An arginine/glutamine difference at the juxtaposition of transmembrane domain 6 and the third extracellular loop contributes to the markedly different nucleotide selectivities of human and canine P2y11 receptors

Molecular Pharmacology

Volumn 60, Issue 6, 2001, Pages 1375-1382

  Qi, A D ^a   Zambon, A C ^a   Insel, P A ^a   Nicholas, R A ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYLTHIOADENOSINE 5' DIPHOSPHATE; 2 METHYLTHIOADENOSINE 5' TRIPHOSPHATE; ADENINE NUCLEOTIDE DERIVATIVE; ADENOSINE 5' O (THIODIPHOSPHATE); ADENOSINE 5' O (THIOTRIPHOSPHATE); ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; ADENYLATE CYCLASE; ARGININE; CALCIUM; CIBACRON BLUE F3GA; CYCLIC AMP; GLUTAMINE; INOSITOL PHOSPHATE; NUCLEOTIDE; PHOSPHOLIPASE C; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PURINERGIC RECEPTOR STIMULATING AGENT; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; SURAMIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CALCIUM MOBILIZATION; CHO CELL; DRUG POTENCY; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; RECEPTOR BINDING; SPECIES DIFFERENCE;

EID: 0035218329     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.60.6.1375     Document Type: Article

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