GIF inhibits Th effector generation by acting on antigen-presenting B cells

Journal of Immunology

Volumn 166, Issue 7, 2001, Pages 4473-4480

  Sugie, K ^a   Huang, J ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD4 ANTIGEN; CYTOKINE; GAMMA INTERFERON; GLYCOSYLATION INHIBITING FACTOR; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G1; INTERLEUKIN 2; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; LYSOZYME; PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY RESPONSE; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CELL INTERACTION; CELL SECRETION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE;

EID: 0035313571     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.7.4473     Document Type: Article

References (33)

1. Functional diversity of helper T lymphocytes
2. The Th1/Th2 paradigm
3. - cells and interferon γ
4. Anergy and cytokine-mediated suppression as distinct superantigen-induced tolerance mechanisms in vivo
5. Immunosuppressive effects of glycosylation inhibiting factor on the IgE and IgG antibody response
6. Molecular cloning and functional expression of a cDNA encoding glycosylation-inhibiting factor
7. The crystal structure of human glycosylation-inhibiting factor is a trimeric barrel with three 6-stranded ß-sheets
8. Immunosuppressive activities of recombinant glycosylation-inhibiting factor mutants
9. Posttranslational modification of the glycosylation inhibiting factor (GIF) gene product generates bioactive GIF
10. High-affinity binding of bioactive glycosylation-inhibiting factor to anti-gen-primed T cells and natural killer cells
11. Regulation of IgE synthesis
12. Target cells for an immunosuppressive cytokine, glycosylation-inhibiting factor
13. T cell-dependent B cell activation
14. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
15. + T cells to produce IL-4
16. Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the JH locus
17. Antigen-primed T cells from B cell-deficient JHD mice fail to provide B cell help
18. Antigen-specific interaction between T and B cells
19. 10 thymocytes in vivo
20. Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses
21. + T cells in vitro: Characteristics and antigen-presenting cell requirements
22. Processing of switch transcripts is required for targeting of antibody class switch recombination
23. TCR antagonist peptides induce formation of APC-T cell conjugates and activate a Rac signaling pathway
24. Inaugural article: T-cell receptor antagonists induce vav phosphorylation by selective activation of fyn kinase
25. Antigen presentation by splenic B cells: Resting B cells are ineffective, whereas activated B cells are effective accessory cells for T cell responses
26. + T lymphocytes from TCR transgenic mice
27. Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals
28. CD28/B7 system of T cell costimulation
29. Accessory molecule and costimulation requirements for CD4 T cell response
30. T cell co-stimulatory molecules other than CD28
31. + T cells
32. The HLA-A*0201-restricted H-Y antigen contains a posttranslationally modified cysteine that significantly affects T cell recognition
33. Modification of cysteine residues in vitro and in vivo affects the immunogenicity and antigenicity of major histocompatibility complex class I-restricted viral determinants