Systemic deficits in transporter for antigen presentation (TAP)-1 or proteasome subunit LMP2 have little or no effect on tumor incidence

International Journal of Cancer

Volumn 91, Issue 3, 2001, Pages 366-372

  Johnsen, Alyssa K ^a   France, John ^b   Nagy, Nancy ^b   Askew, David ^b   Abdul Karim, Fadi W ^a   Gerson, Stanton L ^b   Sy, Man Sun ^b   Harding, Clifford V ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Antigen presentation; Antigen processing; Major histocompatibility complex; Transporter for antigen presentation 1; Tumor immunity

Indexed keywords

CARRIER PROTEIN; PROTEASOME; PROTEIN P53; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; TRANSPORTER FOR ANTIGEN PRESENTATION; UNCLASSIFIED DRUG;

ANGIOSARCOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ARTICLE; CANCER INCIDENCE; CANCER PREVENTION; CARCINOGENESIS; HUMAN; IMMUNOPATHOGENESIS; KNOCKOUT MOUSE; LYMPHOMA; MAJOR HISTOCOMPATIBILITY COMPLEX; MALIGNANT FIBROUS HISTIOCYTOMA; MORTALITY; MOUSE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SARCOMA; T LYMPHOCYTE; TUMOR IMMUNITY;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CROSSES, GENETIC; CYSTEINE ENDOPEPTIDASES; FEMALE; GENE DELETION; GENES, P53; IMMUNITY, CELLULAR; LYMPHOMA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; PROTEINS; SARCOMA; SURVIVAL ANALYSIS; T-LYMPHOCYTES;

EID: 0035254934     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0215(200002)9999:9999<::AID-IJC1056>3.0.CO;2-K     Document Type: Article

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15. + proteasomes are required for the presentation of specific antigens to cytotoxic T lymphocytes
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36. + T cells
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