The effect of glutamate infusion on cardiac performance is independent of changes in metabolism in patients undergoing routine coronary artery bypass surgery

Clinical Science

Volumn 101, Issue 6, 2001, Pages 573-580

  Langenberg, C J ^a   Pietersen, H G ^a   Geskes, G ^a   Wagenmakers, A J M ^a   De Lange, S ^a   Schouten, H J ^a   Soeters, P B ^a  

^a JEROEN BOSCH HOSPITAL   (Netherlands)

Author keywords

Coronary artery bypass graft; Glutamate supplementation; Myocardial metabolism

Indexed keywords

FATTY ACID; GLUCOSE; GLUTAMIC ACID; LACTIC ACID; PLACEBO;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS SURGERY; CORONARY ARTERY DISEASE; DOUBLE BLIND PROCEDURE; FATTY ACID METABOLISM; FEMALE; GLUCOSE UTILIZATION; HEART AFTERLOAD; HEART MUSCLE BLOOD FLOW; HEART MUSCLE OXYGEN CONSUMPTION; HEART PERFORMANCE; HEMODYNAMICS; HUMAN; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SYSTEMIC VASCULAR RESISTANCE;

ADULT; AGED; BLOOD GLUCOSE; CARDIAC OUTPUT; CORONARY ARTERY BYPASS; CORONARY VESSELS; DOUBLE-BLIND METHOD; FATTY ACIDS, NONESTERIFIED; GLUTAMIC ACID; HEART; HEMODYNAMIC PROCESSES; HUMANS; INFUSIONS, INTRAVENOUS; LACTIC ACID; MIDDLE AGED; MYOCARDIUM; OXYGEN; POSTOPERATIVE CARE; VASCULAR RESISTANCE;

EID: 0035215030     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20010063     Document Type: Article

References (24)

1. Myocardial exchanges of glutamate, alanine and citrate in controls and patients with coronary artery disease
2. Antiischemic and metabolic effects of glutamate during pacing in patients with stable angina pectoris secondary to either coronary artery disease or syndrome X
3. Myocardial metabolism of glutamate and left ventricular function in patients with coronary arterial disease
4. Myocardial substrate uptake and oxidation during and after routine cardiac surgery
5. Trauma metabolism and the heart: Studies of heart and leg amino acid flux after cardiac surgery
6. Trauma metabolism and the heart. Uptake of substrates and effects of insulin early after cardiac operations
7. Persistent changes in myocardial glucose metabolism in vivo during reperfusion of a limited-duration coronary occlusion
8. Cardiac metabolism and performance during L-glutamic acid infusion in postoperative cardiac failure
9. Glutamate and high-dose glucose-insulin-potassium (GIK) in the treatment of severe cardiac failure after cardiac operations
10. Mechanisms of myocardial protection by amino acids: Facts and hypotheses
11. Association of myocardial glutamate and aspartate pool and functional recovery of postischemic heart
12. The relationship between the cardiac contractile function, adenine nucleotides and amino acids of cardiac tissue and mitochondria at acute respiratory hypoxia
13. Animal life without oxygen: Basic biochemical mechanisms
14. Anaerobic rat heart. Effects of glucose and tricarboxylic acid-cycle metabolites on metabolism and physiological performance
15. Augmented conversion of aspartate and glutamate to succinate during anoxia in rabbit heart
16. The effects of aspartate and 2-oxoglutarate upon glycolytic energy metabolites and mechanical recovery following global ischaemia in isolated rat hearts
17. Protection of ischemic rabbit myocardium by glutamic acid
18. Changes in myocardial concentration of glutamate and aspartate during coronary artery surgery
19. Glutamate metabolism of the heart during coronary artery bypass grafting
20. Assessment of myocardial glutamate requirements early after coronary artery bypass surgery
21. Haemodynamic stability with midazolam-sufentanil analgesia in cardiac surgical patients
22. Effects of nitroglycerin infusion on segmental wall motion abnormalities after anesthetic induction
23. Metabolic and hemodynamic effects of intravenous glutamate infusion early after coronary operations
24. Effects of glutamate on exercise tolerance and circulating substrate levels in stable angina pectoris