Effect of antenatal betamethasone treatment on microtubule-associated proteins MAP1B and MAP2 in fetal sheep

Journal of Physiology

Volumn 530, Issue 3, 2001, Pages 497-506

  Schwab, Matthias ^a,b   Antonow Schlorke, Iwa ^a   Kühn, Birgit ^a,b   Müller, Thomas ^a,b   Schubert, Harald ^a,b   Walter, Bernd ^a,b   Sliwka, Ulrich ^a,b   Nathanielsz, Peter W ^a,b  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETAMETHASONE; BETAMETHASONE ACETATE PLUS BETAMETHASONE SODIUM PHOSPHATE; CYTOSKELETON PROTEIN; DRUG VEHICLE; EOSIN; GLUCOCORTICOID; HEMATOXYLIN; ISOPROTEIN; MICROSPHERE; MICROTUBULE ASSOCIATED PROTEIN 2; MICROTUBULE ASSOCIATED PROTEIN 5; MONOCLONAL ANTIBODY; PARAFFIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN DEVELOPMENT; CAUDATE NUCLEUS; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG BLOOD LEVEL; DRUG EFFECT; FETUS; FETUS DEVELOPMENT; FETUS LUNG MATURATION; FRONTAL CORTEX; GESTATION PERIOD; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LEFT HEMISPHERE; METABOLIC DISORDER; MORPHOGENESIS; NERVE CELL; NERVE CELL LESION; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROTEIN DEPLETION; PUTAMEN; SHEEP; BLOOD LEVEL; BRAIN NERVE CELL; BRAIN REGION; CAUDATE PUTAMEN; CELL DAMAGE; PRENATAL CARE; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ANIMALS; ANTIBODIES, MONOCLONAL; BETAMETHASONE; BRAIN; CAUDATE NUCLEUS; FEMALE; FETAL BLOOD; FRONTAL LOBE; GESTATIONAL AGE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INFUSIONS, INTRAVENOUS; MATERNAL-FETAL EXCHANGE; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; PREGNANCY; PROTEIN ISOFORMS; PUTAMEN; SHEEP;

EID: 0035252987     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2001.0497k.x     Document Type: Article

References (57)

1. Type I corticosteroid receptor-like immunoreactivity in the rat CNS: Distribution and regulation by corticosteroids
2. Human microtubule-associated protein-2c localizes to dendrites and axons in fetal spinal motor neurons
3. Human fetal hippocampal development: II. The neuronal cytoskeleton
4. Scientific basis and therapeutic regimens for use of antenatal glucocorticoids
5. Microtubule-associated protein 2 (MAP-2): A sensitive marker of seizure-related brain damage
6. Colchicine induces apoptosis in cerebellar granule cells
7. Ontogeny of microtubule-associated protein 2 in rat cerebellum: Differential expression of the doublet polypeptides
8. Dendrite loss is a characteristic early indicator of toxin-induced neurodegeneration in rat midbrain slices
9. Cytoskeletal involvement in neuronal learning: A review
10. Stress, glucocorticoids and development
11. A comparative study of cardiovascular, endocrine and behavioural effects of betamethasone and dexamethasone administration to fetal sheep
12. Comparative aspects of the brain growth spurt
13. Calpain-mediated proteolysis of microtubule associated proteins MAP1B and MAP2 in developing brain
14. Disruption of MAP-2 immunostaining in rat hippocampus after traumatic brain injury
15. Recovery of protein synthesis in tolerance-induced hippocampal CA1 neurons after transient forebrain ischemia
16. Exacerbation of apoptosis in the dentate gyrus of the aged rat by dexamethasone and the protective role of corticosterone
17. Temporal response and effects of excitatory amino acid antagonism on microtubule-associated protein 2 immunoreactivity following experimental brain injury in rats
18. Glucocorticoids inhibit glucose transport in cultured hippocampal neurons and glia
19. DNA, ganglioside and sulfatide in brains of rats given corticosterone in infancy, with an estimate of cell loss during development
20. The role of microtubule-associated protein 2 (MAP2) in neuronal growth, plasticity and degeneration
21. Degradation of microtubule-associated protein 2 and brain spectrin by calpain: A comparative study
22. Corticosteroid receptors in brain: Relationship of receptors to effects in stress and aging
23. Stress and the brain: A paradoxical role for adrenal steroids
24. Hypoxic-ischemic injury acutely disrupts microtubule-associated protein 2 immunostaining in neonatal rat brain
25. Microtubule-associated protein 2 as an early indicator of ischemia-induced neurodegeneration in the gerbil forebrain
26. Microtubule-associated proteins and the determination of neuronal form
27. The low molecular weight form of microtubule-associated protein 2 is transported into both axons and dendrites
28. Biochemical effects of corticosteroids on neural tissues
29. Antenatal corticosteroid therapy and fetal behaviour: A randomised study of the effects of betamethasone and dexamethasone
30. Selective neuronal toxicity of cocaine in embryonic mouse brain cocultures
31. The relationship between myometrial activity and sleep state and breathing in fetal sheep throughout the last third of gestation
32. Ethanol induces MAP2 changes in organotypic hippocampal slice cultures
33. Sequence of neuronal responses assessed by immunohistochemistry in the newborn rat brain after hypoxia-ischemia
34. Glucocorticoid endangerment of the hippocampus: Tissue, steroid and receptor specificity
35. Microtubular proteolysis in focal cerebral ischemia
36. Developmental regulation of MAP2 variants during neuronal differentiation in vitro
37. Hypoxemia near mid-gestation has long-term effects on fetal brain development
38. Two receptor systems for corticosterone in rat brain: Microdistribution and differential occupation
39. Differential expression of distinct microtubule-associated proteins during brain development
40. Glucocorticoid receptors in sheep brain tissues during development
41. Reexpression of developmentally regulated MAP2c mRNA after ischemia: Colocalization with hsp72 mRNA in vulnerable neurons
42. Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function
43. The physiological relevance of glucocorticoid endangerment of the hippocampus
44. Nonlinear investigation of developmental changes of the ECoG activity in fetal sheep
45. Brain-derived peptides reduce the size of cerebral infarction and loss of MAP2 immunoreactivity after focal ischemia in rats
46. Effects of betamethasone administration to the fetal sheep in late gestation on fetal cerebral blood flow
47. Non-linear changes of electrocortical activity after antenatal betamethasone treatment in fetal sheep
48. Effects of dexamethasone and betamethasone on fetal heart rate variability in preterm labour: A randomised study
49. The ontogeny of fetal lamb electrocortical activity: A power spectral analysis
50. Microtubule antagonists activate programmed cell death (apoptosis) in cultured rat hepatocytes
51. The roles of microtubule-associated proteins in brain morphogenesis: A review
52. Differential localization of the high- and low-molecular weight variants of MAP2 in the developing retina
53. Neuronal microtubule-associated proteins in the embryonic avian spinal cord
54. Neurotoxicity of glucocorticoids in the primate brain
55. Phylogenetic conservation of brain microtubule-associated proteins MAP2 and tau
56. Changes in glucocorticoid receptor number in the hypothalamus and pituitary of the sheep fetus with gestational age and after adrenocorticotropin treatment