Racial differences and the genetics of hypertension

Current Hypertension Reports

Volumn 3, Issue 1, 2001, Pages 19-24

  Cooper, Richard S ^a   Zhu, Xiaofeng ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAUCASIAN; ETHNOLOGY; GENETIC VARIABILITY; GENETICS; GENOME; HUMAN; HYPERTENSION; NEGRO; REVIEW;

AFRICAN CONTINENTAL ANCESTRY GROUP; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENOME, HUMAN; HUMANS; HYPERTENSION; VARIATION (GENETICS);

EID: 0035258812     PISSN: 15226417     EISSN: 15343111     Source Type: Journal    
DOI: 10.1007/s11906-001-0073-z     Document Type: Article

References (29)

1. Cooper RS, Rotimi C: Hypertension in populations of West African origin. Is there a genetic predisposition? Am J Hypertens 1994, 12: 215-227.
2. Geller DS, Farhi A, Pinkerton N, et al.: Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy. Science 2000, 289: 119-123.
3. Warnock DG: Liddle syndrome: an autosomal dominant form of human hypertension. Kidney Int 1998, 53: 18-24.
4. Lifton RP: Molecular genetics of blood pressure regulation. Science 1996, 272: 676-680.
5. Agerholm-Larsen B, Nordestgaard BH, Tyhjaerg-Hansen A: ACE gene polymorphism in cardiovascular disease: meta-analyses of small and large studies in whites. Arterioscler Thromb Vasc Biol 2000, 2: 484-492.
6. Zhu X, McKenzie C, Forrester T, et al.: Localization of a small genomic region associated with elevated ACE. Am J Hum Genetics 2000, 67: 1144-1153.
7. Keavney B, McKenzie C, Parish S, et al.: Large-scale test of hypothesized associations between the angiotensinconverting enzyme insertion/deletion polymorphism and myocardial infarction in about 5000 cases and 6000 controls. International Studies of Infarct Survival (ISIS) Collaborators. Lancet 2000, 355: 434-442.
8. Rotimi C, Cooper R, Ogunbiyi O, et al.: Hypertension, serum angiotensinogen and molecular variants of the angiotensinogen gene among Nigerians. Circulation 1997, 95: 2348-2350.
9. Province MA, Boerwinkle E, Chakravarti A, et al.: Lack of association of the angiotensinogen-6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program. J Hypertens 2000, 18: 867-875.
10. Williams SM, Addy JH, Phillips JA, et al.: Combinations of variations in multiple genes are associated with hypertension. Hypertension 2000, 36: 2-6.
11. Dong Y, Zhu H, Sagnella GA, et al.: Association between the C825T polymorphism of the G protein beta3-subunit gene and hypertension in blacks. Hypertension 1999, 34: 1193-1196.
12. Schork NJ, Chakravarti A, Theil B, et al.: Lack of association between a bi-allelic polymorphism in the adducin gene and blood pressure in Caucasians and African Americans. Am J Hypertens 2000, 13: 693-698.
13. Ranade K, Hsiung AC, Wu KD, et al.: Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populations. Am J Hypertens 2000, 13: 704-709.
14. Larson N, Hutchinson R, Boerwinkle E: Lack of association of three functional gene variants with hypertension in African Americans. Hypertension 2000, 6: 12970-12300.
15. Risch N: Searching for the genetic determinants in a new millennium. Nature 2000, 405: 847-856.
16. Krushkal J, Ferrell R, Mockrin S, et al.: Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings. Circulation 1999, 99: 1407-1410.
17. Xu X, Yang J, Rogus J, et al.: Mapping of a blood pressure quantitative trait locus to chromosome 15q in a Chinese population. Hum Mol Genet 1999, 8: 2551-2555.
18. Bray MS, Krushkal J, Li L, et al.: Positional genomic analysis identifies the beta2-adrenergic receptor gene as a susceptibility locus for human hypertension. Circulation 2000, 101: 2877-2822.
19. Kotanko P, Binder A, Tasker J, et al.: Esssential hypertension in African Caribbean associates with a variant of the beta2 adrenoreceptor. Hypertension 1999, 4: 773-776.
20. Halushka M, Fan J-B, Bentley K, et al.: Patterns of singlenucleotide polymorphisms in candidate genes for blood pressure homeostasis. Nat Genet 1999, 22: 239-247.
21. Fischer G, James SA, Roberts IN, et al.: Chromosomal evolution in Saccharomyces. Nature 2000, 405: 451-454.
22. Zhu X, Cooper R, Adeyemo A, et al.: Linkage and association analysis of angiotensin I-converting enzyme (ACE) gene polymorphisms with ACE activity and blood pressure. Circulation 2000, submitted.
23. Cargill M, Altshuler D, Ireland J, et al.: Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nature Genet 1999, 22: 231-238.
24. The FBPP Investigators. The Family Blood Pressure Program (FBPP): design and objectives. Am J Hypertens 2000, in press.
25. Relethford JH: Genetics of modern human origins and diversity. Annu Rev Anthropol 1998, 27: 1-23.
26. Kaufman JS, Cooper RS: Considerations for use of racial/ethnic classification in etiologic research. Am J Epidemiol 2000, in press.
27. Cooper RS: Health and the social status of blacks in the United States. Ann Epidemiol 1993, 3: 137-144.
28. Cooper RS, Rotimi CN, Ward R: The puzzle of hypertension in African Americans. Sci American. 1999, 280: 56-63.
29. Darwin C: The Descent of Man. Princeton, NJ: Princeton University Press; 1981.