Insulin sensitivity in patients with essential hypertension: No influence of the ACE inhibitor Enalapril

Hormone and Metabolic Research

Volumn 31, Issue 7, 1999, Pages 418-423

  Heise, Tim ^a   Heinemann, L ^a   Kristahn, K ^a   Berger, M ^a   Sawicki, P T ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

ACE Inhibitor; Calcium Channel Blocker; Hypertension; Potassium Homeostasis; Two Step Hyperinsulinemic Euglycemic Glucose Clamp

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; NITRENDIPINE;

ADULT; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY MASS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ESSENTIAL HYPERTENSION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN SENSITIVITY; MALE; ORAL DRUG ADMINISTRATION; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL;

ENA;

EID: 0032810189     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-978766     Document Type: Article

References (38)

1. 1 Pollare T, Lithell H, Berne C. A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension. N Engl J Med 1989; 321: 868-873
2. 2 Gans RO, Bilo HJ, Nauta JJ, Popp-Snijders C, Heine RJ, Donker AJ. The effect of angiotensin-1 converting enzyme inhibition on insulin action in healthy volunteers. Eur J Clin Invest 1991; 21: 527-533
3. 3 Torlone E, Rambotti AM, Periello G, Santeusanio F, Brunetti P, Bolli GB. ACE-inhibition increases hepatic and extrahepatic sensitivity to insulin in patients with type 2 (non-insulin-dependent) diabetes mellitus and arterial hypertension. Diabetologia 1991; 34: 119-125
4. 4 Rett K, Wicklmayr M, Tschollar G, Dietze G, Mehnert H. Role of angiotensin-converting enzyme inhibitors in early anti-hypertensive treatment in non-insulin-dependent diabetes mellitus. Postgrad Med J 1988; 64 (suppl 3): 69-74
5. 5 Torlone E, Britta M, Rambotti AM, Periello G, Santeusanio F, Brunetti P, Bolli GB. Improved insulin action and glycemic control after long-term angiotensin-converting enzyme inhibition in subjects with arterial hypertension and type II diabetes. Diabetes Care 1993; 16: 1347-1355
6. 6 Ferriere M, Lachkar H, Richard JL, Bringen J, Orsetti A, Mirouze J. Captopril and insulin sensitivity. Ann Intern Med 1985; 102: 134-135
7. 7 Berne C, Pollare T, Lithell H. Effects of anti-hypertensive treatment on insulin sensitivity with special reference to ACE inhibitors. Diabetes Care 1991; 14 (suppl 4): 39-47
8. 8 Seefeldt T, Orskov L, Mengel A, Rasmussen O, Pedersen MM, Moller N, Christiansen JS, Schmitz O. Lack of effects of angiotensin converting enzyme (ACE) inhibitors on glucose metabolism in type 1 diabetes. Diabetic Med 1990; 7: 700-704
9. 9 Helve E, Touminen JA, Koivisto VA. Captopril does not acutely enhance insulin sensitivity. J Int Med 1993; 234: 41-44
10. 10 Prince MJ, Stuart CA, Padia M, Bandi Z, Holland OB. Metabolic effects of hydrochlorothiazide and enalapril during treatment of the hypertensive diabetic patients. Enalapril for hypertensive diabetics. Arch Int Med 1988; 148: 2363-2368
11. 11 Santoro D, Natali A, Palombo C, Brandi LS, Piatti M, Ghione S, Ferrannini E. Effects of chronic angiotensin converting enzyme inhibition on glucose tolerance and insulin sensitivity in essential hypertension. Hypertension 1992; 20: 181-191
12. 12 Heinemann L, Heise T, Ampudia J, Sawicki P, Sindelka G, Brunner G, Starke AAR. Four week administration of an ACE-inhibitor and a cardioselective beta-blocker in healthy volunteers: no influence on insulin sensitivity. Eur J Clin Invest 1995; 25: 595-600
13. 13 Ludvik B, Kueenburg E, Brunnbauer M, Schernthaner G, Prager R. The effects of ramipril on glucose tolerance, insulin secretion and insulin sensitivity in patients with hypertension. J Cardiovasc Pharm 1991; 18 (suppl 2): S157-S159
14. 14 Hughes TA, Gwynne JT, Switzer BR, Herbst C, White G. Effects of caloric restriction and weight loss on glycemic control, insulin release and resistance, and atherosclerotic risk in obese patients with type 2 diabetes mellitus. Am J Med 1984; 77: 7-17
15. 15 Watts NB, Spanheimer RG, DiGirolamo M, Gebhart SS, Musey VC, Siddiq YK, Phillips LS. Prediction of glucose response to weight loss in patients with non-insulin-dependent diabetes mellitus. Arch Int Med 1990; 150: 803-806
16. 16 Davidson MB, Harris MD, Rosenberg CS. Inverse relationship of metabolic clearance rate of insulin to body mass index. Metabolism 1987; 36: 219-222
17. 17 DeFronzo RA, Ferrannini E. Influence of plasma glucose and insulin concentration on plasma glucose clearance in man. Diabetes 1982; 31: 683-688
18. 18 Vërdonk CA, Rizza RA, Gerich JE. Effects of plasma glucose concentration on glucose utilization and glucose clearance in normal man. Diabetes 1981; 30: 535-537
19. 19 Doberne L, Greenfield MS, Rosenthal M, Widstrom A, Reaven G. Effect of variations in basal plasma glucose concentration on glucose utilization (M) and metabolic clearance (MCR) rates during insulin clamp studies in patients with non-insulin-dependent diabetes mellitus. Diabetes 1982; 31: 396-400
20. 20 Heise T, Rave K, Weyer C, Heinemann L. Measurement of insulin sensitivity with the euglycemic clamp technique: methodological pitfalls. Int J Diabetes 1998; 6: 70-75
21. 21 DeFronzo RA, Felig P, Ferrannini E, Wahren J. Effect of graded doses of insulin on splanchnic and peripheral potassium metabolism in man. Am J Physiol 1980; 238: E421-E427
22. 22 Trovati M, Massucco P, Anfossi G, Cavalot F, Mularoni E, Mattiello L, Rocca G, Emanuelli G. Insulin influences the renin-angiotensin-aldosterone system in humans. Metabolism 1989; 38: 501-503
23. 23 Ferrannini E, Galvan AQ, Santoro D, Natali A. Potassium as a link between insulin and the renin-angiotensin-aldosterone system. J Hypertension 1992; 10 (suppl 1): S5-S10
24. 24 Starke AAR. Determination of insulin sensitivity: Methodological considerations. J Cardiovasc Pharmacol 1992; 20 (suppl 11): S17-S21
25. 25 Groop LC, Widen E, Ferrannini E. Insulin resistance and insulin deficiency in the pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: errors of metabolism or of methods? Diabetologia 1993; 36: 1326-1331
26. 26 Rossetti L, Klein-Robbenhaar G, Giebisch G, Smith D, DeFronzo R. Effect of insulin on renal potassium metabolism. Am J Physiol 1987; 252: F60-F64
27. 27 Bia MJ, DeFronzo RA. Extrarenal potassium homeostasis. Am J Physiol 1981; 240: F257-F268
28. 28 Weinberger MH. Mechanisms of diuretic effects on carbohydrate tolerance, insulin sensitivity and lipid levels. Eur Heart J 1992; 13 (suppl G): 5-9
29. 29 Andersson OK, Gudbrandsson T, Jamerson K. Metabolic adverse effects of thiazide diuretics: the importance of normokalemia. J Int Med 1991; 229 (suppl 2): 89-96
30. 30 Pickkers P, Schachter M, Hughes AD, Feher MD, Sever PS. Thiazide-induced hyperglycemia: a role for calcium-activated potassium channels? Diabetologia 1996; 39: 861-864
31. 31 Trost BN, Weidmann P. Effects of calcium antagonists on glucose homeostasis and serum lipids in non-diabetic and diabetic subjects: a review. J Hypertension 1987; 5 (suppl): S81-5104
32. 32 Andronico G, Piazza G, Mangano MT, Mule G, Carone MB, Cerasola G. Nifedipine vs. enalapril in treatment of hypertensive patients with glucose intolerance. J Cardiovasc Pharmacol 1991; 18 (suppl 10): S52-S54
33. 33 Cabezas-Cerrato J, Garcia-Estevez DA, Araujo D, Iglesis M. Insulin sensitivity, glucose effectiveness, and β-cell function in obese males with essential hypertension: investigation of the effects of treatment with a calcium channel blocker (diltiazem) or an angiotensin-converting enzyme inhibitor (quinapril). Metabolism 1997; 46: 173-178
34. 34 Bergman RN, Finegood DT, Ader M. Assessment of insulin sensitivity in vivo. Endocr Rev 1985; 6: 45-86
35. 35 Bergman RN. Towards physiological understanding of glucose tolerance. Minimal-model approach. Diabetes 1989; 38: 1512-1527
36. 35 Ferrannini E, Buzzigoli G, Bonadonna R, Giorice MA, Oleggini M, Graziadei L, Pedrinelli R, Brandi L, Belvilacqua S. Insulin resistance in essential hypertension. N Engl J Med 1987; 317: 350-357
37. 37 Shen DC, Shieh SM, Fuh MMT, Wu DA, Chen YDI, Reaven GM. Resistance to insulin-stimulated-glucose uptake in patients with hypertension. J Clin Endocrinol Metab 1988; 66: 580-583
38. 38 Reaven GM. Insulin resistance, hyperinsulinemia, hypertrigylceridemia, and hypertension. Parallels between human disease and rodent models. Diabetes Care 1991; 14: 195-202