Age-related regional difference of interleukin-1 expression in rat brain after lipopolysaccharide treatment

Journal of Korean Medical Science

Volumn 16, Issue 1, 2001, Pages 103-107

  Huh, Gi Yeong ^a   Roh, Mee Sook ^a   Bae, Hae Rahn ^a  

^a Dong A University   (South Korea)

Author keywords

Aging; Brain; Immunohistochemistry; Interleukin 1; Lipopolysaccharides; Rats

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; LIPOPOLYSACCHARIDE;

AGE; ANIMAL; ARTICLE; BRAIN LEVEL; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IMMUNOHISTOCHEMISTRY; MALE; RAT; SPRAGUE DAWLEY RAT;

AGE FACTORS; ANIMALS; BRAIN CHEMISTRY; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, INTERLEUKIN-1;

EID: 0035261342     PISSN: 10118934     EISSN: None     Source Type: Journal    
DOI: 10.3346/jkms.2001.16.1.103     Document Type: Article

References (20)

1. Rink L, Cakman I, Kirchner H. Altered cytokine production in the elderly. Mech Ageing Dev 1998; 102: 199-209.
2. Catania A, Airaghi L, Motta P, Manfredi MG, Annoni G, Pettenati C, Brambilla F, Lipton JM. Cytokine antagonists in aged subjects and their relation with cellular immunity. J Gerontol A Biol Sci Med Sci 1997; 52: B93-7.
3. Fagiolo U, Cossarizza A, Santacaterina S, Ortolani C, Monti D, Paganelli R, Franceschi C. Increased cytokine production by peripheral blood mononuclear cells from healthy elderly people. Ann N Y Acad Sci 1992; 663: 490-3.
4. Foster KD, Conn CA, Kluger MJ. Fever, tumor necrosis factor, and interleukin-6 in young, mature, and aged Fischer 344 rats. Am J Physiol 1992; 262: R211-5.
5. Riancho JA, Zarrabeitia MT, Amado JA, Olmos JM, Gonzalez-Marcias J. Age-related differences in cytokine secretion. Gerontology 1994; 40: 8-12.
6. Roubenoff R, Harris TB, Abad LW, Wilson PW, Dallal GE, Dinarello CA. Monocyte cytokine production in an elderly population: effect of age and inflammation. J Gerontol A Biol Sci Med Sci 1998; 53: M20-6.
7. Dayan M, Segal R, Globerson A, Habut B, Shearer GM, Mozes E. Effect of aging on cytokine production in normal and experimental systemic lupus erythematosus-afflicted mice. Exp Gerontol 2000; 35: 225-36.
8. Terrazzino S, Perego C, De Luigi A, De Simoni MG. Interleukin-6, tumor necrosis factor and corticosterone induction by central lipopolysaccharide in aged rats. Life Sci 1997; 61: 695-701.
9. Norman DC, Yamamura RH, Yoshikawa TT. Fever response in old and young mice after injection of interleukin 1. J Gerontol A Biol Sci Med Sci 1988; 43: M80-5.
10. Rothwell N, Allan S, Toulmond S. Cytokines and the brain: the role of interleukin 1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications. J Clin Invest 1997; 100: 2648-52.
11. Blatteis CM, Sehic E. Fever: how many circulating pyrogens signal the brain? New Physiol Sci 1997; 12: 1-9.
12. Kluger MJ. Fever revisited. Pediatrics 1992; 90: 846-50.
13. Luheshi G, Rothwell N. Cytokines and fever. Int Arch Allergy Immunol 1996; 109: 301-7.
14. van Dam AM, Poole S, Schultzberg M, Zavala F, Tilders FJ. Effects of peripheral administration of LPS on the expression of immunoreactive interleukin-1α, β, and receptor antagonist in rat brain. Ann N Y Acad Sci 1998; 840: 128-38.
15. Sims JE, Giri JG, Dower SK. The two interleukin-1 receptors play different roles in IL-1 actions. Clin Immunol Immunopathol 1994; 72: 9-14.
16. Ilyn SE, Gayle D, Flynn MC, Plata-Salaman CR. Interleukin-1β system (ligand, receptor type 1, receptor accessory protein and receptor antagonist), TNF-α, TGF-β1 and neuropeptide Y mRNAs in specific brain regions during bacterial LPS-induced anorexia. Brain Res Bull 1998; 45: 507-15.
17. Gayle D, Ilyin SE, Romanovitch AE, Peloso E, Satinoff E, Plata-Salaman CR. Basal and IL-1β-stimulated cytokine and neuropeptide mRNA expression in the brain regions of young and old Long-Evans rats. Brain Res Mol Brain Res 1999; 70: 92-100.
18. Ericsson A, Liu C, Hart RP, Sawchenko PE. Type 1 interleukin-1 receptor in the rat brain: distribution, regulation, and relationshp to sites of IL-1-induced cellular activation. J Comp Neurol 1995; 361: 681-98.
19. Plata-Salaman CR, Peloso E, Satinoff E. Interleukin-1β-induced fever in young and old Long-Evans rats. Am J Physiol 1998; 275(5 Pt 2): R1633-8.
20. McCluskey LP, Lampson LA. Local neurochemicals and site-specific immune regulation in the CNS. J Neuropathol Exp Neurol 2000; 59: 177-87.