메뉴 건너뛰기




Volumn 52, Issue 3, 2001, Pages 273-288

Imaging molecular structure and physiological function of gap junctions and hemijunctions by multimodal atomic force microscopy

Author keywords

3D structure; Atomic force microscopy; Cell volume regulation; Gap junctions; Hemichannel; Structure function correlation

Indexed keywords

CELL MEMBRANES; CYTOLOGY; ELECTROPHYSIOLOGY; MOLECULAR STRUCTURE;

EID: 0035254181     PISSN: 1059910X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0029(20010201)52:3<273::AID-JEMT1013>3.0.CO;2-M     Document Type: Article
Times cited : (25)

References (76)
  • 1
    • 0023413394 scopus 로고
    • Lateral interactions among membrane proteins
    • Abney JR, Braun J, Owicki JC. 1987. Lateral interactions among membrane proteins. Biophys J 52:441-454.
    • (1987) Biophys J , vol.52 , pp. 441-454
    • Abney, J.R.1    Braun, J.2    Owicki, J.C.3
  • 2
    • 0021839155 scopus 로고
    • Gap junction structures: VII Analysis of connexon images obtained with cationic and anionic negative stains
    • Baker TS, Sosinsky GE, Caspar DLD, Gall C, Goodenough DA. 1985. Gap junction structures: VII Analysis of connexon images obtained with cationic and anionic negative stains. J Mol Biol 184:81-98.
    • (1985) J Mol Biol , vol.184 , pp. 81-98
    • Baker, T.S.1    Sosinsky, G.E.2    Caspar, D.L.D.3    Gall, C.4    Goodenough, D.A.5
  • 4
    • 0021230251 scopus 로고
    • How a gap junction maintains its structure
    • Braun J, Abney JR, Owicki JC. 1984. How a gap junction maintains its structure. Nature 310:316-318.
    • (1984) Nature , vol.310 , pp. 316-318
    • Braun, J.1    Abney, J.R.2    Owicki, J.C.3
  • 5
    • 0025922923 scopus 로고
    • 2+ as extracellular (first) messengers
    • 2+ as extracellular (first) messengers. Physiological Rev 71:371-411.
    • (1991) Physiological Rev , vol.71 , pp. 371-411
    • Brown, E.M.1
  • 6
    • 0029974655 scopus 로고    scopus 로고
    • Connections with connexins: The molecular basis of direct intercellular signaling
    • Bruzzone R, White TW, Paul DL. 1996. Connections with connexins: the molecular basis of direct intercellular signaling. Eur J Biochem 238:1-27.
    • (1996) Eur J Biochem , vol.238 , pp. 1-27
    • Bruzzone, R.1    White, T.W.2    Paul, D.L.3
  • 7
    • 0026657705 scopus 로고
    • Measuring local surface charge densities in electrolyte solutions with a scanning force microscope
    • Butt H-J. 1992. Measuring local surface charge densities in electrolyte solutions with a scanning force microscope. Biophys J 63:578-582.
    • (1992) Biophys J , vol.63 , pp. 578-582
    • Butt, H.-J.1
  • 8
    • 0017682970 scopus 로고
    • Gap junction structures: Correlated electron microscopy and X-ray diffraction
    • Caspar DLD, Goodenough DA, Makowski L, Phillips WC. 1977. Gap junction structures: correlated electron microscopy and X-ray diffraction. J Cell Biol 74:605-628.
    • (1977) J Cell Biol , vol.74 , pp. 605-628
    • Caspar, D.L.D.1    Goodenough, D.A.2    Makowski, L.3    Phillips, W.C.4
  • 11
    • 0023229231 scopus 로고
    • Expression of functional cell-cell channels from cloned rat liver gap junction cDNA
    • Dahl G, Miller T, Paul D, Vollemy R, Werner R. 1987. Expression of functional cell-cell channels from cloned rat liver gap junction cDNA. Science 236:1290-1293.
    • (1987) Science , vol.236 , pp. 1290-1293
    • Dahl, G.1    Miller, T.2    Paul, D.3    Vollemy, R.4    Werner, R.5
  • 13
    • 0000174151 scopus 로고
    • Intercellular connection between smooth muscle cells: The nexus
    • Dewey M, Barr L. 1962. Intercellular connection between smooth muscle cells: the nexus. Science 137:670-672.
    • (1962) Science , vol.137 , pp. 670-672
    • Dewey, M.1    Barr, L.2
  • 14
    • 0026567947 scopus 로고
    • Hemi-gap junction channels in solitary horizontal cells of the catfish retina
    • DeVries, SH, Schwartz EA. 1992. Hemi-gap junction channels in solitary horizontal cells of the catfish retina. J Physiol 445:201-230.
    • (1992) J Physiol , vol.445 , pp. 201-230
    • DeVries, S.H.1    Schwartz, E.A.2
  • 15
    • 0026104841 scopus 로고
    • Atomic force microscopy of synthetic ultrafiltration membranes in air and under water
    • Dietz P, Hansma PK, Herrmann K-H, Inacker O, Lehmann H-D. 1991. Atomic force microscopy of synthetic ultrafiltration membranes in air and under water. Ultramicroscopy 35:155-159.
    • (1991) Ultramicroscopy , vol.35 , pp. 155-159
    • Dietz, P.1    Hansma, P.K.2    Herrmann, K.-H.3    Inacker, O.4    Lehmann, H.-D.5
  • 16
    • 0029738650 scopus 로고    scopus 로고
    • Xenopus connexin38 forms hemi-gap-junctional channels in the non-junctional plasma membrane of Xenopus oocytes
    • Ebihara L. 1996. Xenopus connexin38 forms hemi-gap-junctional channels in the non-junctional plasma membrane of Xenopus oocytes. Biophys J 71:742-748.
    • (1996) Biophys J , vol.71 , pp. 742-748
    • Ebihara, L.1
  • 19
    • 0018647726 scopus 로고
    • Permeability of the cell-to-cell membrane channels in mammalian cell junction
    • Flagg-Newton J, Simpson I, Loewenstein WR. 1979. Permeability of the cell-to-cell membrane channels in mammalian cell junction. Science 205:404-407.
    • (1979) Science , vol.205 , pp. 404-407
    • Flagg-Newton, J.1    Simpson, I.2    Loewenstein, W.R.3
  • 20
    • 0034698297 scopus 로고    scopus 로고
    • Subatomic features on the silicon (111)-(7x7) surface observed by atomic force microscopy
    • Giessibl FJ, Hembacher S, Bielefeldt H, Mannhart J. 2000. Subatomic features on the silicon (111)-(7x7) surface observed by atomic force microscopy. Science 289:422-425.
    • (2000) Science , vol.289 , pp. 422-425
    • Giessibl, F.J.1    Hembacher, S.2    Bielefeldt, H.3    Mannhart, J.4
  • 22
  • 23
    • 0026095474 scopus 로고
    • Atomic force microscopy and dissection of gap junctions
    • Hoh JH, Lal R, John SA, Revel J-P, Arnsdorf MF. 1991. Atomic force microscopy and dissection of gap junctions. Science 253:1405-1408.
    • (1991) Science , vol.253 , pp. 1405-1408
    • Hoh, J.H.1    Lal, R.2    John, S.A.3    Revel, J.-P.4    Arnsdorf, M.F.5
  • 24
    • 0027163746 scopus 로고
    • Structure of the extracellular surface of the gap junction by atomic force microscopy
    • Hoh JH, Sosinsky GE, Revel J-P, Hansma PK. 1993. Structure of the extracellular surface of the gap junction by atomic force microscopy. Biophys J 65:149-163.
    • (1993) Biophys J , vol.65 , pp. 149-163
    • Hoh, J.H.1    Sosinsky, G.E.2    Revel, J.-P.3    Hansma, P.K.4
  • 27
    • 0032765325 scopus 로고    scopus 로고
    • Images of oligomeric Kv beta 2, a modulatory subunit of potassium channels
    • Huizen RV, Czajkowsky DM, Shi D, Shao ZF, Li M. 1999. Images of oligomeric Kv beta 2, a modulatory subunit of potassium channels. FEBS Lett 457:107-111.
    • (1999) FEBS Lett , vol.457 , pp. 107-111
    • Huizen, R.V.1    Czajkowsky, D.M.2    Shi, D.3    Shao, Z.F.4    Li, M.5
  • 30
    • 0030028301 scopus 로고    scopus 로고
    • The gap junction communication channel
    • Kumar N, Gilula NB. 1996. The gap junction communication channel. Cell 84:381-388.
    • (1996) Cell , vol.84 , pp. 381-388
    • Kumar, N.1    Gilula, N.B.2
  • 31
    • 0025569290 scopus 로고
    • Biochemical and immunochemical analysis of the arrangement of connexin43 in heart gap junction membranes
    • Laird DW, Revel J-P. 1990. Biochemical and immunochemical analysis of the arrangement of connexin43 in heart gap junction membranes. J Cell Sci 97:109-117.
    • (1990) J Cell Sci , vol.97 , pp. 109-117
    • Laird, D.W.1    Revel, J.-P.2
  • 32
    • 0028896673 scopus 로고
    • Imaging neurite outgrowth and cytoskeletal reorganization with an atomic force microscope: Studies on PC12 and NIH3T3 cells in culture
    • Lal R, Drake B, Blumberg D, Saner DS, Hansma PK, Feinstein S. 1995a. Imaging neurite outgrowth and cytoskeletal reorganization with an atomic force microscope: studies on PC12 and NIH3T3 cells in culture. Am J Physiol 269:C275-C285.
    • (1995) Am J Physiol , vol.269
    • Lal, R.1    Drake, B.2    Blumberg, D.3    Saner, D.S.4    Hansma, P.K.5    Feinstein, S.6
  • 33
    • 0027669149 scopus 로고
    • Molecular resolution imaging of outer membrane channels reconstituted in an artificial bilayer
    • Lal R, Kim H, Garavito RM, Arnsdorf MF. 1993. Molecular resolution imaging of outer membrane channels reconstituted in an artificial bilayer. Am J Physiol 265:C851-C856.
    • (1993) Am J Physiol , vol.265
    • Lal, R.1    Kim, H.2    Garavito, R.M.3    Arnsdorf, M.F.4
  • 34
    • 0028934828 scopus 로고
    • Heart gap junction preparations reveal hemiplaques by atomic force microscopy
    • Lal R, John SA, Laird DW, Arnsdorf MF. 1995b. Heart gap junction preparations reveal hemiplaques by atomic force microscopy. Am J Physiol 268:C968-C977.
    • (1995) Am J Physiol , vol.268
    • Lal, R.1    John, S.A.2    Laird, D.W.3    Arnsdorf, M.F.4
  • 35
    • 0028157680 scopus 로고
    • Biological application of atomic force microscopy
    • Lal R, John SA. 1994. Biological application of atomic force microscopy. Am J Physiol 266:C1-C21.
    • (1994) Am J Physiol , vol.266
    • Lal, R.1    John, S.A.2
  • 36
    • 0030310593 scopus 로고    scopus 로고
    • Imaging molecular structure of channels and receptors with an atomic force microscope
    • Lal R. 1998. Imaging molecular structure of channels and receptors with an atomic force microscope. Scan Microsc 10:81-96.
    • (1998) Scan Microsc , vol.10 , pp. 81-96
    • Lal, R.1
  • 37
    • 0030646184 scopus 로고    scopus 로고
    • Multimodal imaging with AFM: Combined atomic force, light fluorescence and laser confocal microscopy and electrophysiological recordings of biological membranes
    • Lal R, Proksch R. 1997. Multimodal imaging with AFM: combined atomic force, light fluorescence and laser confocal microscopy and electrophysiological recordings of biological membranes. Int J Imag Syst Technol 8:293-300.
    • (1997) Int J Imag Syst Technol , vol.8 , pp. 293-300
    • Lal, R.1    Proksch, R.2
  • 38
    • 0025054186 scopus 로고
    • The Gap junction-like form of a vacuolar proton channel component appears not to be an artifact of isolation - An immunocytochemical localization study
    • Leitch B, Finbow ME. 1990. The Gap junction-like form of a vacuolar proton channel component appears not to be an artifact of isolation - an immunocytochemical localization study. Exp Cell Res 190: 218-226.
    • (1990) Exp Cell Res , vol.190 , pp. 218-226
    • Leitch, B.1    Finbow, M.E.2
  • 39
    • 0029800089 scopus 로고    scopus 로고
    • Properties and regulation of gap junctional hemichannels in the plasma membranes of cultured cells
    • Li H, Liu T, Lazarak A, Peracchia C, Goldberg GS, Lampe PD, Johnson RG. 1996. Properties and regulation of gap junctional hemichannels in the plasma membranes of cultured cells. J Cell Biol 134:1019-1030.
    • (1996) J Cell Biol , vol.134 , pp. 1019-1030
    • Li, H.1    Liu, T.2    Lazarak, A.3    Peracchia, C.4    Goldberg, G.S.5    Lampe, P.D.6    Johnson, R.G.7
  • 40
    • 4243278990 scopus 로고    scopus 로고
    • Amyloid beta protein (1-42) (AβP) forms tetrameric pores in lipid bilayers: An atomic force microscopic study
    • Lin H, Alig T, Zasadzinski J, Lal R. 2000. Amyloid beta protein (1-42) (AβP) forms tetrameric pores in lipid bilayers: an atomic force microscopic study. Biophys J 78:177A.
    • (2000) Biophys J , vol.78
    • Lin, H.1    Alig, T.2    Zasadzinski, J.3    Lal, R.4
  • 41
    • 0021447833 scopus 로고
    • Cytoplasmic surface and intramembrane components of rat heart gap junction proteins
    • Manjunath CK, Going GE, Page E. 1984. Cytoplasmic surface and intramembrane components of rat heart gap junction proteins. Am J Physiol 246:H865-H875.
    • (1984) Am J Physiol , vol.246
    • Manjunath, C.K.1    Going, G.E.2    Page, E.3
  • 42
    • 0022081022 scopus 로고
    • Cell biology and protein composition of cardiac gap junctions
    • Manjunath CK, Page E. 1985. Cell biology and protein composition of cardiac gap junctions. Am J Physiol 248:H783-H791.
    • (1985) Am J Physiol , vol.248
    • Manjunath, C.K.1    Page, E.2
  • 43
    • 0014906595 scopus 로고
    • The ultrastructure of the nexus. A correlated thin-section and freeze-cleave study
    • Mcnutt NS, Weinstein RS. 1970. The ultrastructure of the nexus. A correlated thin-section and freeze-cleave study. J Cell Biol 47:666-688.
    • (1970) J Cell Biol , vol.47 , pp. 666-688
    • Mcnutt, N.S.1    Weinstein, R.S.2
  • 44
    • 0022471218 scopus 로고
    • Growth inhibition of transformed cells correlates with their junctional communication with normal cells
    • Mehta P, Bertram J, Loewenstein WR. 1986. Growth inhibition of transformed cells correlates with their junctional communication with normal cells. Cell 44:187-196.
    • (1986) Cell , vol.44 , pp. 187-196
    • Mehta, P.1    Bertram, J.2    Loewenstein, W.R.3
  • 45
    • 0024095587 scopus 로고
    • Topology of the 32-kD liver gap junction protein determined by site-directed antibody localizations
    • Milks L, Kumar NM, Houghton R, Unwin N, Gilula NB. 1988. Topology of the 32-kD liver gap junction protein determined by site-directed antibody localizations. EMBO J 7:2967-2975.
    • (1988) EMBO J , vol.7 , pp. 2967-2975
    • Milks, L.1    Kumar, N.M.2    Houghton, R.3    Unwin, N.4    Gilula, N.B.5
  • 46
    • 0029069245 scopus 로고
    • Atomic force microscopy of cholera toxin B-oligomers bound to bilayers of biologically relevant lipids
    • Mou J, Yang J, Shao ZF. 1995. Atomic force microscopy of cholera toxin B-oligomers bound to bilayers of biologically relevant lipids. J Mol Biol 248:507-512.
    • (1995) J Mol Biol , vol.248 , pp. 507-512
    • Mou, J.1    Yang, J.2    Shao, Z.F.3
  • 47
    • 85161732893 scopus 로고
    • Biochemical analysis of connexon assembly
    • Abstract, Hiroshima, Japan
    • Musil L, Goodenough DA. 1993. Biochemical analysis of connexon assembly. Abstract, Biannual Gap Junction meeting, Hiroshima, Japan.
    • (1993) Biannual Gap Junction Meeting
    • Musil, L.1    Goodenough, D.A.2
  • 48
    • 0031471235 scopus 로고    scopus 로고
    • Structural activity of a cloned potassium channel (ROMK1) monitored with the atomic force microscope: The "molecular-sandwich" technique
    • Oberleithner H, Schneider SW, Henderson RM. 1999. Structural activity of a cloned potassium channel (ROMK1) monitored with the atomic force microscope: the "molecular-sandwich" technique. Proc Natl Acad Sci 94:14144-14139.
    • (1999) Proc Natl Acad Sci , vol.94 , pp. 14144-114139
    • Oberleithner, H.1    Schneider, S.W.2    Henderson, R.M.3
  • 49
    • 0001361115 scopus 로고
    • True atomic resolution by atomic force microscopy through repulsive and attractive forces
    • Ohnesorge F, Binnig G. 1993. True atomic resolution by atomic force microscopy through repulsive and attractive forces. Science 260: 1451-1456.
    • (1993) Science , vol.260 , pp. 1451-1456
    • Ohnesorge, F.1    Binnig, G.2
  • 50
    • 0020744391 scopus 로고
    • Freeze-fractured cardiac gap junctions: Structural analysis by three methods
    • Page E, Karrison T, Upshaw-Earley J. 1983. Freeze-fractured cardiac gap junctions: structural analysis by three methods. Am J Physiol 244:H525-H539.
    • (1983) Am J Physiol , vol.244
    • Page, E.1    Karrison, T.2    Upshaw-Earley, J.3
  • 51
    • 0015788841 scopus 로고
    • Studies on the intercalated disk of rat ventricular myocardial cells
    • Page E, McCallister LP. 1973. Studies on the intercalated disk of rat ventricular myocardial cells. J Ultrastruct Res 43:388-411.
    • (1973) J Ultrastruct Res , vol.43 , pp. 388-411
    • Page, E.1    McCallister, L.P.2
  • 52
    • 0029081430 scopus 로고
    • Lipid-Protein interactions and assembly of the 16-kda channel polypeptide from nephrops norvegicus - Studies with spin-label electron spin resonance spectroscopy and electron microscopy
    • Pali T, Finbow ME, Holzenburg A, Findlay JBC, Marsh D. 1995. Lipid-Protein interactions and assembly of the 16-kda channel polypeptide from nephrops norvegicus - studies with spin-label electron spin resonance spectroscopy and electron microscopy. Biochemistry 34:9211-9218.
    • (1995) Biochemistry , vol.34 , pp. 9211-9218
    • Pali, T.1    Finbow, M.E.2    Holzenburg, A.3    Findlay, J.B.C.4    Marsh, D.5
  • 53
    • 0026352039 scopus 로고
    • Connexin 46, a novel lens gap junction protein, induces voltage-gated currents in nonjunctional plasma membrane of Xenopus oocytes
    • Paul DL, Ebihara L, Takemoto LJ, Swenson KI, Goodenough DA. 1991. Connexin 46, a novel lens gap junction protein, induces voltage-gated currents in nonjunctional plasma membrane of Xenopus oocytes. J Cell Biol 115:1077-1089.
    • (1991) J Cell Biol , vol.115 , pp. 1077-1089
    • Paul, D.L.1    Ebihara, L.2    Takemoto, L.J.3    Swenson, K.I.4    Goodenough, D.A.5
  • 54
    • 0032913131 scopus 로고    scopus 로고
    • Gating of cx46 gap junctional hemichannels by calcium and voltage
    • Pfahnl A, Dahl G. 1999. Gating of cx46 gap junctional hemichannels by calcium and voltage. Pflugers Arch 437:345-353.
    • (1999) Pflugers Arch , vol.437 , pp. 345-353
    • Pfahnl, A.1    Dahl, G.2
  • 55
    • 0003115521 scopus 로고
    • Junctional communication and cellular growth control
    • Feldman J, Gilula NB, Pitts JD, editors. London: Chapman and Hall
    • Pitts JD. 1978. Junctional communication and cellular growth control. In: Feldman J, Gilula NB, Pitts JD, editors. Intercellular junctions and synapses, receptors and recognition, series B. London: Chapman and Hall, p 63-79.
    • (1978) Intercellular Junctions and Synapses, Receptors and Recognition, Series B , pp. 63-79
    • Pitts, J.D.1
  • 56
    • 0029818020 scopus 로고    scopus 로고
    • Imaging the internal and external pore structures of membrane in fluid: Tapping mode scanning ion conductance microscopy
    • Proksch RA, Lal R, Hansma PK, Morse D, Stucky G. 1996. Imaging the internal and external pore structures of membrane in fluid: tapping mode scanning ion conductance microscopy. Biophys J 71: 2155-2157.
    • (1996) Biophys J , vol.71 , pp. 2155-2157
    • Proksch, R.A.1    Lal, R.2    Hansma, P.K.3    Morse, D.4    Stucky, G.5
  • 57
    • 0034611012 scopus 로고    scopus 로고
    • Physiological role of gap junction hemichannels: Extracellular calcium-dependent isosmotic volume regulation
    • Quist AP, Rhee SK, Lin H, Lal R. 2000. Physiological role of gap junction hemichannels: extracellular calcium-dependent isosmotic volume regulation. J Cell Biol 148:1063-1074.
    • (2000) J Cell Biol , vol.148 , pp. 1063-1074
    • Quist, A.P.1    Rhee, S.K.2    Lin, H.3    Lal, R.4
  • 58
    • 0014097086 scopus 로고
    • Hexagonal array of subunits in intercellular junctions in the mouse heart and liver
    • Revel J-P, Karnovsky M. 1967. Hexagonal array of subunits in intercellular junctions in the mouse heart and liver. J Cell Biol 33:C7-C12.
    • (1967) J Cell Biol , vol.33
    • Revel, J.-P.1    Karnovsky, M.2
  • 60
    • 0001176916 scopus 로고
    • The occurrence of a subunit pattern in the unit membranes of club endings in Mauthner cell synapse in the goldfish brain
    • Robertson JD. 1963. The occurrence of a subunit pattern in the unit membranes of club endings in Mauthner cell synapse in the goldfish brain. J Cell Biol 19:201-221.
    • (1963) J Cell Biol , vol.19 , pp. 201-221
    • Robertson, J.D.1
  • 61
    • 0021508612 scopus 로고
    • The role of connexon aggregate fusion in gap junction growth
    • Ryerse JS, Nagel BA, Hammel I. 1984. The role of connexon aggregate fusion in gap junction growth. J Submicrosc Cytol 16:649-657.
    • (1984) J Submicrosc Cytol , vol.16 , pp. 649-657
    • Ryerse, J.S.1    Nagel, B.A.2    Hammel, I.3
  • 63
    • 0027446946 scopus 로고
    • Charge transport by ion translocating membrane proteins on solid supported membranes
    • Seifert K, Fendler K, Bamberg E. 1993. Charge transport by ion translocating membrane proteins on solid supported membranes. Biophys J 64:384-391.
    • (1993) Biophys J , vol.64 , pp. 384-391
    • Seifert, K.1    Fendler, K.2    Bamberg, E.3
  • 64
    • 0018535176 scopus 로고
    • Metabolic interactions between animal cells through permeable intercellular junctions
    • Sheridan JD, Finbow ME, Pitts JD. 1979. Metabolic interactions between animal cells through permeable intercellular junctions. Exp Cell Res 123:111-117.
    • (1979) Exp Cell Res , vol.123 , pp. 111-117
    • Sheridan, J.D.1    Finbow, M.E.2    Pitts, J.D.3
  • 65
    • 0026484453 scopus 로고
    • Image analysis of gap junction structures
    • Sosinsky GE. 1992. Image analysis of gap junction structures. Electron Microsc Rev 5:59-76.
    • (1992) Electron Microsc Rev , vol.5 , pp. 59-76
    • Sosinsky, G.E.1
  • 67
    • 0029989165 scopus 로고    scopus 로고
    • Protein tracking and observation of protein motion using atomic force microscope
    • Thomson NH, Fritz M, Cleveland JP, Schmidt CF, Hansma PK. 1996. Protein tracking and observation of protein motion using atomic force microscope. Biophys J 70:2421-2431.
    • (1996) Biophys J , vol.70 , pp. 2421-2431
    • Thomson, N.H.1    Fritz, M.2    Cleveland, J.P.3    Schmidt, C.F.4    Hansma, P.K.5
  • 69
    • 0033582686 scopus 로고    scopus 로고
    • Three-dimensional structure of a recombinant gap junction membrane channel
    • Unger VM, Kumar NM, Gilula NB, Yeager M. 1999. Three-dimensional structure of a recombinant gap junction membrane channel. Science 283:1176-1180.
    • (1999) Science , vol.283 , pp. 1176-1180
    • Unger, V.M.1    Kumar, N.M.2    Gilula, N.B.3    Yeager, M.4
  • 70
    • 0021139243 scopus 로고
    • Two configurations of a channel-forming membrane protein
    • Unwin PNT, Ennis PD. 1984. Two configurations of a channel-forming membrane protein. Nature 307:609-613.
    • (1984) Nature , vol.307 , pp. 609-613
    • Unwin, P.N.T.1    Ennis, P.D.2
  • 71
    • 0018905597 scopus 로고
    • Structure of gap junctions between communication cells
    • Unwin PNT, Zampighi G. 1980. Structure of gap junctions between communication cells. Nature 282:545-549.
    • (1980) Nature , vol.282 , pp. 545-549
    • Unwin, P.N.T.1    Zampighi, G.2
  • 72
    • 0028892754 scopus 로고
    • Clustering of Cx43 cell-to-cell channels into gap junction plaques: Regulation by cAMP and microfilaments
    • Wang Y, Rose B. 1995. Clustering of Cx43 cell-to-cell channels into gap junction plaques: regulation by cAMP and microfilaments. J Cell Sci 108:3501-3508.
    • (1995) J Cell Sci , vol.108 , pp. 3501-3508
    • Wang, Y.1    Rose, B.2
  • 73
    • 0022370503 scopus 로고
    • Translation and functional expression of cell-cell channel mRNA in Xenopus oocytes
    • Werner R, Miller T, Azarnia R, Dahl G. 1985. Translation and functional expression of cell-cell channel mRNA in Xenopus oocytes. J Membr Biol 87:253-268.
    • (1985) J Membr Biol , vol.87 , pp. 253-268
    • Werner, R.1    Miller, T.2    Azarnia, R.3    Dahl, G.4
  • 74
    • 0024356206 scopus 로고
    • The 43-KD polypeptide of heart gap junctions: Immunolocalization, topology, and functional domains
    • Yancey SB, John SA, Lal R, Austin BJ, Revel J-P. 1989. The 43-KD polypeptide of heart gap junctions: Immunolocalization, topology, and functional domains. J Cell Biol 108:2241-2254.
    • (1989) J Cell Biol , vol.108 , pp. 2241-2254
    • Yancey, S.B.1    John, S.A.2    Lal, R.3    Austin, B.J.4    Revel, J.-P.5
  • 75
    • 0026515179 scopus 로고
    • Membrane topology and quaternary structure of cardiac gap junction ion channels
    • Yeager M, Gilula NB. 1992. Membrane topology and quaternary structure of cardiac gap junction ion channels. J Mol Biol 223:929-948.
    • (1992) J Mol Biol , vol.223 , pp. 929-948
    • Yeager, M.1    Gilula, N.B.2
  • 76
    • 0032903938 scopus 로고    scopus 로고
    • Functional and morphological correlates of connexin50 expressed in Xenopus laevis oocytes
    • Zampighi GA, Loo DFD, Kremin M, Eskandari S, Wright EM. 1999. Functional and morphological correlates of connexin50 expressed in Xenopus laevis oocytes. J Gen Physiol 113:507-523.
    • (1999) J Gen Physiol , vol.113 , pp. 507-523
    • Zampighi, G.A.1    Loo, D.F.D.2    Kremin, M.3    Eskandari, S.4    Wright, E.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.