Monitoring the structure of Escherichia coli RNase P RNA in the presence of various divalent metal ions

Nucleic Acids Research

Volumn 29, Issue 7, 2001, Pages 1426-1432

  Brannvall M ^a   Mikkelsen, N E ^a   Kirsebom, L A ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL RNA; BARIUM ION; CADMIUM; CALCIUM ION; COBALT; DIVALENT CATION; LEAD; MAGNESIUM ION; MANGANESE; METAL ION; METHENAMINE; PHENYLALANINE TRANSFER RNA; RIBONUCLEASE P; SPERMIDINE; STRONTIUM;

ARTICLE; BINDING AFFINITY; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; ESCHERICHIA COLI; INFORMATION; METAL BINDING; MONITORING; NONHUMAN; PRIORITY JOURNAL; RNA BINDING; RNA STRUCTURE; YEAST;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0035312611     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.7.1426     Document Type: Article

References (43)

1. The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
2. Site-specific cleavage by metal ion cofactors and inhibitors of M1 RNA, the catalytic subunit of RNase P from Escherichia coli
3. Influence of metal ions on the ribonuclease P reaction
4. Multiple magnesium ions in the ribonuclease P reaction mechanism
5. Cleavage site selection by M1 RNA, the catalytic subunit of Escherichia coli RNase P, is influenced by pH
6. Different cleavage sites are aligned differently in the active site of M1 RNA, the catalytic subunit of Escherichia coli RNase P
7. Residues in Escherichia coli RNase P RNA important for cleavage site selection and divalent metal ion binding
8. 2+-ribozyme by a single Rp-phosphorothioate modification in the precursor tRNA at the RNase P cleavage site
9. 2+ coordinated to the pro-Rp oxygen of the scissile bond
10. Manganese ions induce miscleavage in the Escherichia coli RNase P RNA-catalyzed reaction
11. Oligoribonucleotide synthesis using T7 RNA polymerase and DNA templates
12. Protein-RNA interactions in the RNase P holoenzyme from Escherichia coli
13. Lead-ion-induced cleavage of RNase P RNA
14. Phe mutants
15. A novel tertiary interaction in M1 RNA, the catalytic subunit of Escherichia coli RNase P
16. Characterization of the Borrelia burgdorferi RNase P RNA gene reveals a novel tertiary interaction
17. Lead-catalyzed cleavage of ribonuclease P RNA as a probe for integrity of tertiary structure
18. Kinetics and thermodynamics of the RNase P RNA cleavage reaction: Analysis of tRNA 3′-end variants
19. Domain structure of the ribozyme from eubacterial ribonuclease P
20. Metal ion requirements and other aspects of the reaction catalyzed by M1 RNA, the RNA subunit of ribonuclease P from Escherichia coli
21. Slow folding kinetics of RNase P RNA
22. The P15-loop of Escherichia coli RNase P RNA is an autonomous divalent metal ion binding domain
23. Intermediates and kinetic traps in the folding of a large ribozyme revealed by circular dichroism and UV absorbance spectroscopies and catalytic activity
24. On the role of magnesium ions in RNA stability
25. Inhibition of RNase P RNA cleavage by aminoglycosides
26. The role of metal ions in RNA biochemistry
27. Important 2′ hydroxyl groups in model substrates for M1 RNA, the catalytic RNA subunit of RNase P from Escherichia coli
28. Pathway of activation by magnesium ions of substrates for the catalytic RNA subunit of RNase P from Escherichia coli
29. Folding of circularly permuted transfer RNAs
30. Lead cleavage sites in the core structure of group I intron-RNA
31. The environment of two metal ions surrounding the splice site of a group I intron
32. Phe
33. Electrophoresis of DNA. II. Specific interactions of univalent and divalent cations with DNA
34. Ion dependence of the Bacillus subtilis RNase P reaction
35. Manganese as a replacement for magnesium and zinc: Functional comparison of the divalent metal ions
36. A crystallographic study of metal-binding to yeast phenylalanine transfer RNA
37. Metal ion requirements for sequence-specific endoribonuclease activity of the Tetrahymena ribozyme
38. Metal ion dependence of active-site structure of the Tetrahymena ribozyme revealed by site-specific photo-cross-linking
39. Visuzalizing the higher order folding of a catalytic RNA molecule
40. Phylogenetic comparative mutational analysis of the base-pairing between RNase P RNA and its substrate
41. Structure and evolution of ribonuclease P RNA in gram-positive bacteria