Effect of insulin on von Willebrand factor release in normal and diabetic subjects: In vivo and in vitro studies

Hormone and Metabolic Research

Volumn 33, Issue 11, 2001, Pages 674-680

  Kessler, L ^a   Azimzadeh, A ^b   Wiesel, M L ^c   Coumaros, G ^d   Chakfe N ^a   Soyer, C ^c   Koehl, C ^d   Cazenave, J R ^c   Wolf, P ^b   Pinget, M ^a  

^a UNIVERSITY HOSPITAL OF STRASBOURG   (France)

^b Transplantation Foundation   (France)

^c ETABLISSEMENT FRANÇAIS DU SANG   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Diabetes; Endothelial Cell; Insulin; Von Willebrand Factor

Indexed keywords

ENDOTHELIN 1; INSULIN; VON WILLEBRAND FACTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DIABETES MELLITUS; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HYPERINSULINEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; MALE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN SECRETION;

ADULT; BLOOD GLUCOSE; C-REACTIVE PROTEIN; CELLS, CULTURED; DIABETES MELLITUS; ENDOTHELINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; HYPERINSULINISM; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MICROSCOPY, PHASE-CONTRAST; MIDDLE AGED; PLASMINOGEN INACTIVATORS; THROMBIN; VON WILLEBRAND FACTOR;

EID: 0035217969     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2001-18686     Document Type: Article

References (30)

1. Endothelial dysfunction and pathogenesis of diabetic angiopathy
2. Von Willebrand factor, C-reactive protein, and 5-year mortality in diabetic and non-diabetic subjects: The Hoorn study
3. Endothelial dysfunction precedes development of microalbuminuria in IDDM
4. Elevated von Willebrant factor antigen predicts deterioration in diabetic peripheral nerve function
5. Elevated glucose concentrations increase factor VIIIR: Ag levels in human umbilical vein endothelial cells
6. Increased Ievels of soluble adhesion molecules in type 2 (non-insulin dependent) diabetes mellitus are independent of glycaemic control
7. Acute hyperglycemia increases soluble P-selectin in male patients with mild diabetes mellitus
8. Insulin sensitivity in patients with essential hypertension: No influence of the ACE inhibitor enalapril
9. Endothelial dysfunction: Cause of the insulin resistance syndrome
10. Insulin increases the release of endothelin in endothelial cell cultures in vitro but not in vivo
11. Insulin stimulates endothelin-1 secretion from human endothelial cells and modulated its circulating levels in vivo
12. Plasminogen activator inhibitor-1 in nonobese subjects with non-insulin-dependent diabetes mellitus
13. Associations of factor VIII and von Willebrand factor with age, race, sex, and risk factors for atherosclerosis
14. Von Willebrand factor in cultured human vascular endothelial cells from adult and umbilical cord arteries and veins
15. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
16. Comparative study of target antigens for primate xenereactive natural antibodies in pig and rat endothelial cells
17. Hyperunsulinema, hyperglycemia and impaired hemostasis: The flamingham offspring study
18. Factors responsible for impaired fibrinolysis in obese subjects and NIDDM patients
19. Adverse influence of cigarette smoking on the endothelium
20. Von Willebrand factor, the endothelium and obesity
21. Von Willebrand factor (vWf) as a plasma marker of endothelial activation in diabetes: Improved reliability with parallel determination of the vWf propeptide (vWf/Agll)
22. Levels of von Willebrand factor, insulin resistance syndrome and a common vWf gene polymorphism in non-insulin-dependant (type 2) diabetes mellitus
23. Effects of hyperinsulinemia on plasma levels of circulating adhesion molecules
24. Increased plasma levels of endothelin-1 and von Willebrand factor in patients with type 2 diabetes and dyslipidemia
25. Elevated concentrations of soluble E-selectin and vascular cell adhesion molecule-1 in NIDDM. Effect of intensive insulin treatment
26. Complement proteins C5b-9 Induce secretion of high molecular weight multimers of endothelial von Willebrand factor and translocation of granule membrane protein GMP-140 to the cell surface
27. Insulin stimulates production and secretion of endothelin from bovine endothelial cells
28. Effects of ACE inhibition on spontaneous and insulin-stimulated endothelin-1 secretion: In vitro and in vivo studies
29. Aortic endothelial cell von Willebrand factor content and circulating plasminogen activator inhibitor-1 are increased but expression of endothelial leucocyte adhesion molecules is unchanged in insulin-dependent diabetic BB rats
30. Vascular wall von Willebrand factor in human diabetic retinopathy