Innovative treatment programs against cancer. I. Ras oncoprotein as a molecular target

Biochemical Pharmacology

Volumn 56, Issue 11, 1998, Pages 1411-1426

  Waddick, K G ^a   Uckun, F M ^a  

^a PARKER HUGHES INSTITUTE   (United States)

Author keywords

Apoptosis; Cancer; Molecular target; Ras; Rational drug design; Signal transduction

Indexed keywords

2 [[2 [[2 [(2 AMINO 3 MERCAPTOPROPYL)AMINO] 3 METHYLPENTYL]OXY] 1 OXO 3 PHENYLPROPYL]AMINO] 4 (METHYLSULFONYL)BUTANOIC ACID ISOPROPYL ESTER; 6 FORMYLAMINO 12,13 DIHYDRO 1,11 DIHYDROXY 5H INDOLO[2,3 A][PYRROLO[3,4 C]CARBAZOLE 5,7(6H) DIONE 13 GLUCOSIDE; ANDRASTATIN D; ANTHRAQUINONE; ANTINEOPLASTIC AGENT; BMS 186511; BUTHIONINE SULFOXIMINE; CHAETOMELLIC ACID; DOXORUBICIN; EMODIN; GENISTEIN; GGTI 298; GROWTH FACTOR; LIMONENE; LIPID; MANUMYCIN; MEVALONIC ACID; N (8 AMINO 2 BENZYL 5 ISOPROPYL 9 MERCAPTO 3,6 NONADIENOYL)METHIONINE; N (8 AMINO 2 BENZYL 5 ISOPROPYL 9 MERCAPTO 3,6 NONADIENOYL)METHIONINE METHYL ESTER; N [2 [2 (2 AMINO 3 MERCAPTOPROPYLAMINO) 3 METHYLPENTYLOXY] 3 PHENYLPROPIONYL]METHIONINE SULFONE METHYL ESTER; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE; PEPTICINNAMIN E; PROTEIN FARNESYLTRANSFERASE INHIBITOR; RAS PROTEIN; STATINE DERIVATIVE; TIAZOFURIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALINOMYCIN;

CANCER CHEMOTHERAPY; CANCER GROWTH; CANCER RADIOTHERAPY; GENE MUTATION; HUMAN; LIPOGENESIS; MITOGENESIS; NONHUMAN; ONCOGENE RAS; PRENYLATION; PRIORITY JOURNAL; REVIEW; SENSITIZATION;

EID: 0031793978     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00211-1     Document Type: Article

References (118)