor association of the human corkscrew homologue, SH-PTP2. J Biol Chem 1993; 268: 13434-8.
134. Lechleider RJ, Sugimoto S, Bennett AM, Kashishian AS, Cooper JA, Shoelson SE, Walsh CT, Neel BG. Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine-1009, on the human platelet-derived growth factor receptor. J Biol Chem 1993; 268: 21478-81.
135. Dechert U, Adam M, Harder KW, Clark-Lewis I, Jirik F. Characterisation of protein tyrosine phosphatase SH-PTP2. Study of phosphopeptide substrates and possible regulatory role of SH2 domains. J Biol Chem 1994; 269: 5602-11.
136. Li W, Nishimura R, Kashishian A, Batzer AG, Kim WJH, Cooper JA, Schlessinger J. A new function for a phosphotyrosine phosphatase-linking GRB2-SOS to a receptor tyrosine kinase. Mol Cell Biol 1994; 14: 509-17.
137. src is an endogenous substrate for calpain in human blood platelets. J Biol Chem 1993; 268: 12603-8.
138. Saido TC, Sorimachi H, Suzuki K. Calpain: new perspectives in molecular diversity and physiological-pathological involvement. FASEB J 1994; 8: 814-22.
139. Fox JEB, Taylor RG, Taffarel M, Boyles JK, Goll DE. Evidence that activation of platelet calpain is induced as a consequence of binding of adhesive ligand to the integrin, glycoprotein IIb-IIIa. J Cell Biol 1993; 120: 1501-7.
140. Fox JEB, Santos G, Zuerbig S, Saido TC. Role of the cytoskeleton in regulating integrin-induced transmembrane signalling. Thromb Haemost 1995; 73: 987 (Abstr).
141. Fox JEB, Austin CD, Reynolds CC, Steffen PK. Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets. J Biol Chem 1991; 266, 13289-95.
142. Fox JEB, Austin CD, Boyles JK, Steffen PK. Role of membrane skeleton in preventing the shedding of procoagulant-rich microvesicles from the platelet plasma membrane. J Cell Biol 1990; 111: 483-93.
143. Fox JEB, Reynolds CC, Austin CD. The role of calpain in stimulus-response coupling: evidence that calpain mediates agonist-induced expression of procoagulant activity in platelets. Blood 1990; 76: 2510-9.
144. Gemmell CH, Sefton MV, Yeo EL. Platelet-derived microparticle formation involves glycoprotein IIb-IIIa. J Biol Chem 1993; 268: 14586-9.
145. Basse F, Gaffet P, Bienvenue A. Correlation between inhibition of cytoskeleton proteins and anti-vesiculation effect of calpeptin during A23187-induced activation of human platelets: are vesicles shed by filopod fragmentation? Biochim Biophys Acta 1994; 1190: 217-24.
146. Yano Y, Shiba E, Kambayashi J, Sakon M, Kawasaki T, Fujitani K, Kang J, Mori T. The effect of calpeptin (a calpain specific inhibitor) on agonist induced microparticle formation from the platelet plasma membrane. Thromb Res 1993; 71: 385-96.
147. Zwaal RF, Comfurius P, Bevers EM. Platelet procoagulant activity and microvesicle formation. Its putative role in hemostasis and thrombosis. Biochim Biophys Acta 1992; 1180: 1-8.
148. Beckerle MC, Burridge K, DeMartino GN, Croall DE. Colocalisation of calcium-dependent protease II and one of its substrates at sites of cell adhesion. Cell 1987; 51: 569-77.
149. Ariyoshi H, Oda A, Salzman EW. Participation of calpain in protein-tyrosine phosphorylation and dephosphorylation in human blood platelets. Arterioscl Thromb Vasc Biol 1995; 15: 511-4.
150. Douglas CG, Holub B. Effect of Genistein, a tyrosine kinase inhibitor, on U46619-induced phosphoinositide phosphorylation in human platelets. Biochem Biophys Res Comm 1990; 238-42.
151. 3 (platelet glycoprotein IIb/IIIa) and the cellular retraction of fibrin polymers. J Biol Chem 1994; 269: 32479-87.