Transcriptionally active HERV-K genes: Identification, isolation, and chromosomal mapping

Genomics

Volumn 72, Issue 2, 2001, Pages 137-144

  Sugimoto, Jun ^a   Matsuura, Nobuo ^b   Kinjo, Yoshino ^a   Takasu, Nobuyuki ^a   Oda, Takaya ^c   Jinno, Yoshihiro ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

^b KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE;

ARTICLE; CHROMOSOME MAP; GENE ISOLATION; GENETIC ANALYSIS; GENETIC REGULATION; HUMAN; HUMAN CELL; MESSENGER RNA SYNTHESIS; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; PRIORITY JOURNAL; PROMOTER REGION; RETROPOSON; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TERATOCARCINOMA; TRANSCRIPTION REGULATION;

EID: 0035280901     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.2001.6473     Document Type: Article

References (38)

1. IDDM patients neither show humoral reactivities against endogenous retroviral envelope protein nor do they differ in retroviral mRNA expression from healthy relatives or normal individuals
2. Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans
3. Comparative genetics of type 1 diabetes and autoimmune disease: Common loci, common pathways?
4. Structural organization of unique retrovirus-like particles budding from human teratocarcinoma cell lines
5. New cosmid vectors developed for eukaryotic DNA cloning
6. Germ cell expression of an isolated human endogenous retroviral long terminal repeat of the HERV-K/HTDV family in transgenic mice
7. A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus
8. A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes
9. New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study
10. Solitary HERV-K LTRs possess bi-directional promoter activity and contain a negative regulatory element in the U5 region
11. The presence or absence of a retroviral long terminal repeat influences the genetic risk for type 1 diabetes conferred by human leukocyte antigen DQ haplotypes
12. Cell-specific expression of the rat insulin gene: Evidence for role of two distinct 5′ flanking elements
13. A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families
14. Isolation and localization of an IDDMK,2-22-related human endogenous retroviral gene, and identification of a CA repeat marker at its locus
15. No evidence for association between IDDMK(1,2)22, a novel isolated retrovirus, and IDDM
16. Mosaic and polymorphic imprinting of the WT1 gene in humans
17. Establishment of functional imprinting of the H19 gene in human developing placentae
18. Mobile elements and disease
19. Quantitation of gene expression by real-time PCR disproves a "retroviral hypothesis" for childhood-onset diabetes mellitus
20. HERV-K10s and immune-mediated (type 1) diabetes
21. Functional analysis of the env open reading frame in human endogenous retrovirus IDDMK(1,2)22 encoding superantigen activity
22. Differences in HERV-K LTR insertions in orthologous loci of humans and great apes
23. The viruses in all of us: Characteristics and biological significance of human endogenous retrovirus sequences
24. Development of insulin-dependent diabetes mellitus does not depend on specific expression of the human endogenous retrovirus HERV-K
25. An almost-intact human endogenous retrovirus K on human chromosome 7
26. Human-specific integrations of the HERV-K endogenous retrovirus family
27. A search for type 1 diabetes susceptibility genes in families from the United Kingdom
28. Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis
29. Retrotransposal integration of mobile genetic elements in human diseases
30. Epigenetic inheritance at the agouti locus in the mouse
31. The IDDMK(1,2)22 retrovirus is not detectable in either mRNA or genomic DNA from patients with type 1 diabetes
32. Retroviral superantigens and type 1 diabetes mellitus
33. huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions
34. Nucleotide sequence of human endogenous retrovirus genome related to the mouse mammary tumor virus genome
35. Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis
36. Genetic analysis of type 1 diabetes using whole genome approaches
37. Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K
38. Transcription of IAP endogenous retroviruses is constrained by cytosine methylation