Metabolic and hemodynamic effects of intravenous glutamate infusion early after coronary operations

Journal of Thoracic and Cardiovascular Surgery

Volumn 112, Issue 6, 1996, Pages 1468-1477

  Svedjeholm, R ^a   Vanhanen, I ^a   Hakanson, E ^a   Joachimsson, P O ^a   Jorfeldt, L ^a   Nilsson, L ^a  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; FATTY ACID; GLUCOSE; GLUTAMIC ACID; LACTIC ACID; OXYGEN; SODIUM CHLORIDE;

ADULT; AEROBIC METABOLISM; AMINO ACID BLOOD LEVEL; AMINO ACID TRANSPORT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; HEART LEFT VENTRICLE WORK; HEART MUSCLE METABOLISM; HEART MUSCLE OXYGEN CONSUMPTION; HEMODYNAMICS; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; PRIORITY JOURNAL;

EID: 0030461196     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5223(96)70005-3     Document Type: Article

References (29)

1. R Svedjeholm E Hakanson I Vanhanen Rationale for metabolic support with amino acids and glucose-insulin-potassium (GIK) in cardiac surgery Ann Thorac Surg 59 1995 S15 S22
2. KH Teoh DA Mickle RD Weisel Decreased postoperative myocardial free fatty acid oxidation J Surg Res 44 1988 36 44
3. S Svensson R Svedjeholm R Ekroth Trauma metabolism and the heart: uptake of substrates and effects of insulin early after cardiac operations J THORAC CARDIOVASC SURG 99 1990 1063 1073
4. R Svedjeholm R Ekroth PO Joachimsson G Ronquist SE Svensson H. Tydén Myocardial uptake of amino acids and other substrates in relation to myocardial oxygen consumption four hours after cardiac surgery J THORAC CARDIOVASC SURG 101 1991 688 694
5. HL Lazar GD Buckberg AJ Manganaro H. Becker Myocardial energy replenishment and reversal of ischemic damage by substrate enhancement of secondary blood cardioplegia with amino acids during reperfusion J THORAC CARDIOVASC SURG 80 1980 350 359
6. W Ganz K Tamura HS Marcus R Donoso S Yoshida JC Swan Measurement of coronary sinus blood flow by continuous thermodilution in man Circulation 19 1971 181 195
7. L Jorfeldt A Juhlin-Dannfelt The influence of ethanol on splanchnic and skeletal muscle metabolism in man Metabolism 27 1978 97 106
8. E Bernt HU Bergmayer l-Glutamat: UV-test mit Glutamat-Dehydrogenase und NAD 3rd ed HU Bergmayer Metoden der enzymatischen analyse 1974 Verlag Chemie Weinheim, Germany 1749 1753
9. FH Schmidt Die enzymatische bestimmung von glukose und fructose Klin Wochenschr 39 1961 1244 1247
10. W Barthelmai R Czok Enzymatische bestimmungen der glukose in blut, liquor und hirn Klin Wochenschr 40 1962 585 589
11. L Jorfeldt A Juhlin-Dannfeldt The influence of ethanol on human splanchnic and skeletal muscle metabolism during exercise Scand J Clin Lab Invest 37 1977 609 618
12. 63Ni as tracer Anal Biochem 36 1970 105 113
13. KR Kanter DD Glower HV Schaff TJ Gardner Mechanism of defective oxygen extraction following global ischemia J Surg Res 30 1981 482 488
14. SK Lucas KR Kanter HV Schaff EB Elmer DD Glower TJ Gardner Reduced oxygen extraction during reperfusion: a consequence of global ischemic arrest J Surg Res 28 1980 434 441
15. ER Rosenkranz F Okamoto GD Buckberg JM Robertson J Vinten-Johansen HI. Bugyi Safety of prolonged aortic clamping with blood cardioplegia. III Aspartate enrichment of glutamate-blood cardioplegia in energy-depleted hearts after ischemic and reperfusion injury J THORAC CARDIOVASC SURG 91 1986 428 435
16. LM Dinkelborg RK Kinne MK Grieshaber Characterization and pH dependence of l-glutamate transport in sarcolemmal vesicles from rat hearts Am J Physiol 268 1995 H194 H201
17. FN Nilsson EE Berglin R Ekroth Effects of graded insulin infusions on plasma levels of free fatty acids, adrenaline and noradrenaline directly after open heart surgery Thorac Cardiovasc Surg 35 1987 96 100
18. A Thomassen TT Nielsen JP Bagger P Henningsen Effects of intravenous glutamate on substrate availability and utilization across the human heart and leg Metabolism 40 1991 378 384
19. SE Svensson R Svedjeholm R Ekroth Trauma metabolism and the heart; uptake of substrates and effects of insulin early after cardiac surgery J THORAC CARDIOVASC SURG 99 1990 1063 1073
20. AJ Drake JR Haines MM Noble Preferential uptake of lactate by the normal myocardium in dog Cardiovasc Res 14 1980 65 72
21. L. Opie Carbohydrates and Lipids 1st ed L Opie The heart. 1984 Grune & Stratton London 111 135
22. EW Gertz JA Wisneski R Neese JD Briston GL Searle JT Hanlon Myocardial lactate metabolism: evidence of lactate release during net extraction in man Circulation 63 1981 1273 1279
23. JM Wistbacka MV Lepojärvi KE Karlqvist Amino acid–enriched glucose-insulin-potassium infusion improves hemodynamic function after coronary surgery Infusionsther Transfusionsmed 22 1995 82 90
24. 1-Blockade early after coronary surgery: a hemodynamic, metabolic and electrophysiologic study with special reference to effects of metoprolol [thesis] 1990 Uppsala Univ Uppsala (Sweden)
25. ES Weinstein ML Spector EM Adams MD Yokum RW Humphrey DE Fry Mitochondrial and myocardial performance: response to ischemia and reperfusion Arch Surg 121 1986 324 329
26. OI Pisarenko MG Lepilin VE. Ivanov Cardiac metabolism and performance during L-glutamic acid infusion in postoperative cardiac failure Clin Sci 70 1986 7 12
27. S Slogoff AS Keats Does perioperative myocardial ischemia lead to postoperative myocardial infarction? Anesthesiology 62 1985 107 114
28. RC Smith JM Leung DT Mangano Postoperative myocardial ischemia in patients undergoing coronary artery bypass graft surgery Anesthesiology 74 1991 464 473
29. A Thomassen TT Nielsen JP Bagger AK Pedersen P Henningsen Antiischemic and metabolic effects of glutamate during pacing in patients with stable angina pectoris secondary to either coronary artery disease or syndrome X Am J Cardiol 68 1991 291 295