메뉴 건너뛰기




Volumn 184, Issue 6, 2001, Pages 1211-1217

Genetic susceptibility to preeclampsia: Roles of cytosine-to-thymine substitution at nucleotide 677 of the gene for methylenetetrahydrofolate reductase, 68-base pair insertion at nucleotide 844 of the gene for cystathionine β-synthase, and factor V Leiden mutation

Author keywords

Cystathione synthase; Factor V Leiden; HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome; Methylenetetrahydrofolate reductase; Preeclampsia

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); BLOOD CLOTTING FACTOR 5 LEIDEN; CYSTATHIONINE BETA SYNTHASE;

EID: 0035340294     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1067/mob.2001.110411     Document Type: Article
Times cited : (87)

References (25)
  • 1
    • 0033041759 scopus 로고    scopus 로고
    • New insights into the genetics of preeclampsia
    • Morgan T, Ward K. New insights into the genetics of preeclampsia. Semin Perinatol 1999;23:14-23.
    • (1999) Semin Perinatol , vol.23 , pp. 14-23
    • Morgan, T.1    Ward, K.2
  • 2
    • 0029999583 scopus 로고    scopus 로고
    • The factor V Leiden mutation may predispose women to severe preeclampsia
    • Dizon-Townson DS, Nelson LM, Easton K, Ward K. The factor V Leiden mutation may predispose women to severe preeclampsia. Am J Obstet Gynecol 1996;175:902-5.
    • (1996) Am J Obstet Gynecol , vol.175 , pp. 902-905
    • Dizon-Townson, D.S.1    Nelson, L.M.2    Easton, K.3    Ward, K.4
  • 4
    • 0032978344 scopus 로고    scopus 로고
    • Factor V Leiden and thermolabile methylene tetrahydrofolate reductase gene variants in an East Anglian preeclampsia cohort
    • O'Shaughnessy KM, Fu B, Ferraro F, Lewis I, Downing S, Morris NH. Factor V Leiden and thermolabile methylene tetrahydrofolate reductase gene variants in an East Anglian preeclampsia cohort. Hypertension 1999;33:1338-41.
    • (1999) Hypertension , vol.33 , pp. 1338-1341
    • O'Shaughnessy, K.M.1    Fu, B.2    Ferraro, F.3    Lewis, I.4    Downing, S.5    Morris, N.H.6
  • 5
    • 0029939676 scopus 로고    scopus 로고
    • Homocysteine and vascular disease
    • McCully KS. Homocysteine and vascular disease. Nat Med 1996;2:386-9.
    • (1996) Nat Med , vol.2 , pp. 386-389
    • McCully, K.S.1
  • 9
    • 0029655724 scopus 로고    scopus 로고
    • Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease
    • Kluijtmans LA, van den Heuvel LP, Boers GH, Frosst P, Stevens EM, van Oost BA, et al. Molecular genetic analysis in mild hyperhomocysteinemia: A common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am J Hum Genet 1996;58:35-41.
    • (1996) Am J Hum Genet , vol.58 , pp. 35-41
    • Kluijtmans, L.A.1    Van Den Heuvel, L.P.2    Boers, G.H.3    Frosst, P.4    Stevens, E.M.5    Van Oost, B.A.6
  • 10
    • 0029068922 scopus 로고
    • The molecular basis of homocystinuria due to cystathionine beta-synthase deficiency in Italian families, and report of four novel mutations
    • Sebastio G, Sperandeo MP, Panico M, de Franchis R, Kraus JP, Andria G. The molecular basis of homocystinuria due to cystathionine beta-synthase deficiency in Italian families, and report of four novel mutations. Am J Hum Genet 1995;56:1324-33.
    • (1995) Am J Hum Genet , vol.56 , pp. 1324-1333
    • Sebastio, G.1    Sperandeo, M.P.2    Panico, M.3    De Franchis, R.4    Kraus, J.P.5    Andria, G.6
  • 11
    • 0029829735 scopus 로고    scopus 로고
    • High prevalence of a mutation in the cystathionine β-synthase gene
    • Tsai MY, Bignell M, Schwichtenberg K, Hanson NQ. High prevalence of a mutation in the cystathionine β-synthase gene. Am J Hum Genet 1996;59:1262-7.
    • (1996) Am J Hum Genet , vol.59 , pp. 1262-1267
    • Tsai, M.Y.1    Bignell, M.2    Schwichtenberg, K.3    Hanson, N.Q.4
  • 12
  • 13
    • 0029153954 scopus 로고
    • The polymerase chain reaction with sequence specific primers for the detection of the factor V mutation associated with activated protein C resistance
    • Kirschbaum N, Foster P. The polymerase chain reaction with sequence specific primers for the detection of the factor V mutation associated with activated protein C resistance. Thromb Haemost 1995;74:874-8.
    • (1995) Thromb Haemost , vol.74 , pp. 874-878
    • Kirschbaum, N.1    Foster, P.2
  • 14
    • 0028048799 scopus 로고
    • Inherited resistance to activated protein C, a major cause of venous thrombosis, is due to a mutation in the factor V gene
    • Dahlbäck B. Inherited resistance to activated protein C, a major cause of venous thrombosis, is due to a mutation in the factor V gene. Haemostasis 1994;24:139-51.
    • (1994) Haemostasis , vol.24 , pp. 139-151
    • Dahlbäck, B.1
  • 15
    • 0032893230 scopus 로고    scopus 로고
    • Analysis of select folate pathway genes, PAX3, and human T in a Midwestern neural tube defect population
    • Trembath D, Sherbondy AL, Vandyke DC, Shaw M, Todoroff K, Lammer EJ, Analysis of select folate pathway genes, PAX3, and human T in a Midwestern neural tube defect population. Teratology 1999;59:331-41.
    • (1999) Teratology , vol.59 , pp. 331-341
    • Trembath, D.1    Sherbondy, A.L.2    Vandyke, D.C.3    Shaw, M.4    Todoroff, K.5    Lammer, E.J.6
  • 16
    • 0033049262 scopus 로고    scopus 로고
    • Plasma homocysteine levels elevated and inversely related to insulin sensitivity in preeclampsia
    • Laivuori H, Kaaja R, Turpeinen U, Viinikka L, Ylikorkala O. Plasma homocysteine levels elevated and inversely related to insulin sensitivity in preeclampsia. Obstet Gynecol 1999;93:489-93.
    • (1999) Obstet Gynecol , vol.93 , pp. 489-493
    • Laivuori, H.1    Kaaja, R.2    Turpeinen, U.3    Viinikka, L.4    Ylikorkala, O.5
  • 17
    • 0032428626 scopus 로고    scopus 로고
    • Plasma homocysteine concentration is increased in preeclampsia and is associated with evidence of endothelial activation
    • Powers RW, Evans RW, Majors AK, Ojimba JI, Ness RB, Crombleholme WR, et al. Plasma homocysteine concentration is increased in preeclampsia and is associated with evidence of endothelial activation. Am J Obstet Gynecol 1998;179:1605-11.
    • (1998) Am J Obstet Gynecol , vol.179 , pp. 1605-1611
    • Powers, R.W.1    Evans, R.W.2    Majors, A.K.3    Ojimba, J.I.4    Ness, R.B.5    Crombleholme, W.R.6
  • 22
    • 0031863219 scopus 로고    scopus 로고
    • Changes of resistance to activated protein C in the course of pregnancy and prevalence of factor V mutation
    • Mimuro S, Lahoud R, Beutler L, Trudinger B. Changes of resistance to activated protein C in the course of pregnancy and prevalence of factor V mutation. Aust N Z J Obstet Gynaecol 1999;38:200-4.
    • (1999) Aust N Z J Obstet Gynaecol , vol.38 , pp. 200-204
    • Mimuro, S.1    Lahoud, R.2    Beutler, L.3    Trudinger, B.4
  • 23
    • 2642617790 scopus 로고    scopus 로고
    • Detection of factor V Leiden mutation in severe preeclamptic Hungarian women
    • Nagy B, Toth T, Rigo J, Karadi I, Romics L, Papp Z. Detection of factor V Leiden mutation in severe preeclamptic Hungarian women. Clin Genet 1998;53:479-81.
    • (1998) Clin Genet , vol.53 , pp. 479-481
    • Nagy, B.1    Toth, T.2    Rigo, J.3    Karadi, I.4    Romics, L.5    Papp, Z.6
  • 24
    • 0033531184 scopus 로고    scopus 로고
    • Increased frequency of genetic thrombophilia in women with complications of pregnancy
    • published erratum appears in N Engl J Med 1999;341:384
    • Kupferminc MJ, Eldor A, Steinman N, Many A, Bar-Am A, Jaffa A, et al. Increased frequency of genetic thrombophilia in women with complications of pregnancy [published erratum appears in N Engl J Med 1999;341:384]. N Engl J Med 1999;340:9-13.
    • (1999) N Engl J Med , vol.340 , pp. 9-13
    • Kupferminc, M.J.1    Eldor, A.2    Steinman, N.3    Many, A.4    Bar-Am, A.5    Jaffa, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.