Selective inhibition of human mast cell tryptase by gabexate mesylate, an antiproteinase drug

Biochemical Pharmacology

Volumn 61, Issue 3, 2001, Pages 271-276

  Erba, Fulvio ^a,c   Fiorucci, Laura ^a   Pascarella, Stefano ^b   Menegatti, Enea ^c   Ascenzi, Paolo ^d   Ascoli, Franca ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF FERRARA   (Italy)

^d ROMA TRE UNIVERSITY   (Italy)

Author keywords

Bovine tryptase; Enzyme inhibition; Gabexate mesylate; Human tryptase; Structural aspects

Indexed keywords

ANTICOAGULANT AGENT; GABEXATE MESILATE; SERINE PROTEINASE INHIBITOR; TRYPTASE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVITY; FIBRINOGENOLYSIS; HEMODIALYSIS; HUMAN; HUMAN CELL; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEINASE INHIBITION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; CATTLE; CELLS, CULTURED; GABEXATE; HUMANS; KINETICS; MAST CELLS; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPTASES;

EID: 0035253833     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(00)00550-5     Document Type: Article

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