Evidence for abnormal pain processing in fibromyalgia syndrome

Pain Medicine

Volumn 2, Issue 3, 2001, Pages 208-215

  Staud, Roland ^a   Domingo, MaryAnn ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

FMS; Pain; Sensitization; Therapy

Indexed keywords

ANALGESIC AGENT;

ABDOMINAL PAIN; ALLODYNIA; BRAIN REGION; CHRONIC PAIN; CLINICAL FEATURE; CONTROLLED STUDY; FATIGUE; FEMALE; FIBROMYALGIA; HUMAN; HYPERALGESIA; INFECTION; INJURY; INSOMNIA; MALE; MEDICAL LITERATURE; NEUROENDOCRINE DISEASE; NEUROPATHY; PATHOPHYSIOLOGY; POSTHERPETIC NEURALGIA; REVIEW; TEMPORAL SUMMATION;

EID: 0035215018     PISSN: 15262375     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1526-4637.2001.01030.x     Document Type: Review

References (79)

1. The prevalence and characteristics of fibromyalgia in the general population
2. A prospective, longitudinal, multicenter study of service utilization and costs in fibromyalgia
3. The fibromyalgia syndrome: A consensus report on fibromyalgia and disability
4. A 5.5 year prospective study of self-reported musculoskeletal pain and of fibromyalgia in a female population: Significance and natural history
5. A four-year follow-up study in fibromyalgia. Relationship to chronic fatigue syndrome
6. Fibromyalgia outcome: The predictive values of symptom duration, physical activity, disability pension, and critical life events-a 4.5 year prospective study
7. If you have to prove you are ill, you can't get well. The object lesson of fibromyalgia
8. Fibromyalgia, chronic fatigue, and other iatrogenic diagnostic algorithms. Do some labels escalate illness in vulnerable patients?
9. Fibromyalgia: La Maladie est Morte. Vive le Malade!
10. Consultation-liaison psychiatrists' management of somatoform disorders
11. Measuring the epidemiology of distress: The rheumatology distress index
12. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee
13. Diagnosis, etiology, and therapy of fibromyalgia
14. Aspects of fibromyalgia in the general population: Sex, pain threshold, and fibromyalgia symptoms
15. The relation between tender points and fibromyalgia symptom variables: Evidence that fibromyalgia is not a discrete disorder in the clinic
16. Two contributions to understanding of the "fibrositis" syndrome
17. Posttraumatic stress disorder, tenderness and fibromyalgia
18. Established fibromyalgia syndrome and parvovirus B19 infection
19. Fibromyalgia in human immunodeficiency virus infection
20. Do infections trigger fibromyalgia?
21. Fibromyalgia-associated hepatitis C virus infection
22. Evaluation of the relationship between depression and fibromyalgia syndrome: Why aren't all patients depressed?
23. Prevalence and impact of posttraumatic stress disorder-like symptoms on patients with fibromyalgia syndrome
24. Chronic pain and health care utilization in women with a history of childhood sexual abuse
25. Fibromyalgia syndrome in patients infected with human immunodeficiency virus. The Boston City Hospital Clinical AIDS Team
26. Fibromyalgia in hepatitis C virus infection. Another infectious disease relationship
27. Lyme disease associated with fibromyalgia
28. Increased rates of fibromyalgia following cervical spine injury. A controlled study of 161 cases of traumatic injury
29. The craniocervical connection: A retrospective analysis of 300 whiplash patients with cervical and temporomandibular disorders
30. Post-traumatic fibromyalgia. A long-term follow-up
31. Muscle pathology in primary fibromyalgia syndrome: A light microscopic, histochemical and ultrastructural study
32. Muscle biopsy findings in primary fibromyalgia and other forms of nonarticular rheumatism
33. Fiber type composition of the human female trapezius muscle: Enzyme-histochemical characteristics
34. Lack of association between fibromyalgia syndrome and abnormalities in muscle energy metabolism
35. Fibromyalgia is not a muscle disorder
36. The neuroscience and endocrinology of fibromyalgia
37. Chronic pain and fatigue syndromes: Overlapping clinical and neuroendocrine features and potential pathogenic mechanisms
38. Evidence for and pathophysiologic implications of hypothalamic-pituitary-adrenal axis dysregulation in fibromyalgia and chronic fatigue syndrome
39. Altered reactivity of the hypothalamic-pituitary-adrenal axis in the primary fibromyalgia syndrome
40. Chronic fatigue syndrome and fibromyalgia. Dilemmas in diagnosis and clinical management
41. Modeling the involvement of the hypothalamic-pituitary-adrenal and hypothalamic-pituitary-gonadal axes in autoimmune and stress-related rheumatic syndromes in women
42. The immune-inflammatory pathophysiology of fibromyalgia: Increased serum soluble gp130, the common signal transducer protein of various neurotrophic cytokines
43. Differential hypothalamic-pituitary-adrenal axis reactivity to psychological and physical stress
44. Growth hormone and cortisol secretion in relation to sleep and wakefulness
45. Musculoskeletal symptoms and non-REM sleep disturbance in patients with "fibrositis syndrome" and healthy subjects
46. Disordered growth hormone secretion in fibromyalgia: A review of recent findings and a hypothesized etiology
47. Hypothalamic-pituitary-insulin-like growth factor-I axis dysfunction in patients with fibromyalgia
48. A randomized, double-blind, placebo-controlled study of growth hormone in the treatment of fibromyalgia
49. Biochemische Veranderungen bei der Fibromyalgie
50. Secretory pattern of GH, TSH, thyroid hormones, ACTH, cortisol, FSH, and LH in patients with fibromyalgia syndrome following systemic injection of the relevant hypothalamic-releasing hormones
51. Pituitary release of growth hormone and prolactin in the primary fibromyalgia syndrome
52. Serum interleukin-1, interleukin-2, interleukin-6, and prolactin levels are not associated with the severity of disease in patients with the irritable bowel syndrome, with or without concomitant fibromyalgia
53. Sleep in fibromyalgia patients: Subjective and objective findings
54. Actinographically recorded motor activity and immobility across sleep cycles and stages in healthy male subjects
55. Periodic K-alpha sleep EEG activity and periodic limb movements during sleep: Comparisons of clinical features and sleep parameters
56. Periodic K-alpha sleep EEG activity and periodic limb movements during sleep: Comparisons of clinical features and sleep parameters
57. Elevated cerebrospinal fluid levels of substance P in patients with the fibromyalgia syndrome
58. Supraspinal contributions to
59. Cerebrospinal fluid (CSF) substance P (SP) in fibromyalgia (FMS): Changes in CSP SP over time parallel changes in clinical activity
60. Cerebrospinal fluid (CSF) levels of substance P (SP) are abnormal in patients with fibromyalgia (FM) regardless of traumatic or insidious pain onset
61. Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation
62. Potent antihyperalgesic activity without tolerance produced by glycine site antagonist of N-methyl-D-aspartate receptor GV196771A
63. NMDA-receptor antagonist in pain therapy
64. Abnormal sensitization and temporal summation of second pain (wind-up) in patients with fibromyalgia syndrome
65. The effect of exercise on temporal summation of second pain (wind-up) in patients with fibromyalgia syndrome
66. The functional neuroanatomy of major depression: An fMRI study using an emotional activation paradigm
67. Functional imaging-PET and FMRI: Functional activation studies on central motor control. Part I. Physiological aspects
68. Cerebral response to pain in two depressed patients
69. Positron emission tomography as a research tool in the investigation of psychiatric and psychological disorders
70. Altered brain activation in schizophrenia during visually guided motor selection revealed by fMRI
71. Acute pain produces abnormal regional cerebral blood flow (rCBF) in the anterior cingulate (AC) cortex in patients with fibromyalgia (FM)
72. Fibromyalgia in women. Abnormalities of regional cerebral blood flow in the thalamus and the caudate nucleus are associated with low pain threshold levels
73. Abnormal regional cerebral blood flow in the caudate nucleus among fibromyalgia patients and non-patients is associated with insidious symptom onset
74. Familial painful restless legs syndrome correlates with pain dependent variation of blood flow to the caudate, thalamus, and anterior cingulate gyrus
75. Unilateral decrease in thalamic activity observed with positron emission tomography in patients with chronic neuropathic pain
76. Is Chiari malformation associated with increased levels of substance P and clinical symptoms in persons with fibromyalgia?
77. Prevalence of Chiari malformation, and cervical stenosis, in fibromyalgia
78. Comparison of amitriptyline, cyclobenzaprine, and placebo in the treatment of fibromyalgia. A randomized, double-blind clinical trial
79. A review of the role of tricyclic medications in the treatment of fibromyalgia syndrome